A5090173358- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Infection Control and Ventilation
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- COVID-19 Pandemic Impacts
- Immune cells in cancer
- COVID-19 epidemiological studies
- Blood disorders and treatments
- Venous Thromboembolism Diagnosis and Management
- MicroRNA in disease regulation
- HIV/AIDS Research and Interventions
- Inflammatory Biomarkers in Disease Prognosis
- S100 Proteins and Annexins
- Blood Coagulation and Thrombosis Mechanisms
- Circular RNAs in diseases
- Machine Learning in Healthcare
- Land Use and Management
- Clostridium difficile and Clostridium perfringens research
- Immunotherapy and Immune Responses
- Bacteriophages and microbial interactions
- Eosinophilic Disorders and Syndromes
- Data Quality and Management
- Diphtheria, Corynebacterium, and Tetanus
- Bacterial Infections and Vaccines
- Iron Metabolism and Disorders
Sechenov University
2021-2024
Omsk State Medical University
2020-2024
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
2023
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2023
Perm State University
2023
Quality Research
2023
State Research Center of Virology and Biotechnology VECTOR
2021
Belarusian State University
2021
Bogdan Khmelnitsky Melitopol State Pedagogical University
2011
We aimed to compare duration of uterine artery embolization, radiation exposure, safety and quality life associated with the procedure in patients undergoing embolization using transradial transfemoral access.This randomized controlled trial was conducted from February 2013 March 2017 three hospitals. Transradial access used 78 75 patients. Clinical characteristics were comparable between two groups. Patients evaluated for success procedure, major minor complications. Quality assessed among...
MicroRNAs (miRNAs) are small, non-coding RNAs that play an important role in regulating gene expression. Dysregulation of miRNA expression is commonly observed cancer, and it can contribute to malignant cell growth. Melanoma the most fatal type skin neoplasia. Some microRNAs be prospective biomarkers for melanoma stage IV (advanced) at higher risk relapses require validation diagnostic purposes. This work aimed (1) determine significant microRNA biomarker candidates using content analysis...
Introduction. Studies evidence about a relation between increased circulating free DNA (cfDNA) concentrations and chemotherapy, the majority of which have been focused on considering tumor as source cfDNA. It has suggested that neutrophils also contribute to this process, cancer-related cfDNA characteristics resemble those neutrophil extracellular traps (NETs). Therefore, elevated concentration observed in chemotherapy patients may be associated with NETosis. Aim: assessment NETosis markers...
The use of face masks has assumed a leading spot among nonspecific prevention measures during the coronavirus pandemic. effectiveness this protective measure depends on specifics individual use. purpose our study was to analyze respiratory equipment (RPE) by medical students COVID-19 evaluation mask based results survey at Sechenov University. There were 988 participants in study: 97.5% used RPE pandemic, 89.1% disposable and hygienic masks, 27.4% reusable cloth 13.2% respirators. majority...
Microbicides, which are classified as topical antiseptic agents, a revolutionary advancement in HIV prevention aimed to prevent the entry of infectious agents into human body, thus stopping sexual transmission and other sexually transmitted diseases. Microbicides represent promise new age preventive measures against one world’s most pressing health challenges. In addition their direct antiviral effects during transmission, microbicides also influence vaginal mucosal immunity. This article...
The COVID-19 outbreak represents a global public health emergency. National governments have gradually introduced restrictive measures. Using respiratory protective equipment (face masks) and gloves was essential practice without specific infection control measures or guidelines. This study aimed to assess hygiene indicators when using by transport workers in Russia during the pandemic develop integral recommendations for wearing whom this is mandatory requirement. For purpose, 1103 were...
(1) Background: The use of face masks and gloves in public places directly shows the commitment population to established regulations. Public transport is one most-at-risk contamination. aim study was analyze mask by passengers workers during COVID-19 pandemic. (2) Methods: were surveyed. Periodic intermittent selective observation used gauge level adherence regulations among passengers. Factor analysis identify factors determining face-mask-wearing comfort. (3) Results: majority (87.5%) all...
As of the end 2022, despite disruptions caused by COVID-19 pandemic, global HIV epidemic persists, with 39 million individuals living virus and 1.3 new infections reported in that year. Opportunistic associated AIDS claimed lives over 630,000 people contributing to a cumulative death toll exceeding 40.4 since disease's emergence 1981. Although advances diagnosis antiretroviral therapy have transformed disease into manageable chronic condition, issues like drug resistance, low...
