A5101619920- Colorectal Cancer Surgical Treatments
- Copper Interconnects and Reliability
- Cancer Immunotherapy and Biomarkers
- Mesenchymal stem cell research
- Colorectal and Anal Carcinomas
- Osteoarthritis Treatment and Mechanisms
- Bone Tissue Engineering Materials
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Metal and Thin Film Mechanics
- RNA modifications and cancer
- Gold and Silver Nanoparticles Synthesis and Applications
- Ferroptosis and cancer prognosis
- Advanced Sensor and Energy Harvesting Materials
- Berberine and alkaloids research
- Antifungal resistance and susceptibility
- Carbon and Quantum Dots Applications
- Marine Biology and Environmental Chemistry
- Circular RNAs in diseases
- Nanomaterials and Printing Technologies
- Copper-based nanomaterials and applications
- Heat Transfer and Boiling Studies
- Anodic Oxide Films and Nanostructures
- Power Systems and Renewable Energy
- Material Properties and Processing
Fujian Medical University
2019-2025
Union Hospital
2020-2025
Shanghai Jian Qiao University
2024
Chongqing Three Gorges University
2024
Chongqing University
2024
Harbin Institute of Technology
2024
Lanzhou University of Technology
2023-2024
Sun Yat-sen University
2021-2023
Sun Yat-sen University Cancer Center
2021-2023
Affiliated Hospital of Hebei University
2022-2023
The multilineage differentiation potential of adult tissue-derived mesenchymal progenitor cells (MPCs), such as those from bone marrow and trabecular bone, makes them a useful model to investigate mechanisms regulating tissue development regeneration, cartilage. Treatment with transforming growth factor-beta (TGF-beta) superfamily members is key requirement for the in vitro chondrogenic MPCs. Intracellular signaling cascades, particularly involving mitogen-activated protein (MAP) kinases,...
A desirable strategy for articular cartilage repair is to surgically replace the damaged area with an in vitro-engineered osteochondral plug. We report here development of a novel construct using human trabecular bone-derived mesenchymal progenitor cells and biodegradable poly-D,L-lactic acid scaffold. The layer was fabricated by press-coating chondrifying high-density cell pellet onto scaffold, which then loaded previously initiated undergo osteogenesis. composite cultured cocktail medium...
Abstract In this study, we used nitrogen-doped carbon dots (NCDs), which were synthesized via the hydrothermal method of corn-stover biomass as raw material and polyethyleneimine nitrogen source, introduced them into carboxymethyl cellulose (CMC)-based hydrogel to prepare an environmentally friendly fluorescent cellulose-based (NCDs/CMC-PAM). NCDs/CMC-PAM was also for simultaneous fluorescence monitoring removal Cu (II) in aqueous solution. The chemical physical structures, adsorption...
Conductive hydrogels with high electrical conductivity, ductility, and anti-dryness have promising applications in flexible wearable electronics. However, its potential such a developing field are severely hampered by extremely poor adaptability to cold or hot environmental conditions. In this research, an "organic solvent/water" composite conductive hydrogel is developed introducing binary organic solvent of EG/H2O into the system using simple one-pot free radical polymerization method...
The emergence of resistant Candida albicans has made clinical fluconazole (FLC) treatment difficult. Improving sensitivity to FLC is an effective way treat isolates. Berberine hydrochloride (BBH) a commonly-used traditional Chinese medicine with antimicrobial effects, especially in We investigated the molecular mechanisms underlying BBH and synergism on biofilm-positive FLC-resistant C. inhibition. Checkerboard microdilution assays time-kill showed strong synergistic effect between isolates,...
Objective: To investigate the clinical application value of bundled nursing care in postoperative recovery lung cancer patients. Methods: Eighty patients who underwent surgical treatment from October 2022 to May 2024 were selected as study subjects. Their data retrospectively analyzed and grouped by methods. The group (n = 40) received care, while conventional routine care. Lung function, immune complication rate, pain level, exercise tolerance, quality life compared between two groups....
