A5101993701- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Catalytic C–H Functionalization Methods
- Axial and Atropisomeric Chirality Synthesis
- Research studies in Vietnam
- Molecular spectroscopy and chirality
- Catalytic Alkyne Reactions
- Asymmetric Hydrogenation and Catalysis
- Chemistry and Chemical Engineering
- Nanomaterials for catalytic reactions
- Catalytic Cross-Coupling Reactions
- Synthesis and Catalytic Reactions
- Nanotechnology research and applications
- Asymmetric Synthesis and Catalysis
- Crystallography and molecular interactions
- Synthesis of Indole Derivatives
- Thermodynamic properties of mixtures
- Spectroscopy and Quantum Chemical Studies
- Metabolomics and Mass Spectrometry Studies
- Medical Research and Treatments
- Analytical Chemistry and Chromatography
- Nanoparticles: synthesis and applications
- Alkaloids: synthesis and pharmacology
- Click Chemistry and Applications
- Synthetic Organic Chemistry Methods
Hanyang University
2019-2024
VNU University of Science
2024
Vietnam National University, Hanoi
2024
Korea Institute of Science and Technology
2024
Nong Lam University Ho Chi Minh City
2023
Anyang University
2019
Seoul Institute
2019
Texas Tech University
2016
1,3-Enynamides underwent oxygenative coupling with carbon- and heteroatom nucleophiles high remote selectivity. Kinetic analysis revealed a continuum mechanism between concerted S<sub>N</sub>2′′ via carbocation, depending on the used.
Determining the chirality of phosphoric acids can be a challenging task. In this study, we present novel approach for chiral recognition phosphates using cationic octahedral cobalt complexes. By utilizing 31P NMR spectroscopy, are able to accurately measure enantiopurities after forming ion pairs with We have successfully applied method variety derived from BINOL, H8-BINOL, SPINOL, VAPOL, and VANOL compounds, as well ATP, were efficiently resolve them in 31P{1H} spectra. Furthermore, achieve...
An enantioselective Cu(I)-catalyzed coupling of N-carboxyindoles with various 2-naphthols and phenols for the synthesis axially chiral arylindoles has been developed. Our mechanistic studies, bolstered by experimental evidence DFT calculations, reveal a novel closed-shell mechanism involving outer-sphere attack on Cu-bound naphthols. This allows unprecedented diversity in C-H arylation. Enantiocontrol is achieved through center-to-axis chirality transfer via key dearomatized naphthol...
Control over chemo- and regioselectivity is a critical issue in the heterobiaryl synthesis via C–H oxidative coupling. To address this challenge, strategy to invert normal polarity of indoles was developed.
Despite significant advances in the C-H/C-H coupling for synthesis of axially chiral indolylaryl compounds, control over chemo-, regio-, and atropselectivity remains a challenge. We introduce herein N-carboxyindoles as an electrophilic partner that couple with range 2-naphthols phenols highly chemo- enantioselective manner (up to 96:4 er). Deuterium exchange in-situ 1H NMR spectroscopy supports chirality is generated transferred via dearomatized naphthol intermediates. Experiments radical...
Oxidation of ynamides by mCPBA led to β-oxygenation and resulted in formation carbonyl compounds with α-N,O-acetal functionality. These N,O-acetals are formed high yields can be stored indefinitely at room temperature. Yet, they activated a chiral Brønsted acid underwent an enantioselective transacetalization into α-N,O-acetal. Subsequent diastereoselective transformations occurred exceptional selectivity according Felkin-Anh model.
We present simple %-level accuracy universal correlations for densities of aqueous electrolyte solutions at 298.15 K and 0.1 MPa. The developed expressions parameters are based on 1032 experimental density data points 56 single including chlorides, bromides, iodides, bicarbonates, carbonates, sulfates, nitrates, nitrites, phosphates, hydrogen dihydrogen phosphates. relate the solution with "excess" mass fraction electrolytes in solution. With molar concentrations as input, correlation yields...
Abstract The study was to investigate the possibility of synthesizing silver nanoparticles by chemical reduction method using Syzygium Samagense flower bud extract as a green reducing agent. Various reaction conditions affecting synthesis were investigated including AgNO 3 concentration (2 mM; 5 10 mM), volume ratio V /V AgNO3 (2:30; 3:30; 4:30; 5:30), temperature (50 – 80 °C), time (15 - 60 mins). presence detected combination spectroscopy and X-ray diffraction (XRD) technology while size...
The development of efficient and sustainable chemical processes which use greener reagents solvents, currently play an important role in current research. Methanol, a cheap readily available resource from industry, could be activated by transition metal catalysts. This review provides systematic summary strategies for methanol activation the organic chemistry. Based on these strategies, many new synthetic methods have been developed utilization as C1 building block methylation,...
Đặt vấn đề: Dựa trên các ưu điểm của peptid kháng khuẩn tự nhiên, cation lưỡng phần phân tử nhỏ hiện đã và đang được coi là một hướng nghiên cứu phát triển thuốc tiềm năng, giúp tìm ra hoạt chất mới có tác dụng nấm. đặc cấu trúc lõi nhóm lựa chọn khung 1,3,4oxadiazol bộ xuất trong nhiều hợp tính để thiết kế, tổng khảo sát khuẩn, Mục tiêu cứu: Tổng dẫn hexyloxyphenyl-1,3,4-oxadiazol thử nấm được; Đối tượng phương pháp Dẫn từ nguyên liệu ban đầu 4-hydroxybenzaldehyd thông qua bốn bước: O-alkyl...
N,O-Acetals obtained from β-oxidation of ynamides underwent transacetalization with benzotriazoles, leading to N,N-acetals. The Zn(OTf)2 efficiently catalyzed the process, and reaction is further accelerated in hexafluoroisopropanol, providing a single N1-regiosiomer. conditions developed could be extended other N-donors, such as 1H-indazole TMSN3 afford corresponding
Nghiên cứu mô tả cắt ngang sử dụng phương pháp hồi số liệu có sẵn của tất cả (63.363) bệnh nhân điều trị dự phòng dại sau phơi nhiễm thuộc Dự án Khống chế và loại trừ – Bộ Y tế nhằm một đặc điểm dịch tễ học tại khu vực Tây Nguyên giai đoạn 2016 2020. Trong này, ca cao nhất vào năm 2018 đó giảm dần. Số lượng tăng từ tháng 3 đến 8. Tỷ lệ trẻ em dưới 15 tuổi người lớn 25 49 phải (31,5% 35,6%). Chó là động vật gây chủ yếu cho (91,3%), gần 80% ở trạng thái bình thường. Hầu hết(88,9%) dân ý thức...
Nghiên cứu mô tả cắt ngang này sử dụng phương pháp hồi số liệu có sẵn của tất cả (54) ca tử vong thuộc Dự án Khống chế và loại trừ bệnh dại – Bộ Y tế nhằm thực trạng do ở người tại khu vực Tây Nguyên giai đoạn 2016 2020. Kết quả cho thấy gia tăng liên tục qua các năm. Tỷ lệ nam giới cao hơn nữ (70,4% 29,6%), nhóm dân tộc thiểu (63,0%) từ 15 tuổi trở lên (57,4%). Nguồn truyền chủ yếu là chó (75,9%) 20,4% động vật cắn bị tình bình thường. Thời gian ủ 1 đến 3 tháng (31,5%). Chỉ 13% nhân được xử...