A5072140666- Veterinary Orthopedics and Neurology
- Fetal and Pediatric Neurological Disorders
- Veterinary Equine Medical Research
- Cerebrospinal fluid and hydrocephalus
- Metabolism and Genetic Disorders
- Spinal Dysraphism and Malformations
- Diet and metabolism studies
- Veterinary Oncology Research
- Neurological diseases and metabolism
- Hip disorders and treatments
- Parasitic Infections and Diagnostics
- Toxoplasma gondii Research Studies
- Teratomas and Epidermoid Cysts
- Hedgehog Signaling Pathway Studies
- Craniofacial Disorders and Treatments
- Head and Neck Surgical Oncology
- Spine and Intervertebral Disc Pathology
- Glioma Diagnosis and Treatment
- History and advancements in chemistry
- Infant Health and Development
- Neuroinflammation and Neurodegeneration Mechanisms
- Virus-based gene therapy research
- Amino Acid Enzymes and Metabolism
- Neuroendocrine regulation and behavior
- Congenital Anomalies and Fetal Surgery
Cornell University
2015-2025
New York State College of Veterinary Medicine
2016-2025
Southampton Children's Hospital
2023
Southampton General Hospital
2023
Royal Veterinary College
2008-2022
University of York
2017
Newmarket Equine Hospital
2015-2016
Veterinary Medical Teaching Hospital
2015
University of Leeds
2014
Association of British Paediatric Nurses
2013
Abstract Despite appropriate antiepileptic drug treatment, approximately one-third of humans and dogs with epilepsy continue experiencing seizures, emphasising the importance for new treatment strategies to improve quality life people or epilepsy. A 6-month prospective, randomised, double-blinded, placebo-controlled cross-over dietary trial was designed compare a ketogenic medium-chain TAG diet (MCTD) standardised placebo in chronically drug-treated idiopathic Dogs were fed either MCTD 3...
Adult dogs with neosporosis can develop a variety of neurologic signs. No area predilection within the nervous system so far has been identified in adult dogs.To document as cause progressive cerebellar ataxia and atrophy dogs.Seven client-owned dogs.Retrospective, descriptive study.Age at diagnosis ranged from 1 year 6 months to 9 years 11 months. Neuroanatomic localization indicated brainstem disease central vestibular lesion dog. In all 7 dogs, there was moderate marked bilaterally...
This report describes a cat with chronic, progressive, non-painful, non-lateralizing multifocal neurologic clinical signs associated feline infectious peritonitis (FIP). The initially presented as underweight, despite good appetite, and complete blood count showed non-regenerative anemia. Three months later the was returned having developed ataxia paraparesis, which then progressed over 2 to tetraparesis, tail plegia, urinary fecal incontinence, titubation. Histologic examination of tissues...
Clinical characteristics of cervical hydrated nucleus pulposus extrusion (HNPE) in dogs compared to other causes myelopathy are not well described. To evaluate for clinical and mechanical ventilation likelihood associated with HNPE myelopathy. Three hundred seventy-seven client-owned from 2010 2022. Cases included 46 HNPE, 192 IVDE (intervertebral disc extrusion), 30 FCEM (fibrocartilaginous embolic myelopathy), 66 CSM (cervical spondylomyelopathy), 43 neoplasia. Retrospective study record...
Abstract Background Inflammatory processes may play an important role in cognitive decline and dementia. We investigated the prospective association between levels of three markers inflammation, plasma interleukin‐6 (IL‐6), serum C‐reactive protein (CRP), amyloid A (SAA), African‐Caribbean community population. Methods Of 290 participants aged 55–75 years at baseline sampled from Primary Care registration lists south London, 216 (75%) were re‐interviewed after 3 years. Baseline...
To report use of ventriculoperitoneal shunt in dogs for management hydrocephalus which no cause could be identified. Case series. Dogs with (n=12). Medical records (June 2003-June 2009) were reviewed to determine preoperative clinical findings, initial postoperative, and long-term outcome. Additional follow-up information was obtained from owners referring veterinarians. All had signs forebrain dysfunction, 7 vestibular 3 spinal pain. Postoperative complications included pain (n=4),...
Neosporosis is a polysystemic disease that can affect dogs of any age and cause inflammation the central nervous system. Antemortem diagnosis be challenging, as clinical conventional laboratory test findings are often nonspecific. A previous report described cerebellar lesions in brain MRI studies seven proposed these may characteristic for system Neosporosis. The purpose this retrospective study was to describe characteristics another group with confirmed neosporosis compare them report....
