Background Assessment of the gluten-induced small-intestinal mucosal injury remains cornerstone celiac disease diagnosis. Usually is evaluated using grouped classifications (e.g. Marsh groups), but this often too imprecise and ignores minor significant changes in mucosa. Consequently, there a need for validated continuous variables everyday practice academic pharmacological research. Methods We studied performance our standard operating procedure (SOP) on 93 selected biopsy specimens from...

Diagnosis of celiac disease may be problematic in that small-bowel villous atrophy sometimes occurs conjunction with other enteropathies, develops gradually and patchy. Furthermore, as the often compromised quality biopsy specimens renders diagnosis difficult, new diagnostic tools are warranted.As disease-specific autoantibodies found deposited at their production site, mucosa, they useful diagnostics, especially cases. We therefore systematically assessed occurrence celiac-specific...

This study describes and analyses how practices organise temporality to reduce food waste. The builds upon the material turn in practice theories an ontological approach that together highlight emerging relations between humans non-humans practices. Three theoretical propositions are constructed inform empirical analysis. utilises qualitative data from a Finnish blog campaign ‘From Waste Delicacy’. identifies four bundles of organising temporality: scheduling, pausing, stretching...

ABSTRACT Objectives: A gluten‐free diet omitting wheat, rye, and barley is the only effective treatment for coeliac disease. The necessity of excluding oats from has remained controversial. We studied toxicity in children with disease during a 2‐year follow‐up by investigating jejunal transglutaminase 2 (TG2)‐targeted IgA‐class autoantibody deposits, potentially more sensitive marker than serum antibodies or conventional histology. Patients Methods: Twenty‐three remission were randomized to...

ABSTRACT Objectives: In coeliac disease, immunoglobulin (Ig)A–class autoantibodies against transglutaminase‐2 are produced in the small intestinal mucosa, where they deposited extracellularly. It remains unclear whether positive transglutaminase‐2‐targeted IgA deposits subjects having normal bowel mucosal morphology signs of early‐stage disease. We evaluated gluten dependency these overt and mild enteropathy Patients Methods: All together 48 suspected disease but villi were enrolled; 28 them...

Dermatitis herpetiformis (DH) is an extraintestinal manifestation of coeliac disease. Untreated disease patients are known to have transglutaminase 2 (TG2)-targeted IgA deposits in the small bowel mucosa. To evaluate whether similar intestinal also present DH and disappear with gluten-free diet, 47 untreated 27 treated were studied. Seventy-nine percent 41% had TG2-specific bowel, presence showed a significant association degree villous atrophy (p < 0.001). Other coeliac-disease related...

Celiac disease is an autoimmune disorder wherein the ingestion of gluten causes villous atrophy small intestinal mucosa with crypt hyperplasia in genetically susceptible individuals. The classic symptoms are malabsorption, steatorrhea, weight loss, growth retardation, and failure to thrive (1,2). Dermatitis herpetiformis a well-known extraintestinal manifestation celiac disease, characterized by granular immunoglobulin A (IgA) deposits uninvolved skin (3). Approximately 17% patients have...

Background: Unstable family environment during childhood is known to predispose juvenile delinquency. Aims: This study explored whether structure associated with violent behaviour of adult offspring. Methods: We used a large, unselected general population birth cohort ( n = 5589 males) linked the national crime registers (up age 32 years). The Ministry Justice provided information on registered offences for all subjects. A logistic regression analysis was performed examine association...

The affective turn has highlighted the need to study emotions, visceral reactions and embodied experiences within social sciences, its importance also been recognized theories of practice. However, practice theoretical discussions affects, especially empirically grounded ones, are still sparse fragmented. This article seeks further these nascent by arguing that practices present one fruitful avenue forward. Originally introduced Margaret Wetherell psychology, theoretically developed in this...

In coeliac disease, ingestion of gluten induces the production transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in small intestinal mucosa untreated disease. During treatment with a gluten-free diet (GFD), number these decreases considerably. It has not been previously investigated whether are also prior to development villous atrophy, or non-responsive patients and those dietary lapses. We aimed define bowel mucosal disease varying...

Abstract While a circular economy (CE) paradigm shift has gained significant momentum among academics, practitioners, and policymakers, theory regarding its social aspects remains scant, especially based on an ethical, micro-level perspective. Circular consumption, referring to those consumption practices that aim extend the lifetimes of objects materials, involves ethical considerations. However, everyday ethics have not foothold in CE literature. This article builds existing literature by...

This article explores the ways through which care manifests in everyday food waste reduction practices. The is positioned within a more-than-human approach, emphasises blurred ontological and epistemological boundaries among across (assemblages of) humans, nonhumans, things issues (re)forming sociomaterial worlds. Drawing empirical insights from (n)ethnographic materials that have been generated an ongoing research project focusing on consumers as active reducers of waste, discusses three...

In the Global North, meat consumption is both an integral part of everyday diets and under increasing pressure to be reduced, owing its various harmful effects. There has been much research on issues that forestall less meat-dominated diets. Based interview participant observation data consumers with a wide variety relations in Finland, this article extends these discussions by framing issue as navigating contentious care. This enables two-fold contribution. First, brings together previously...

Parental lack or loss during childhood may increase the risk of later behavioural problems in offspring. Westudied association between violent recidivism and types single-parent family origin by using a prospectively collected general population birth cohort database (N = 5,589 males), 'the Northern Finland 1966 Birth Cohort'. The results showed that repeated offending was nearly eightfold if male child born to single mother who remained unmarried up child's 14th birthday. corresponding...