- Laser-Plasma Interactions and Diagnostics
- Laser-Matter Interactions and Applications
- Advanced Fiber Laser Technologies
- Solid State Laser Technologies
- Laser-induced spectroscopy and plasma
- Nanoplatforms for cancer theranostics
- ZnO doping and properties
- Advanced Semiconductor Detectors and Materials
- Chalcogenide Semiconductor Thin Films
- Laser Design and Applications
- Gas Sensing Nanomaterials and Sensors
- Semiconductor Quantum Structures and Devices
- Laser Material Processing Techniques
- High-pressure geophysics and materials
- Advanced X-ray Imaging Techniques
- Cancer Genomics and Diagnostics
- Advanced Optical Sensing Technologies
- Quantum Dots Synthesis And Properties
- Cancer-related molecular mechanisms research
- Photonic Crystal and Fiber Optics
- Photorefractive and Nonlinear Optics
- Polymer composites and self-healing
- Marine Biology and Environmental Chemistry
- Optical Polarization and Ellipsometry
- Copper-based nanomaterials and applications
Shanghai Institute of Optics and Fine Mechanics
2011-2025
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2017-2024
Central Hospital of Zibo
2023-2024
Nanjing University of Chinese Medicine
2024
Jiangsu Province Hospital
2024
Aerospace Information Research Institute
2022-2023
University of Maryland, Baltimore
2023
Beijing Institute of Optoelectronic Technology
2023
University of Mary
2023
One of the most significant challenges in diagnosis brain cancer is efficient vivo imaging using nontoxic nanoprobes. Core–shell gold nanorod@MIL-88(Fe) nanostars are successfully constructed as triple-modality (computed tomography/magnetic-resonance imaging/photoacoustic imaging) nanoprobes that show low cytotoxicity, high contrast, penetration depth, and spatial resolution for accurate noninvasive gliomas. As a service to our authors readers, this journal provides supporting information...
We report on near-GeV electron beam generation from an all-optical cascaded laser wakefield accelerator (LWFA). Electron injection and acceleration are successfully separated controlled in different LWFA stages by employing two gas cells filled with a $\mathrm{He}/{\mathrm{O}}_{2}$ mixture pure He gas, respectively. Electrons Maxwellian spectrum, generated the first assisted ionization-induced injection, were seeded into second 3-mm-thick cell accelerated to be 0.8-GeV quasimonoenergetic...
To improve patient outcome and decrease overall health-care costs, highly sensitive precise detection of a tumor is required for its accurate diagnosis efficient therapy; however, this remains challenge when using conventional single mode imaging. Here, we successfully designed near-infrared (NIR)-response photothermal therapy (PTT) platform (Au@MSNs-ICG) the location, diagnosis, NIR/computer tomography (CT) bimodal imaging-guided PTT tissues, gold (Au) nanospheres coated with indocyanine...
Abstract Settlement and metamorphosis of pediveliger larvae Mytilus coruscus in response to natural biofilms was investigated the laboratory. Pediveliger settled metamorphosed post-larval settlement increased with biofilm age. The activity positively correlated age, dry weight, bacterial density diatom density, but had no apparent relationship chlorophyll a concentration. change community composition corresponding age may explain differences age-dependent inducing activities biofilms, which...
We present a recent progress of the SG-II 5PW facility, which designed multi-petawatt ultrashort pulse laser based on optical parametric chirped-pulse amplification (OPCPA). The prior two amplifiers have been accomplished and chirped pulses with an energy 49.7 J full-width-at-half-maximum (FWHM) spectrum bandwidth 85 nm achieved. In PW-scale (OPA), pump that has 118 from second harmonic generation 7th beam, pump-to-signal conversion efficiency is up to 41.9%, best our knowledge highest among...
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The effect of drive laser wavelength on the growth ablative Rayleigh–Taylor instability (ARTI) in inertial confinement fusion (ICF) is studied with two-dimensional numerical simulations. results show that plasma acceleration phase, shorter wavelengths lead to more efficient coupling between and kinetic energy implosion fluid. Under condition coupled fluid constant, ARTI rate decreases as moves toward extreme ultraviolet band, reaching its minimum value near λ = 65 nm, when continuously X-ray...
Theranostic tantalum oxide nanoparticles (TaOxNPs) of about 40 nm were successfully developed by conjugating functional molecules including polyethylene glycol (PEG), near-infrared (NIR) fluorescent dye, doxorubicin (DOX), and hyaluronic acid (HA) onto the surface (TaOx@Cy7-DOX-PEG-HA NPs) for actively targeting delivery, pH-responsive drug release, NIR fluorescence/X-ray CT bimodal imaging. The obtained nanoagent exhibits good biocompatibility, high cumulative release rate in acidic...
