Sanath Kumar

ORCID: 0000-0003-0223-9069
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Vibrio bacteria research studies
  • Aquaculture disease management and microbiota
  • Salmonella and Campylobacter epidemiology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Escherichia coli research studies
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Antibiotics Pharmacokinetics and Efficacy
  • Viral gastroenteritis research and epidemiology
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Meat and Animal Product Quality
  • Listeria monocytogenes in Food Safety
  • Bacteriophages and microbial interactions
  • Protein Hydrolysis and Bioactive Peptides
  • Aquaculture Nutrition and Growth
  • Identification and Quantification in Food
  • Parasite Biology and Host Interactions
  • Antimicrobial Peptides and Activities
  • Fish Biology and Ecology Studies
  • Invertebrate Immune Response Mechanisms
  • Plant Physiology and Cultivation Studies
  • Polyamine Metabolism and Applications
  • Probiotics and Fermented Foods
  • Amino Acid Enzymes and Metabolism

Central Institute of Fisheries Education
2016-2025

Indian Council of Agricultural Research
2020-2021

Sambalpur University
2021

Eastern New Mexico University
2009-2015

Karnataka Veterinary Animal and Fisheries Sciences University
2008-2012

Kasturba Medical College, Manipal
2012

Theodore Roosevelt High School
2009

K S Hegde Medical Academy
2005

Central Institute of Psychiatry
2005

University of Agricultural Sciences, Dharwad
2005

ABSTRACT A multidrug efflux pump designated LmrS (lincomycin resistance protein of Staphylococcus aureus ), belonging to the major facilitator superfamily (MFS) transporters, was cloned, and role in antimicrobial evaluated. The highest relative increase MIC, 16-fold, observed for linezolid tetraphenylphosphonium chloride (TPCL), followed by an 8-fold sodium dodecyl sulfate (SDS), trimethoprim, chloramphenicol. has 14 predicted membrane-spanning domains is homologous putative lincomycin...

10.1128/aac.00580-10 article EN Antimicrobial Agents and Chemotherapy 2010-09-21

Bacterial infections pose a serious public health concern, especially when an infectious disease has multidrug resistant causative agent. Such bacteria can compromise the clinical utility of major chemotherapeutic antimicrobial agents. Drug and harbor several distinct molecular mechanisms for resistance. agent efflux pumps represent mechanism The facilitator superfamily (MFS) is one largest groups solute transporters to date includes significant number bacterial drug pumps. We review recent...

10.1155/2013/204141 article EN cc-by International Journal of Bacteriology 2013-12-05

The community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become increasingly prevalent in both community and hospital settings. aim of this study was to determine the prevalence, molecular characteristics antibiotic resistance profiles CA-MRSA from community- hospital-associated infections a tertiary care Mangalore, India. Of 520 S. isolates, 362 were inpatients (IP) 158 outpatients (OP). One-hundred thirty-two MRSA isolates obtained 94 38 with complete clinical...

10.3390/antibiotics10020197 article EN cc-by Antibiotics 2021-02-18

Members of the family Enterobacteriaceae include several human pathogens that can be acquired through contaminated food and water. In this study, incidence extended spectrum β-lactamase (ESBL)-producing enterobacteria was investigated in fresh seafood sold retail markets. The ESBL-positive phenotype detected 169 (78.60%) isolates, with Escherichia coli being predominant species (53), followed by Klebsiella oxytoca (27), K. pneumoniae (23). More than 90% isolates were resistant to third...

10.3390/microorganisms5030053 article EN cc-by Microorganisms 2017-08-30

We cloned a gene, sugE, from the chromosome of Enterobacter cloacae ATCC 13047. Analysis susceptibilities sugE-containing strain (Escherichia coli KAM32/pSUGE28) and sugE-deficient E. (EcΔsugE) showed that SugE confers resistance to cetyltrimethylammonium bromide, cetylpyridinium chloride, tetraphenylphosphonium, benzalkonium ethidium sodium dodecyl sulfate. also investigated expression sugE. confirm here is an SMR family transporter as determined by observing its energy-dependent drug...

10.1128/aac.00094-11 article EN Antimicrobial Agents and Chemotherapy 2011-05-17

Diarrheal diseases are a major cause of morbidity and mortality in resource-limited countries. Among the bacterial pathogens, diarrheagenic E. coli (DEC) most frequently implicated cases epidemic endemic diarrhea worldwide. The objective this study was to determine prevalence DEC stool specimens from patients with acute using polymerase chain reaction (PCR).Escherichia samples were collected 115 hospitalized children adults Mangalore, coastal city, southern India. PCR amplification eae, bfp,...

10.4103/0974-2727.98666 article EN cc-by-nc-nd Journal of Laboratory Physicians 2012-01-01

All serotypes of Salmonella enterica are considered potentially pathogenic. However, the non-typhoidal (NTS) vary considerably in terms pathogenicity and severity infections. Although diverse NTS have been reported from tropical seafood, their sources, physiological characteristics, virulence potentials not well understood. This study aimed to compare characteristics selected serovars seafood investigate possible variations distribution known genes within islands.A series biochemical tests,...

10.14202/vetworld.2023.431-438 article EN cc-by Veterinary World 2023-03-01

The major facilitator superfamily (MFS) of proteins constitutes a large group related solute transporters found across all known living taxa organisms. the MFS contain an extremely diverse array substrates, including ions, molecules intermediary metabolism, and structurally different antimicrobial agents. First discovered over 30 years ago, represents important collection integral membrane transporters. Bacterial microorganisms expressing multidrug efflux pumps belonging to are considered...

10.1016/j.crmicr.2024.100248 article EN cc-by Current Research in Microbial Sciences 2024-01-01

Contamination of coastal-marine environment with multidrug-resistant Escherichia coli has resulted in such bacteria increasingly being detected the seafood chain. This study aimed to determine quinolone and colistin resistance genes extended spectrum-β-lactamase (ESBL)-producing E. from seafood. ESBL-producing isolates (n = 269) were tested for quinolones phenotypes by disk diffusion broth microdilution methods, respectively. The further PCR screened plasmid-mediated (PMQR) qnrA, qnrB, qnrS,...

10.3390/applmicrobiol5010003 article EN cc-by Applied Microbiology 2025-01-05
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