A5082397263- Pesticide Exposure and Toxicity
- Health, Environment, Cognitive Aging
- Toxic Organic Pollutants Impact
- Environmental Toxicology and Ecotoxicology
- Carcinogens and Genotoxicity Assessment
- Pesticide and Herbicide Environmental Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Pregnancy and Medication Impact
- Iron Metabolism and Disorders
- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Folate and B Vitamins Research
- Chemical Analysis and Environmental Impact
- Per- and polyfluoroalkyl substances research
- Air Quality and Health Impacts
- Human Health and Disease
Chulalongkorn University
2021-2024
Chiang Mai University
2019-2021
Measurements of urinary dialkyl phosphate (DAP) metabolites are often used to characterize exposures organophosphate (OP) insecticides; however, some challenges using DAP as an exposure measure exist. OP insecticides have short biological half-lives with measurement in a single urine sample typically only reflecting recent within the last few days. Because field staff and participant burden longitudinal collection high cost multiple measurements, one or two samples been evaluate insecticide...
Prenatal exposure to pesticides has been linked adverse neurodevelopmental outcomes. Gaps exist in the current literature about timing and magnitude of exposures that result these outcomes.The Study Asian Women their Offspring's Development Environmental Exposures (SAWASDEE) cohort was established investigate impact prenatal on early indicators cognitive motor skills, inhibitory control, emotion regulation, memory have found be important development subsequent neurobehavioral diseases. The...
Introduction Organophosphate (OP) insecticides are among the most abundantly used worldwide. Thailand ranked third 15 Asian countries in its use of pesticides per unit hectare and fourth annual pesticide use. More than 40% Thai women childbearing age work on farms where applied. Thus, potential for pregnant their fetuses to be exposed is significant. This study investigated relationship between early, mid, late pregnancy maternal urine concentrations OP metabolites infant neural integrity at...
Abstract Prenatal pesticide exposure may adversely affect child neurodevelopment which partly arise from impairing the placenta’s vital role in fetal development. In a cohort of pregnant farmworkers Thailand (N=248), we examined links between urinary metabolites pyrethroid pesticides during pregnancy, placental gene expression networks derived transcriptome sequencing, and newborn neurobehavior assessed using NICU Network Neurobehavioral Scales (NNNS) at 5 weeks age. Focusing on 21 network...
We investigated the effect of exposure to pesticide mixtures during pregnancy on placental transcriptome, link these exposures and functions. The Study Asian Women their Offspring's Development Environmental Exposures (SAWASDEE) enrolled pregnant farmworkers from Thailand (n=248), who were primarily exposed organophosphate (OP) pyrethroid pesticides. measured maternal urinary levels six non-specific OP metabolites expressed as three summary measures (dimethylalkylphosphates (DMAP),...
TPS 741: Adverse birth outcomes 2, Exhibition Hall, Ground floor, August 28, 2019, 3:00 PM - 4:30 Background: The Study of Asian Women and Offspring's Development Environmental Exposures (SAWASDEE), a prospective cohort, has been initiated in two districts the Chiang Mai Province Northern Thailand. objectives this study are (1) to better understand exposures during critical developmental windows pregnancy; (2) examine direct effects prenatal insecticide exposure on neurodevelopment; (3)...
Background: Prenatal pesticide exposures have been associated with adverse neurodevelopmental outcomes in several studies. A prospective birth cohort, the Study of Asian Women and their Offspring's Development Environmental Exposures (SAWASDEE) evaluated association between self-reported exposure behaviors during early pregnancy neurodevelopment infants. We examined occupational settings to further understand potential sources prenatal implications for neurobehavioral Methods: Pregnant women...
Background and Aims Experimental studies have shown associations between organophosphate pesticides (OPs) fetal growth measurements, but these been inconsistent in epidemiological studies. We aimed to evaluate prenatal exposure OPs birth outcomes by including trimester specific measures of OPs. Methods recruited pregnant farmworker women Chom Thong Fang, two districts Chiang Mai province Thailand (N = 330) into the Study Asian Women their Offspring's Development Environmental Exposures...
<sec> <title>BACKGROUND</title> Prenatal exposure to pesticides has been linked adverse neurodevelopmental outcomes. Gaps exist in the current literature about timing and magnitude of exposures that result these </sec> <title>OBJECTIVE</title> The Study Asian Women their Offspring’s Development Environmental Exposures (SAWASDEE) cohort was established investigate impact prenatal on early indicators cognitive motor skills, inhibitory control, emotion regulation, memory have found be important...