A5088357109- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Mobile Health and mHealth Applications
- HIV/AIDS Impact and Responses
- Chronic Disease Management Strategies
- Reproductive tract infections research
- HIV, Drug Use, Sexual Risk
- Reproductive System and Pregnancy
- HIV Research and Treatment
- Primary Care and Health Outcomes
- Sex work and related issues
- Nutrition and Health in Aging
- Mental Health and Patient Involvement
- Medication Adherence and Compliance
- Adolescent Sexual and Reproductive Health
- Healthcare Systems and Practices
- Frailty in Older Adults
- COVID-19 and healthcare impacts
- Parasitic Diseases Research and Treatment
- Genital Health and Disease
- Syphilis Diagnosis and Treatment
- Reproductive Health and Contraception
- Migration, Health and Trauma
- Gender Roles and Identity Studies
University Hospitals Sussex NHS Foundation Trust
2013-2023
Sussex Community NHS Foundation Trust
2022
Research Institute for Tropical Medicine
2021
University of Brighton
2020
Royal Sussex County Hospital
2015
Brighton and Sussex Medical School
2012
Hospital for Tropical Diseases
2004
Hospital for Tropical Diseases
2003
Mortimer Market Centre
2003
Objectives People living with HIV (PLWH) have multidimensional concerns requiring person‐centred care. Routine use of patient‐reported outcome measures ( PROM s) improves outcomes. No brief currently reflects the breadth for PLWH. This study sought to identify priority outcomes PLWH, model current practice, explore views on introducing s into routine care, and devise a care incorporating . Methods A cross‐national multi‐centre (London, Brighton Dublin) was carried out. Semi‐structured...
Background: Mucosal leishmaniasis (ML) is an important complication of new world cutaneous (CL) caused by species the Leishmania Viannia subgenus. Previous reports ML among travellers to Latin America are few.
The control of HIV/AIDS has been a contemporary public health success story however, whilst infection rates are falling and people living longer due to antiretroviral therapy, adolescents young remain disproportionally affected. Infection AIDS-related deaths continue increase in these age groups some areas globally. This primarily attributed structural barriers including HIV-services not being youth friendly with opening hours conflicting school time, fears around unintended disclosure...
Couples wishing to have biological children when one partner is HIV positive and the other negative present clinicians with complex clinical, social ethical considerations. We established two multidisciplinary pre-conception services for HIV-positive individuals their partners. report first UK use of pre-exposure prophylaxis conception (PrEP-C) as part an overall risk reduction strategy. were counselled written informed consent PrEP-C was obtained. Patient demographics, medical histories...
People living with HIV experience burdensome multidimensional symptoms and concerns requiring person-centred care. Routine use of patient reported outcome measures can improve outcomes. There is no brief measure (PROM) that currently reflects the breadth for people HIV. This study aimed to develop cognitively test a novel within routine adult care- "Positive Outcomes" PROM.
We examined the impact of Covid-19 restrictions on wellbeing and access to care among people living with HIV (PLWH) in UK. A cross-sectional anonymous online survey was circulated PLWH attending at three services Sussex. The questionnaire covered key themes: socio-demographic characteristics; changes physical mental health; accessibility essential health information; socio-economic concerns. Free-text qualitative responses were through framework analysis. Quantitative data from 653...
In this article, we described a new mobile-Health (mHealth) supported clinical pathway of care for people living with medically stable HIV in terms platform acceptability, usability and technical feasibility. The EmERGE mHealth was codesigned clinicians the community, developed using Scrum agile methodology, integrated hospital information systems validated large prospective cohort study 2251 participants. evaluation paradigm conducted tailored Health Technology Assessment: Model Assessment...
