A5055852036- Sarcoma Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Bone Tumor Diagnosis and Treatments
- Total Knee Arthroplasty Outcomes
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Bone fractures and treatments
- Musculoskeletal synovial abnormalities and treatments
- Reconstructive Surgery and Microvascular Techniques
- Surgical site infection prevention
- Bone health and treatments
- Oral and Maxillofacial Pathology
- Hip and Femur Fractures
- Soft tissue tumor case studies
- Shoulder and Clavicle Injuries
- Infectious Diseases and Tuberculosis
- Tumors and Oncological Cases
- Vascular Tumors and Angiosarcomas
- Bone and Joint Diseases
- Hematological disorders and diagnostics
- COVID-19 and healthcare impacts
- Bone health and osteoporosis research
- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
University of Padua
2017-2025
Azienda Ospedaliera di Padova
2024
Clinical Orthopaedics and Related Research
2019
Committee on Publication Ethics
2019
Marymount University
2017
University of Bologna
2009-2016
Istituto Ortopedico Rizzoli
2010-2016
Ospedale Infermi di Rimini
2016
Athens State University
2015
University General Hospital Attikon
2015
Modular megaprostheses are now the most common method of reconstruction after segmental resection long bones in lower extremities. Previous studies reported variable outcome and failure rates knee megaprosthetic reconstructions.The objectives this study were to analyze results a modular tumor prosthesis bone around with respect (1) survivorship; (2) rate; (3) comparative survivorship against different sites reconstructions primary revision implants; (4) functional on Musculoskeletal Tumor...
Abstract Introduction Aim of this study was to analyze (1) survival, local recurrence (LR), and metastasis rates between the three histological tumor grades; (2) whether type treatment site influenced prognosis for each histologic grade. Methods We retrospectively studied 296 patients with central conventional chondrosarcomas (CS) (87 grade 1, 162 2, 47 3). The femur most common (91 cases), followed by pelvis (82) other less frequent sites. Type surgery related Margins were wide in 222...
Retrospectively analyze outcomes of current-generation Global Modular Replacement System (GMRS) modular tumor endoprosthesis for the lower limb in primary and secondary implantation procedures.Two hundred ninety five prostheses were implanted, 197 implants, 98 revision surgery; procedures included 84 failed reconstructions 14 non-tumor reconstructions. Anatomic sites included: distal femur 199; proximal tibia 60; 32;total 4. Endoprosthesis failures classified as soft-tissue (Type 1), aseptic...
Abstract Background Previous studies reported on surgical indications for patients with femoral metastases. However, few analyzed the spectrum of metastatic presentation. We performed this study to evaluate survival metastases, and clarify treatment impending actual pathological fractures. Materials Methods retrospectively studied 110 metastases from various cancers treated nailing or resection megaprosthetic reconstruction 1995 2010. The mean follow‐up was 18 months. Survival respect...
Background: Expandable prostheses offer the advantages of limb-salvage and limb-length equality at skeletal maturity. However, what is cost for achieving that goal, in how many children this achieved? Materials Methods: We present 32 (16 boys 16 girls; mean age, 9 y) with bone sarcomas femur treated limb salvage using expandable prostheses. The Kotz Growing prosthesis noninvasive Repiphysis Stanmore were used. follow-up was 49 months. Survival analysis primary implants functional evaluation...
The best treatment of sacral chordoma is surgical resection, nowadays associated with optimized radiation therapy. We analysed 1) the oncologic outcome in a large series; 2) effect previous intralesional surgery, resection level, tumor volume and margins on survivorship to local recurrence (LR) 3) complication rate.We reviewed 71 patients chordomas. Forty-eight resections were proximal S3. Mean was 535 cm3. Eleven received surgery elsewhere. Margins wide 44 resections, wide-contaminated 11,...
Abstract Background Previous studies reported on post‐radiation sarcomas. However, the incidence, latency from radiation therapy, treatment, and survival has been difficult to evaluate. We performed a retrospective, single‐institutional study determine these factors for Materials Methods retrospectively studied 52 patients with sarcomas diagnosed treated 1985 2011. The mean age was 49 years; 45 had bone 7 soft tissue sarcoma. follow‐up months. Survival analyzed respect at diagnosis, type...
The choices of treatment for patients with extensive tumors the femur include total megaprosthesis or large allograft-prosthetic composites. Previous reports suggest variable survival ranging from 60-70% at 1 to 2 years. However, these studies described earlier prostheses and techniques.To confirm previous we determined (1) risk local recurrence; (2) overall survivorship; (3) function in reconstructions tumors.We retrospectively reviewed 23 megaprostheses implanted between 1987 2006 after...
Abstract Background Previous studies reported variable outcome of proximal tibial resections and reconstructions. Therefore, we evaluated the survival, Musculoskeletal Tumor Society (MSTS) function, complications patients reconstructions in this location. Materials Methods We reviewed files 225 with tumors treated resection, fixed or rotating hinge megaprosthetic reconstruction extensor mechanism reattachment using sutures, mechanical clamping, artificial ligaments, and/or gastrocnemius flap...
The objective of this study was to assess outcome and recurrence rate after limb-salvage surgery with reconstruction for pelvic bone tumors analyze complications their relationship surgery. authors analyzed 129 patients followed a mean 6 years (range, 2–19 years). Chondrosarcoma the most frequent histotype. Thirty-one cases no acetabular involvement were reconstructed allograft only. Acetabular resections prosthetic composite (n=60), only (n=11), trabecular metal components (n=2), prosthesis...
Background: Infection of megaprostheses after bone tumor resection is a major concern; management challenging. This study evaluated the survivability from such infections, microbial isolates, treatment tactics, and outcome megaprosthesis reconstructions. Materials Methods: We studied 1,161 patients retrospectively who underwent reconstruction for limb salvage sarcoma 1983 to 2010. The mean followup was 9 y (range 3–20 y). overall survival reconstructions in with infection respect type...
Abstract Background According to the required reorganization of all hospital activities, recent COVID-19 pandemic had dramatic consequences on orthopedic world. We think that informing community about strategy we adopted both in our and Department Orthopedics could be useful, particularly for those who are facing later than Italy. Methods Changes were done by medical direction reallocate resources patients. In Orthopedic Department, a decrease number beds surgical activity was stabilized....
Abstract Background After proximal humerus resection for bone tumors, restoring anatomy and shoulder function remains demanding because muscles are removed to obtain tumor-free surgical margins. Current modes of reconstruction such as anatomic modular prostheses, osteoarticular allografts, or allograft-prosthetic composites arthrodeses associated with relatively poor related loss the deltoid rotator cuff muscles. Newer prosthetic designs like reverse total arthroplasty (RTSA) felt be useful...
Because chondrosarcomas vary widely in their behavior, and because anticipating behavior based on histology alone can be challenging, genetic markers represent an appealing area of inquiry that may help us refine our prognostic approaches. Isocitrate dehydrogenase (IDH) mutations are involved the pathogenesis a variety neoplasms, recently, IDH1/2 have been found tissue benign cartilage tumors as well conventional highly aggressive dedifferentiated chondrosarcomas. However, association with...
In Brief Study Design. Retrospective case series. Objective. To evaluate the risk of infection, related treatment, and outcome after surgery 2 most common primary sacral tumors. Summary Background Data. Rarity tumors has limited number population-based studies. Treatment depends on malignancy or local aggressiveness: wide resection is indicated for malignant lesions, intralesional benign. Methods. We studied 82 patients with chordomas (55 cases) giant cell tumor (GCT) (27 treated between...