A5002937079- Automotive and Human Injury Biomechanics
- Musculoskeletal pain and rehabilitation
- Photography and Visual Culture
- Spine and Intervertebral Disc Pathology
- Traffic and Road Safety
- Injury Epidemiology and Prevention
- Autopsy Techniques and Outcomes
- Spinal Fractures and Fixation Techniques
- Ethics and Legal Issues in Pediatric Healthcare
- Transportation Safety and Impact Analysis
- Medical Malpractice and Liability Issues
- Intimate Partner and Family Violence
- Children's Rights and Participation
- Agriculture and Farm Safety
- Southeast Asian Sociopolitical Studies
- Total Knee Arthroplasty Outcomes
- Osteoarthritis Treatment and Mechanisms
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Myofascial pain diagnosis and treatment
- Health and Conflict Studies
- Orthopedic Surgery and Rehabilitation
- Medical Imaging and Analysis
- 3D Surveying and Cultural Heritage
- Periodontal Regeneration and Treatments
- Child and Adolescent Health
Royal College of Physicians
2024
Maastricht University
2016-2024
Oregon Health & Science University
2011-2024
California Polytechnic State University
2024
Tufts University
2019-2022
University College London
1994-2020
Aarhus University
2006-2016
Umeå University
2012-2015
UCL Australia
1999-2015
National Museum Wales
2015
Children, Rights and Childhood by David Archard London : Routledge , 2004 ISBN 0415305845 246 pp £16.99 (pb) Eleven years separate this book from an earlier version of it. It is now much more substantial there greater emphasis on children's rights, with attention given to the UN Convention 1989. a philosopher it has characteristic that discipline: argument clear, well reasoned balanced. Philosophers can often offer insights even when they traverse relatively unexplored philosophical terrain:...
Mesenchymal stem cells (MSCs) hold great promise as therapeutic agents in regenerative medicine. Numerous animal studies have documented the multipotency of MSCs, showing their capabilities for differentiating into orthopedic tissues such muscle, bone, cartilage, and tendon. However, safety culture expanded MSC's human use has only just begun to be reported.Between 2006 2010, two groups patients were treated various conditions with culture-expanded, autologous, bone marrow-derived MSCs...
Introduction. We investigated the use of autologous bone marrow concentrate (BMC) with and without an adipose graft, for treatment knee osteoarthritis (OA). Methods. Treatment registry data patients who underwent BMC procedures graft were analyzed. Pre- posttreatment outcomes interest included lower extremity functional scale (LEFS), numerical pain (NPS), a subjective percentage improvement rating. Multivariate analyses performed to examine effects type adjusting potential confounding...
ABSTRUCT: Mesenchymal stem cells (MSCs) hold great promise as therapeutic agents in regenerative medicine. Numerous animal studies have documented the multipotency of MSCs, showing their capabilities for differentiating into orthopedic tissues such muscle, bone, cartilage, and tendon. However, complication rate autologous MSC therapy is only now beginning to be reported.Between 2005 2009, two groups patients were treated various conditions with culture-expanded, autologous, bone...
The purpose of the present investigation is to report on detailed complications among a much larger group 2372 orthopaedic patients treated with stem cell injections who were followed in treatment registry for up nine years. All underwent an MSC-based, percutaneous injection condition between December 2005 and September 2014 at one 18 clinical facilities. Treated areas body included knee, hip, ankle/foot, hand/wrist, elbow, shoulder, spine. prospectively via enrollment registry. Patients...
Degenerative disc disease (DDD) is a common cause of lower back pain with radicular symptoms and has significant socioeconomic impact given the associated disability. Limited effective conservative therapeutic options result in many turning to surgical alternatives for management, which vary rate success also carry an increased risk morbidity mortality procedures. Several animal based studies few human pilot have demonstrated safety suggest efficacy treatment DDD mesenchymal stem cells...
The native envelope (Env) spike on the surface of human immunodeficiency virus type 1 (HIV-1) is trimeric, and thus trimeric Env vaccine immunogens are currently being explored in preclinical immunogenicity studies. Key challenges have included production purification biochemically homogeneous stable trimers evaluation these utilizing standardized panels for neutralization assays. Here we report binding neutralizing antibody (NAb) responses elicited by clade A (92UG037.8) C (CZA97.012) gp140...
Prior studies describing the treatment of symptomatic knee osteoarthritis with injections bone marrow concentrate have provided encouraging results. The relationship between cellular dose contained within and efficacy treatment, however, is unclear. In present study we describe clinical outcomes for in relation to higher lower cell concentrations a protocol. Data from an ongoing patient registry was culled identify 373 patients that received 424 osteoarthritic joints. scales these were...
Shoulder pain is a common musculoskeletal complaint in the general population. Bone marrow concentrate (BMC) injections offer promising potential as minimally invasive approach for treatment of shoulder degenerative disease. In this study, we investigated clinical outcomes BMC and disability due to osteoarthritis (OA) rotator cuff tears registry population.A total 115 shoulders 102 patients were treated with autologous symptomatic OA at glenohumeral joint and/or tears. Data collected factors...
This was a prospective case series designed to investigate treatment for anterior cruciate ligament (ACL) tears using an injection of autologous bone marrow concentrate.Consecutive adult patients presenting private outpatient interventional musculoskeletal and pain practice with knee pain, ACL laxity on exam, magnetic resonance imaging (MRI) evidence grade 1, 2, or 3 less than 1 cm retraction were eligible this study. Eligible treated intraligamentous concentrate, fluoroscopic guidance. Pre-...
The two publications of the Quebec Task Force on Whiplash-Associated Disorders were evaluated by authors this report for methodologic error and bias.To determine whether conclusions recommendations regarding natural history epidemiology whiplash injuries are valid.In 1995, authored a text (published Societe de l'Assurance Automobile du Quebec) pullout supplement in Spine entitled "Whiplash-Associated Disorders: Redefining Whiplash its Management." concluded that result "temporary...
Epidural steroid injections (ESI) are the most common pain management procedure performed in US, however evidence of efficacy is limited. In addition, there early that high dose corticosteroids used can have systemic side effects. We describe results a case series evaluating use platelet lysate (PL) epidural for treatment lumbar radicular as an alternative to corticosteroids.Registry data was obtained patients (N = 470) treated with PL presenting symptoms and MRI findings were consistent...
It has been established that chronic neck pain following whiplash is associated with the phenomenon of central sensitization, in which injured and uninjured parts body exhibit lowered thresholds due to an alteration processing. it furthermore hypothesized peripheral sources nociception muscles may perpetuate sensitization whiplash. hypothesis explored present study was whether myofascial trigger points serve as a modulator subjects pain.Controlled case series.Outpatient clinic.Seventeen...
Abstract Background Cell-based therapies have shown promise for the treatment of knee osteoarthritis (OA). The current study compared exercise therapy to autologous bone marrow concentrate (BMC) and platelet products OA treatment. Methods Patients with symptomatic (N = 48) were randomized into either an control group or injection BMC products. in could crossover after 3 months. Clinical outcomes documented at baseline 6-weeks, 3, 6, 12 24 months, including Knee Society Score (KSS), Pain...