Introduction. Neutrophil extracellular traps (NETs) and von Willebrand factor (vWF) are integral players in thrombosis inflammation cancer patients. It has been increasingly evident that an active interplay exists between NETs vWF. Some studies suggest cause decrease ADAMTS-13 (a disintegrin metalloprotease with thrombospondin type 1 motif, member 13) activity, being arm the pathogenesis of both thrombotic microangiopathies (TMA) other complications during oncological process. Aim: to assess...
Introduction. One of the leading causes in mortality pattern cancer patients is accounted for by thrombotic complications. Recent studies have shown that neutrophil extracellular traps (NETs) are involved activation coagulation, contribute to initiation and progression thrombosis. In addition, NET-related effect on tumor metastasis has been actively studied. Aim: evaluate procoagulant activity gynecological patients. Materials Methods. From April 2020 October 2022, a prospective controlled...
Due to the conditions that cause spread of COVID-19, national health systems worldwide are under severe strain. Most countries face similar difficulties such as a lack medical personnel and equipment tools for diagnosis treatment, overrun hospitals, forced restriction planned care. Public authorities in healthcare take following measures due increased pressure: limiting transmission virus (social distancing quarantine), mobilizing personnel, ensuring availability diagnostic treatment tools,...
The use of respiratory protection is one the measures for non-specific prophylaxis coronavirus infection. wearing masks mandatory entire population in several countries, including Russia. object study airport workers who are at an increased risk They contact with many passengers arriving from other countries where mass vaccination has not yet been carried out. aims to assess hygienic prevalence adverse reactions when using face masks, identify factors their occurrence. A questionnaire survey...
AIM: to improve late results of pilonidal disease treatment.PATIENTS AND METHODS: a multicenter retrospective cohort study included patients with using the original new method — main group (n = 31) and Karidakis as controls 70). The recurrence rate was estimated. Six months after surgery, ultrasound, Vancouver Scale SF-36 questionnaire assessed postoperative scar, cosmetic result quality life.RESULTS: effect scar evaluated significant differences between groups were obtained. According...
Despite more than 50 years of primary immunization against diphtheria, pertussis, and tetanus in Russia, complicated illnesses, including fatal ones, still occur. The goal this preliminary cross-sectional study is to see how well pregnant women healthcare workers are protected tetanus. required sample size (pregnant professionals, as two age categories) for was calculated using a confidence value 0.95 probability 0.05. number participants each group must be at least 59 people. In the Moscow...
Activation of NETosis processes has been detected in numerous autoimmune and non-autoimmune diseases with increasing concentrations antiphospholipid antibodies (APA). Neutrophil extracellular traps (NETs) are an important activator the coagulation cascade integral component arterial venous clots cancer patients. Therefore, APA NETs may be links pathogenesis thrombosis Objective. To evaluate severity NETosis, hemostatic system activation circulation (anti-β2-glycoprotein 1 (anti-β2-GPI))...
Immunothrombosis, tumor progression and metastasis are inextricably linked. These close interactions carried out by several actors. Neutrophils considered as players in the antimicrobial host defense. Activated neutrophils release extracellular traps (NETs) involved immune response pathogenesis of various conditions including growth. interleukin-8 (IL-8) play a key role formation NETs. Objective. To evaluate interaction between NETs IL-8, their contribution to development immunothrombosis...
The incidence of venous thrombosis in patients undergoing chemotherapy is high. Activation vascular endothelium during followed by elevated concentrations von Willebrand factor (vWF), decreased ADAMTS13, and increased thrombotic risk. Objective. To study the significance vWF:Ag ADAMTS13:Ag ratio to (VWF:Ag/ADAMTS13:Ag) as risk factors for gynecologic cancer chemotherapy. Patients methods. prospective controlled interventional non-randomized trial included 222 aged 34 72 years who underwent...
The novel coronavirus disease 2019 (COVID-19) pandemic has had a huge impact on all areas of human life. Since the risk biological threats will persist in future, it is very important to ensure mobilization readiness for prompt response possible emergence epidemics infectious diseases. Therefore, from both theoretical and practical standpoint, currently necessary conduct thorough examination COVID-19 epidemic. goal this research investigate underlying processes that led Russia identify ways...
A concept, method, algorithm, and computer system (CS) of step-by-step dialog optimization biomarker (BM) panels for assessing human biological age (BA) according to a number universal criteria based on incomplete noisy data have been developed. This provides the ability automatically build BM BA assessment increase accuracy determination while reducing measured BMs. The are as follows: high correlation BMs with chronological (CA); minimum size panels, obtained by rejecting highly...