Alexandro Chu

ORCID: 0000-0003-0201-2630
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About
Contact & Profiles
Research Areas
  • Dermatology and Skin Diseases
  • Food Allergy and Anaphylaxis Research
  • Urticaria and Related Conditions
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Transgenic Plants and Applications
  • Cutaneous lymphoproliferative disorders research
  • Mast cells and histamine
  • Microbial Metabolites in Food Biotechnology
  • SARS-CoV-2 and COVID-19 Research
  • Contact Dermatitis and Allergies
  • Meta-analysis and systematic reviews
  • Lymphoma Diagnosis and Treatment
  • Vaccine Coverage and Hesitancy
  • Eosinophilic Esophagitis
  • Biomedical Research and Pathophysiology
  • Infant Health and Development
  • Advanced Fluorescence Microscopy Techniques
  • Nutrition, Genetics, and Disease
  • Nonmelanoma Skin Cancer Studies
  • Digestive system and related health
  • Photodynamic Therapy Research Studies
  • Histiocytic Disorders and Treatments
  • Delphi Technique in Research
  • T-cell and B-cell Immunology

McMaster University
2022-2025

Impact
2023

St. Joseph’s Healthcare Hamilton
2023

Hamilton Health Sciences
2022

Imperial College Healthcare NHS Trust
2011-2016

Columbia University
1982

Guy's Hospital
1981-1982

Cow's milk allergy (CMA) is the most common food in infants. The replacement with specialized formulas an established clinical approach to ensure adequate growth and minimize risk of severe allergic reactions when breastfeeding not possible. Still, given availability multiple options, such as extensively hydrolyzed cow's protein formula (eHF-CM), amino acid (AAF), rice (HRF) soy (SF), there some uncertainty suitable choice respect health outcomes. Furthermore, addition probiotics a has been...

10.1016/j.waojou.2024.100888 article EN cc-by-nc-nd World Allergy Organization Journal 2024-03-26

Two murine monoclonal antibodies (BE1 and BE2), produced by using leukemic helper T cells from a patient with cutaneous T-cell lymphoma (CTCL) as immunogens, reacted selectively CTCL lymphocytes some transformed cultured lymphocytes, determined radioimmunoassay (RIA) indirect immunofluorescence (IIF). BE1 significantly (P less than or equal to 0.001) infiltrated lymph nodes (RIA, mean +/- SD = 776 275 cpm), compared background counts (263 68). binding normal blood mononuclear 283 58 cpm) was...

10.1172/jci110719 article EN Journal of Clinical Investigation 1982-12-01

Abstract Several tools are available for assessing the methodological quality of systematic reviews. The ReMarQ tool – centred on assessment reporting reviews comprises 26 dichotomous items and does not require clinical or background knowledge review topic its application. In this study, we aimed to compare results evaluating using A MeaSurement Tool Assess Reviews (AMSTAR) 2. We assessed a sample randomly selected published in medical journals AMSTAR calculated correlation agreement between...

10.1002/gin2.70021 article EN cc-by Deleted Journal 2025-03-29

The two cases reported in this paper allow the differentiation pagetoid reticulosis from solitary lesions of mycosis on basis clinical, histological ultrustructural immunohistochemical and enzyme histochemical studies. first patient presented with a slowly growing asymptomatic scaly plaque 30 years duration Histology lesion was typical reticulosis. Immunohistochemical studies showed that abnormal cells present cutaneous infiltrate were not T lymphocytes ultrastructural suggested these...

10.1111/j.1600-0560.1981.tb00984.x article EN Journal of Cutaneous Pathology 1981-02-01

Journal Article Follicular mucinosis associated with mycosis fungoides presenting gross cystic changes on the face Get access J.D. WILKINSON, WILKINSON Department of Dermatology, St Thomas’Hospital, London SE1 7EH Search for other works by this author on: Oxford Academic Google Scholar M.M. BLACK, BLACK A. CHU Guy's Hospital, Thomas' Street, 9RT Clinical and Experimental Volume 7, Issue 3, 1 May 1982, Pages 333–340, https://doi.org/10.1111/j.1365-2230.1982.tb02436.x Published: 01 1982...

10.1111/j.1365-2230.1982.tb02436.x article EN Clinical and Experimental Dermatology 1982-05-01

Cow's milk allergy (CMA) is the most complex and common food in infants. Elimination of cow's from diet replacement with a specialized formula for infants who cannot be breastfed an established approach to minimize risk severe allergic reactions while avoiding nutritional deficiencies. Given availability multiple options, such as extensively hydrolyzed milk-based (eHF-CM), aminoacid (AAF), rice (HRF), soy (SF), there some uncertainty regarding which might represent suitable choice respect...

10.1016/j.waojou.2024.100947 article EN cc-by-nc-nd World Allergy Organization Journal 2024-09-01

Background Transparent and detailed reporting of randomized controlled trials (RCTs) is essential to judge its validity generalizability. We assessed the quality RCTs examining effects inulin-type fructans supplementation on cardiovascular risk factors, before after publication Consolidated Standards Reporting Trials (CONSORT) in 2010. Methods searched MEDLINE, EMBASE, Emcare, AMED, Cochrane Library, CINAHL from inception May 15, 2022, including reference lists selected RCTs. screened titles...

10.1371/journal.pone.0292184 article EN cc-by PLoS ONE 2024-01-02

To aid the in vivo diagnosis of skin lesions, we present design and implementation a 4 channel FLIM detector hyperspectral imaging into clinically licensed commercial two-photon tomograph. We have also implemented image segmentation algorithms to facilitate automated processing large volumes data produced. The first is based on multispectral time correlated single photon counting, providing four fluorescence lifetime images. second prism-based CCD imager. These detectors provide capability...

10.1117/12.873567 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2011-02-10
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