Abstract Objectives Despite successful treatment, people living with HIV experience persisting and burdensome multidimensional problems. We aimed to assess the validity, reliability responsiveness of Positive Outcomes, a patient‐reported outcome measure for use in clinical practice. Methods In all, 1392 outpatients five European countries self‐completed PAM‐13 (patient empowerment), PROQOL‐HIV (quality life) FRAIL (frailty) at baseline 12 months. Analysis assessed: (a) validity (structural,...
Objective A multicentre, randomised non-inferiority trial compared the efficacy and safety of 14 days ofloxacin metronidazole (standard-of-care (SoC)) versus a single dose intramuscular ceftriaxone followed by 5 azithromycin (intervention arm (IA)) in women with mild-to-moderate pelvic inflammatory disease (PID). Methods Women clinical diagnosis PID presenting at sexual health services were to SoC or IA arms. Treating clinicians participants not blinded treatment allocation but clinician...
<h3>Background/introduction</h3> Mycoplasma genitalium (MG) is increasingly implicated in PID pathogenesis with many studies showing MG as common chlamydia high-risk women. Current treatment guidelines specify antibiotics low efficacy against MG. Increasing reports of macrolide resistance suggests first line for (azithromycin) may have limitations. <h3>Aim(s)/objectives</h3> To document rates a cohort women acute PID, and the proportion baseline resistance. <h3>Methods</h3> As part...
We aimed to evaluate the usability and acceptability of a co-designed mobile health (mHealth) application (PrEP-EmERGE) within digital pathway support HIV pre-exposure prophylaxis (PrEP).This was cross-sectional study PrEP-EmERGE app. Data were collected via an online survey sent all PrEP EmERGE users in September 2021. Usability assessed with validated tool, System Scale (SUS). Acceptability using modified patient-reported experience measures (PREMs). Quantitative data analysed descriptive...
Abstract Objective To evaluate frailty, falls and perceptions of ageing among clinically stable individuals with HIV, engaged remote healthcare delivered via a novel smartphone application. Methods This was multi‐centre European c ross‐sectional, questionnaire‐based sub‐study EmERGE participants. Frailty assessed using the five‐item FRAIL scale. Present criteria were summed categorized as follows: 0, robust; 1–2, pre‐frail; 3–5, frail. Falls history EQ‐5D‐5L quality life measure completed....
AimTo estimate the cost-effectiveness of EmERGE Pathway Care for medically stable people living with HIV (PLHIV) at University Hospital Infectious Diseases (UHID), Zagreb. The includes a mobile application enabling individuals to communicate their caregivers.MethodsThis study involving 293 participants collected data on use outpatient services one year before and after implementation. In departments supporting outpatients, micro-costing exercise was performed calculate unit costs. These were...
<h3>Background/introduction</h3> Crucial to treatment success in PID is adherence therapy. All guidelines recommend 14-days of therapy although many women fail complete 2-weeks, particularly if they experience side-effects. A shorter course antibiotics may offer a valuable alternative. <h3>Aim(s)/objectives</h3> To compare clinical efficacy/acceptability standard with 5-day for mild-moderate (pain <30 days). <h3>Methods</h3> multicentre, open-label, non-inferiority RCT comparing arm-1...
This study estimated the efficiency of implementing EmERGE Pathway Care for people living with medically stable HIV in Brighton, UK; an App enables individuals to communicate caregivers via their smart-phone. Individual data on use outpatient services were collected one-year pre- and post-implementation EmERGE. Unit costs calculated linked mean per patient year. Primary outcomes CD4 count viral load; activation quality-of-life measures secondary outcomes. 565 participants followed up April...
<h3>Background</h3> 'PrEP-EmERGE' is a co-designed digital health innovation that supports HIV-PrEP users via novel digital-health pathway and mobile-health application. <h3>Method</h3> A cross sectional study using mixed-methods approach evaluating the usability acceptability of PrEP-EmERGE app. Data were collected an online survey sent to all active in September-2021. Usability was assessed validated tool, (SUS). Acceptability modified (PREMs). Thematic analysis used analyse free-text...