Ferroptosis plays an important role in the development of acute myeloid leukemia (AML); however, exact ferroptosis-related genes prognosis AML patients is unclear. RNA sequencing data and clinicopathological characteristics were obtained from The Cancer Genome Atlas database, FerrDb database. Cox regression analysis least absolute shrinkage selection operator performed to identify gene signatures. Gene Ontology (GO), Kyoto Encyclopedia Genes Genomes (KEGG), single-sample set enrichment...
Compositions, surface morphologies and mechanical properties of a novel designed TiNi/Ag bi-layer film grown by DC magnetron sputtering at various processes have been investigated. Ar pressure power had significant effects on quality composition films. The processed under high (0.36 Pa) was porous, while better density films can only be obtained low (0.12 Pa). adjusted power. load-displacement curves show the multiple "pop-ins"along nanoindentation loading, as indentation depth does not...
The filamentous fungus Trichoderma reesei is one of the most important fungi for production cellulases and xylanases, which can be used biofuel from lignocellulose. We aimed to develop an effective selection marker system more extensive functional genomic studies in T. reesei, construct better industrial transformants producing cellulases. Here, we present a novel G418 use codon-optimized neomycin phosphotransferase II gene nptII transform reesei. developed erasable marker, lcNG, combined...
Copper-zirconium bulk alloy and Cu-Zr films are prepared by vacuum smelting magnetron sputtering, respectively, subsequently annealing is conducted. Results show that exhibit significantly different microstructure evolution behaviors after due to microstructures residual stress states. CuxZr compounds disperse at the grain boundary of Cu grains in as-cast annealed alloys. However, unlike alloys, a large number polyhedral particles formed on thin films' surface upon thermal annealing....
Copper–chromium alloy film and Cu–Cr bulk were obtained using magnetron sputtering vacuum smelting. Experimental results indicated that films having different residual stress atomic diffusion exhibit a significant difference in microstructure evolution behaviors after annealing. Numerous polyhedral Cu particles dendritic Cr precipitated on the surface of annealed as–cast alloy, respectively. formed under driving energy film. The effect annealing temperature content size quantity is...
Abstracts Background Preclinical studies suggest that glucocorticoids (GCs) promote the proliferation and development of colorectal cancer. Because GCs are broadly prescribed for treatment-related adverse events in patients with locally advanced rectal cancer (LARC) receiving neoadjuvant chemoradiotherapy (NCRT), it’s essential to assess effect on clinical outcomes. Methods LARC cases treated NCRT followed by surgery were assessed retrospectively. Evaluation relationship between use (GCs vs....
Background The survival time of patients with early pancreatic cancer (PC) is still disappointing, even after surgical resection. PC has an extremely poor prognosis. Herein, we aimed to investigate the effect postoperative radiotherapy (PORT) on resected stage I II PC. Material and methods A large eligible sample was identified from 2010 2015 Surveillance, Epidemiology, End Results (SEER) registry. Survival analysis conducted evaluate efficiency PORT. Propensity score matching (PSM) used...
Purpose: To evaluate the effect of an intensified capecitabine and oxaliplatin (XELOX) chemoradiation treatment followed by one cycle consolidation chemotherapy before surgery in locally advanced rectal cancer (LARC). Methods Materials: Patients with histologically confirmed, newly diagnosed, adenocarcinoma (cT3-T4 and/or cN+) were enrolled. All patients received 3-dimensional conformal radiotherapy (3D-CRT) or intensity-modulated (IMRT) a dose 50.4Gy 25 fraction, two cycles concurrent XELOX...
Introduction The question of how to administer adequate chemotherapy synchronise stereotactic body radiation therapy (SBRT) treatment strategy maximise the benefits neoadjuvant for improved prognosis patients with borderline resectable (BRPC) and locally advanced (LAPC) pancreatic cancer is a challenging debatable issue. No studies have yet evaluated efficacy split-course SBRT as chemoradiotherapy regimen. We aimed study whether plus results in better outcomes BRPC LAPC patients. Methods...