A5116094498- Tissue Engineering and Regenerative Medicine
- Power Systems and Technologies
- Manufacturing Process and Optimization
- Extracellular vesicles in disease
- Additive Manufacturing and 3D Printing Technologies
- Aluminum Alloys Composites Properties
- Injection Molding Process and Properties
- Intermetallics and Advanced Alloy Properties
- Power Line Inspection Robots
- Spinal Cord Injury Research
- Cardiovascular Disease and Adiposity
- Metallurgy and Material Forming
- Additive Manufacturing Materials and Processes
- Aerodynamics and Acoustics in Jet Flows
- Metal Alloys Wear and Properties
- Covalent Organic Framework Applications
- Hydraulic and Pneumatic Systems
- IPv6, Mobility, Handover, Networks, Security
- Neurogenesis and neuroplasticity mechanisms
- Advanced Sensor and Control Systems
- Pulsed Power Technology Applications
- Mobile Agent-Based Network Management
- Advanced Vision and Imaging
- Cervical and Thoracic Myelopathy
- Metallic Glasses and Amorphous Alloys
Hunan University
2025
Jilin University
2023-2024
Xiangtan University
2024
Union Hospital
2024
Changzhou Vocational Institute of Engineering
2021-2023
First Affiliated Hospital of Nanchang University
2014-2023
Nanchang University
2014-2023
Changzhou No.2 People's Hospital
2021
Tongji University
2019
General Hospital of Guangzhou Military Command
2015
Abstract Background A growing body of research shows that drug monomers from traditional Chinese herbal medicines have antineuroinflammatory and neuroprotective effects can significantly improve the recovery motor function after spinal cord injury (SCI). Here, we explore role molecular mechanisms Alpinetin on activating microglia‐mediated neuroinflammation neuronal apoptosis SCI. Methods Stimulation microglia with lipopolysaccharide (LPS) to simulate models in vitro, effect release...
Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs), due to their inner functional substances, have shown great value in treating acute myocardial infarction (AMI). However, clinical application is limited by a low yield. In the present study, we cultured EVs using hollow fiber bioreactor-based three-dimensional (3D) system, and assessed therapeutic effectiveness on AMI.The MSCs separated fresh human umbilical cord were planted into flasks of two systems: two-dimensional...
Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated cardioprotection. This study aimed to investigate the cardioprotective function and underlying mechanisms of EVs derived from HIF-1α engineered mesenchymal stem cells (MSCs) a rat model AMI.EVs isolated MSCs (HIF-1α-EVs) control (NC-EVs) were prepared. In vitro experiments, incubated with cardiomyocytes endothelial exposed hypoxia serum deprivation (H/SD); vivo injected acutely infarcted hearts...
Fibrotic scar is one of the main impediments to axon regeneration following spinal cord injury (SCI). In this study, we found that CD44 was upregulated during formation fibrotic scar, and blocking by IM7 caused downregulation fibrosis-related extracellular matrix proteins at both 2 12 weeks post-spinal injury. More Biotinylated dextran amine (BDA)-traced corticospinal tract axons crossed area extended into distal region after administration. A recovery motor sensory function observed based...
Accumulating evidence has revealed that an elevated expression level of Aurora‑B is associated with metastasis in various types malignant tumor. However, it currently unclear whether this molecule involved non‑small lung cancer (NSCLC) metastasis, and the molecular mechanisms remain unknown. In present study, order to investigate development NSCLC, protein NSCLC tissues was detected by immunohistochemistry its association analyzed. The results levels obtained from patients lymph node were...
The dimensional accuracy of shells and binders investment casting which incorporation with selective laser sintering is investigated. results show that the colloidal silica higher than ethyl silicate, variation rate produced much lower silicate shells. Moreover, possesses better performance on environmental protection production cost control. These indicate comprehensive properties are silicate. Meanwhile, average single shell silicate-colloidal alteration was almost identical it other were...
Abstract High‐speed cameras are able to effectively and efficiently obtain the location of moving objects over time in many practical applications. In order meet requirement for fast computing processing object‐tracking process, this paper adopts parallel process multiple video‐image sequences by using open multi‐processing (Open MP ) single‐instruction data ( SIMD simultaneously, combined with a coarse‐to‐fine matching method. Experimental results showed that proposed method: (1) has high...
Rapid Investment Casting can overcome the cost involved in designing and fabrication of metal tooling for wax injection process. The present investigation is aimed to determine effects CAD model placement degree size on dimension error prototype base Selective Laser Sintering. experimental results show that change law length, width height different from each other, it mainly due intersection angle between important edge forming plane. When 0° 90°, staircase effect smaller accuracy higher,...
There are four kinds of ultra-precision lapping machine bed were developed: with/without reinforcing rib, a pair closed sides. The finite element analysis was used to find the optimal design bed. 3D model built by SolidWorks, and ANSYS software for static modal analysis. results suggest that when rib sides owned, had some better dynamic characteristics. mix-deformation this 1.911μm, first-order inherent frequency 101.74Hz.
Fibrotic scar is one of the main impediments to axon regeneration following spinal cord injury. In this study, we found that CD44 was up-regulated during formation fibrotic scar, and blocking resulted in down-regulation fibrosis-related extracellular matrix proteins at both 2 12 weeks post-spinal More BDA-traced corticospinal tract axons crossed area extended into distal region after IM7 administration. A recovery motor sensory function observed based on BMS scores tail-flick test. vitro...
The SLS (Selective Laser Sintering, SLS) technology can directly manufacturing any complex structure, however, due to the limitation of engineering factor, surface quality and dimension accuracy green part are still an outstanding problem. So, experimental methods were adopted study effect orientation on machining accuracy, will significantly affects outline stair-stepping phenomenon, then accuracy. samples different orientations including 0, 20, 45, 60, 90 degree fabricated, results...
In this paper, we discuss a new coastal tide collecting technology which is based on the integration of CDMA Wireless network and GPS-RTK technology. With technology, can get real-time level easily. At same time, FFT that used for signal extraction also discussed. Finally, its accuracy verified by experiment.
The knitting method have received much attention and applied in synthesized microporous organic polymers recent years due to its simple synthetic procedure wide adaptability. MOBP F contained MOFBP were prepared by this way our study. two show large BET surface area (917 m 2 g -1 ), pore volume (0.77 cm 3 ) favorable PCMs capacities. Shape stable phase change composites obtained using auto adsorption method. From differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA)...