Complete assessment of vertebral trauma in dogs currently requires CT and MRI for evaluation the osseous soft tissue structures that contribute to stability. Some studies people have suggested may be sensitive specific at detecting fractures making this potentially a single modality could used spinal evaluation. This study aimed assess ability observers evaluate using when compared CT, which was as reference standard. Twenty-nine with previously diagnosed acute four no fracture had undergone...
A retrospective study was performed to identify dogs with cerebrospinal fluid-filled cavitatory lesions on MRI. Six were included and the classified. In three in present hydranencephaly, unilateral but complete loss of temporal parietal lobes noted had almost occipital frontal a cerebral hemisphere. porencephaly, there incomplete lobe one dog additional partial lobes. Two porencephaly seizures; third showed no associated clinical signs. The hydranencephaly mentation changes circled...
Objective To report challenges and complications associated with surgical intracranial epidermoid cyst removal from the fourth ventricle of a dog. Study Design Clinical report. Animal Labrador retriever (7 years old) focal seizures. Methods Magnetic resonance imaging ( MRI ) revealed an oval lesion in ventricle. This was heterogeneously hyperintense on T 2‐weighted fluid attenuation inversion recovery FLAIR images hypointense 1‐weighted images. Dilatation ventricular system present. A...
A nine-month-old puppy was presented for investigation of seizures. Neurological deficits were found localising to the prosencephalon, mesencephalon and myelencephalon. Magnetic resonance imaging identified multiple, large lesions involving both cerebral hemispheres. Management with antiepileptic immunomodulatory drugs instituted; however, seizures became progressively refractory euthanased. Histopathology following post-mortem examination a mixed glial cell tumour discrete areas where...
This study investigated the cross sectional area (CSA) and fat infiltration of epaxial muscles in Dachshunds with compressive spinal cord lesions due to intervertebral disc herniation (IVDH) dogs non-compressive fibrocartilaginous embolism (FCE). The CSA multifidi longissimus dorsi were determined from T1 weighted magnetic resonance images. Difference between lesion- non-lesion side was assessed using mixed model analysis. FCE analysed independent sample t-tests. There no difference or sides...
To practice evidence-based medicine, clinicians must be competent in information literacy (IL). Few studies acknowledge the critical role that reading strategies play IL instruction and assessment of health professional students. The purpose this study was to understand information-seeking evaluation behaviors doctor veterinary medicine (DVM) students regard scientific papers.The authors studied DVM student across eight programs North America using a web-based survey closed- open-ended...
Clinical summary: A 4-year-old Birman cat was presented with marked obtundation and non-ambulatory tetraparesis. Two well-demarcated, intra-axial T2-hyperintense, T1-hypointense structures, which did not contrast enhance, were evident on magnetic resonance imaging (MRI). Histopathology of the structures revealed metacestodes that morphologically indicative larval stages Taenia species. Polymerase chain reaction amplification a fragment within 12S rRNA gene confirmed subspecies as serialis....
Déjà vu is typically a transient mental state in which novel experience feels highly familiar. Although extensively studied relation to temporal lobe epilepsy as part of simple partial seizures, déjà has been less other clinical populations. A recent review suggested possible link between levels anxiety and debilitating vu, indicating further research required. Here, for the first time literature, we present case study young man with depersonalisation who reported experiencing persistent vu....
Spontaneous brain microhemorrhages in elderly people are present to some degree Alzheimer's disease patients but have been linked atrophy the absence of obvious cognitive decline. Brain recently described older dogs, it is unclear whether these associated with atrophy. Diminution interthalamic adhesion size-as measured on MRI or CT-has shown be a reliable indicator dogs canine dysfunction (CCD) comparison successfully aging dogs. We hypothesized that presenting for neurologic without...
Feline tail pull injury is a challenging condition that commonly encountered in first‐opinion practice. This article discusses the key factors diagnosis, prognosis and management of injuries, including use radiography to confirm sacrocaudal luxation, identification appropriate treatment associated urinary faecal dysfunction. It also highlights importance good owner communication, as currently best prognostic indicators at time presentation for return continence (the conscious perception...
Emma Davies, early years teacher and founder of Is it Time to Play? argues that the term ‘childcare’ is damaging perceptions education instead our language should recognise vital role practitioners play as educators.