// Qingshan Chen 1, 2, * , Wenting Shang 3, Chaoting Zeng 2 Kun Wang 3 Xiaoyuan Liang Chongwei Chi Xiao Jian Yang Chihua Fang 1 and Jie Tian Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China Key Laboratory Molecular Imaging, Institute Automation, Chinese Academy Sciences, Beijing 100190, These authors have contributed equally to this work Correspondence to: Fang, email: fangch_dr@126.com Tian, jie.tian@ia.ac.cn Keywords: liver...
For fine-grained human perception tasks such as pose estimation and activity recognition, radar-based sensors show advantages over optical cameras in low-visibility, privacy-aware, wall-occlusive environments. Radar transmits radio frequency signals to irradiate the target of interest store information echo signals. One common approach is transform echoes into radar images extract features with convolutional neural networks. This article introduces RadarFormer, first method that...
Abstract As optical parametric chirped pulse amplification has been widely adopted for the generation of extreme intensity laser sources, nonlinear crystals large aperture are demanded high-energy amplifiers. Yttrium calcium oxyborate (YCa 4 O(BO 3 ) , YCOB) is capable being grown with apertures exceeding 100 mm, which makes it possible application in systems petawatt scale. In this paper, we experimentally demonstrated first time to our knowledge, an ultra-broadband non-collinear amplifier...
We present the design and experiment of a broadband optical parametric chirped-pulse amplifier (OPCPA) which provides high conversion efficiency good beam quality at 808 nm wavelength. Using three-dimensional spatial temporal numerical model, several considerations necessary to achieve efficiency, output stability are discussed. To improve broaden amplified signal bandwidth simultaneously, nonlinear crystal length OPCPA parameters analyzed optimized with concept dissipating idler between...
Although they have been under development for years and are attracting a lot of attention, vision-based tactile sensors still common defects-the use such devices to infer the direction external forces is poorly investigated, operating frequency too low them be applied in practical scenarios. Moreover, discussion deformation elastomers used remains insufficient. This research focuses on analyzing thin elastic layer sensor by establishing simplified model, which cross-validated using finite...
We propose a simple single-shot spatiotemporal measurement technique called coherent modulation imaging for the spatio-spectrum (CMISS), which reconstructs full three-dimensional high-resolution characteristics of ultrashort pulses based on frequency-space division and imaging. demonstrated it experimentally by measuring amplitude phase single pulse with spatial resolution 44 µm accuracy 0.04 rad. CMISS has good potential high-power ultrashort-pulse laser facilities can measure even...
A novel chromatic aberration pre-compensation scheme for ultrashort petawatt laser systems was proposed. The consists of a convex lens, group concave lenses, and spherical reflector combined with conventional vacuum chamber. It provides versatile method to accurately compensate the an entire system via controlling amount propagation time delay (PTD) induced by compensator without changing input output beam size. compensator, tailored based on proposed scheme, designed experimentally...
Temporal contrast is one of the crucial physical determinants which guarantee successful performance laser–matter interaction experiments. We generally reviewed influences on temporal in three categories noises based requirement by mechanisms. The spatiotemporal at focal region chromatic aberration and propagation time difference introduced large-aperture broadband spatial filters, were spatiotemporally coupled with compression focusing, calculated discussed a practical case SG-II 5 PW...
We present a high efficiency and ultra-broadband optical parametric chirped-pulse amplification (OPCPA) system fully based on yttrium calcium oxyborate (YCOB) crystals. The OPCPA properties of YCOB at 808 nm are studied for both gain saturated amplification. non-collinear angle is finely tuned to study the variation spectrum certain phase-matching After by four crystals, total signal 0.9×109 obtained FWHM spectral bandwidth still over 100 nm. An amplified pulse 182 mJ achieved with pump...
This article proposes a three-dimensional (3D) human pose estimation method using through-wall radar (TWR) systems, which extends and supplements new applications in the era of Internet Things (IoT). TWR system can penetrate non-metallic obstacles perceive wall-occlusive targets, but physical characteristics radio frequency (RF) signals, such as poor imaging resolution specularity effect, make process highly ill-posed. In this work, we propose mutual information maximizing deeply-supervised...
We present an optical parametric chirped-pulse amplification (OPCPA) based on mixed cascaded crystals, taking advantage of the unique phase-matching lithium triborate (LiB