Lynda C. Schneider

ORCID: 0000-0002-5633-0178
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About
Contact & Profiles
Research Areas
  • Food Allergy and Anaphylaxis Research
  • Dermatology and Skin Diseases
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Eosinophilic Esophagitis
  • Urticaria and Related Conditions
  • Contact Dermatitis and Allergies
  • Immunodeficiency and Autoimmune Disorders
  • Respiratory and Cough-Related Research
  • Drug-Induced Adverse Reactions
  • Immune Cell Function and Interaction
  • Transgenic Plants and Applications
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • T-cell and B-cell Immunology
  • NF-κB Signaling Pathways
  • Food Safety and Hygiene
  • Pediatric health and respiratory diseases
  • Blood disorders and treatments
  • IL-33, ST2, and ILC Pathways
  • Inhalation and Respiratory Drug Delivery
  • Hemophilia Treatment and Research
  • Mast cells and histamine
  • Autoimmune Bullous Skin Diseases
  • Pancreatic function and diabetes
  • Viral gastroenteritis research and epidemiology

Boston Children's Hospital
2016-2025

Harvard University
2016-2025

Robert Koch Institute
2025

European Centre for Disease Prevention and Control
2025

Walsh University
2024

Boston Children's Museum
2013-2024

Swiss Red Cross
2023

University College London
2021

The George Institute for Global Health
2021

RELX Group (United States)
2020

Peanut-induced anaphylaxis is an IgE-mediated condition that estimated to affect 1.5 million people and cause 50 100 deaths per year in the United States. TNX-901 a humanized IgG1 monoclonal antibody against IgE recognizes masks epitope CH3 region of responsible for binding high-affinity Fcε receptor on mast cells basophils.

10.1056/nejmoa022613 article EN New England Journal of Medicine 2003-03-13

Rating scales for assessing the mentally ill usually focus on role functioning of clients and their psychiatric symptomatology. This article introduces a rating scale to measure more directly observable behavioral daily living skills in mental hospitals community. Results are presented from series studies designed test instrument's psychometric properties.

10.1093/swra/19.3.9 article EN Social Work Research and Abstracts 1983-09-01

There are currently no approved treatments for peanut allergy.To assess the efficacy and adverse events of epicutaneous immunotherapy with a patch among peanut-allergic children.Phase 3, randomized, double-blind, placebo-controlled trial conducted at 31 sites in 5 countries between January 8, 2016, August 18, 2017. Participants included children (aged 4-11 years [n = 356] without history severe anaphylactic reaction) developing objective symptoms during food challenge an eliciting dose 300...

10.1001/jama.2019.1113 article EN JAMA 2019-02-23

<h3>Importance</h3> Epicutaneous immunotherapy may have potential for treating peanut allergy but has been assessed only in preclinical and early human trials. <h3>Objective</h3> To determine the optimal dose, adverse events (AEs), efficacy of a patch treatment. <h3>Design, Setting, Participants</h3> Phase 2b double-blind, placebo-controlled, dose-ranging trial peanut-allergic patients (6-55 years) from 22 centers, with 2-year, open-label extension (July 31, 2012-July 2014; completed...

10.1001/jama.2017.16591 article EN cc-by JAMA 2017-11-14

No approved treatment for peanut allergy exists children younger than 4 years of age, and the efficacy safety epicutaneous immunotherapy with a patch in toddlers are unknown. We conducted this phase 3, multicenter, double-blind, randomized, placebo-controlled trial involving 1 to 3 age confirmed by food challenge. Patients who had an eliciting dose (the necessary elicit allergic reaction) 300 mg or less protein were assigned 2:1 ratio receive delivered means (intervention group) placebo...

10.1056/nejmoa2212895 article EN New England Journal of Medicine 2023-05-10
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