- Rheumatoid Arthritis Research and Therapies
- Musculoskeletal synovial abnormalities and treatments
- Spondyloarthritis Studies and Treatments
- Urticaria and Related Conditions
- Bone and Joint Diseases
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Gout, Hyperuricemia, Uric Acid
- Autoimmune and Inflammatory Disorders Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Medical Imaging and Pathology Studies
- Orthopedic Infections and Treatments
- Systemic Sclerosis and Related Diseases
- Osteoarthritis Treatment and Mechanisms
- Orthopedic Surgery and Rehabilitation
- Neuroendocrine Tumor Research Advances
- Total Knee Arthroplasty Outcomes
- Skin Diseases and Diabetes
- Neurofibromatosis and Schwannoma Cases
- Dermatologic Treatments and Research
- Inflammatory mediators and NSAID effects
- Osteomyelitis and Bone Disorders Research
- Viral Infections and Immunology Research
- Bone health and treatments
- Alkaline Phosphatase Research Studies
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo
2022
University of Genoa
2004-2020
Università Cattolica del Sacro Cuore
2011
Teikyo University Chiba Medical Center
2008
Abstract This dynamic magnetic resonance imaging (MRI) study is concerned with a prospective evaluation of wrist synovitis in patients psoriatic arthritis (PsA) comparison rheumatoid (RA) and healthy controls. Fifteen consecutive PsA, 49 RA, 30 RA matched for disease severity those 8 controls were studied. MRI was performed low-field (0.2T), extremity-dedicated machine. After an intravenous bolus injection gadolinium-diethylenetriaminepentaacetic acid, 20 fast spin-echo axial images the...
the mainstay of treatment polymyalgia rheumatica (PMR) is oral glucocorticoids, but randomized controlled trials are lacking. As a result, there no evidence from studies on efficacy different initial doses or glucocorticoid tapering. The aim this study to test if 12.5 mg prednisone/day an adequate starting dose in PMR and evaluate clinical predictors drug response. 60 consecutive patients were treated with 12,5 mg/day prednisone. Clinical, laboratory, and, subset 25 patients,...
<h3>Objective.</h3> Dynamic, contrast-enhanced magnetic resonance imaging (DCE-MRI), the quantification of enhancement within synovial membrane and bone by extracting curves using fast T1-weighted sequences during intravenous administration contrast agent, evaluates synovitis marrow edema in psoriatic arthritis (PsA). In this pilot study, we looked at possible differences between joint tenosynovitis PsA as compared with rheumatoid (RA). <h3>Methods.</h3> Seven patients 10 RA were studied....
Abstract: Polymyalgia rheumatica (PMR) has a marked preponderance in women. The female sex been claimed to be risk factor for longer‐course corticosteroid therapy and associated with more severe systemic symptoms lower hemoglobin levels. Eighty consecutive patients affected by PMR, seen at two tertiary referral centers, were followed‐up mean period of 14.9 months after initiating treatment. At presentation, women had longer disease duration levels (both P = 0.05) than men. In contrast, their...
To study with MRI the hands of consecutive PMR patients, who were not selected on basis peripheral arthritis, a correlation to clinical and laboratory findings.Twenty-six 15 patients 26 13 healthy controls studied by extremity-dedicated for presence synovitis, tenosynovitis, soft-tissue oedema, bone marrow oedema erosions.Sixteen (61.6%) 4 (15.4%) control showed tenosynovitis (P = 0.001). Extensor tendon was seen in 9 (34.6%) hands, but only 1 (3.8%) hand 0.002) flexor 12 (46.1%) 0.03). All...
Objectives: MRI has been proposed as the imaging method of choice to evaluate long-term outcome in patients with early arthritis. The role dynamic MRI, performed at presentation, predicting arthritis addressed present study. Methods: 39 arthritis, involving least one wrist, were studied clinical visits and laboratory investigations, every 3 months. Dynamic was a low-field (0.2T), extremity-dedicated machine (Artoscan, Esaote, Genova, Italy) equipped permanent magnet dedicated hand wrist...
To evaluate if fulfilment of the definition osteoarthritis (OA) based on American College Rheumatology (ACR) clinical criteria corresponds to pathological knee findings evaluated by magnetic resonance imaging (MRI). any such is associated with a specific MRI pattern.Forty-six consecutive patients aged 50 years or more referred their general practitioners (GPs) radiology department because non-traumatic pain underwent using dedicated low field (0.2 T) machine.MRI results were compared against...
Modern imaging techniques are becoming increasingly important in assessing the course of arthritis and permitting measurement response to treatment as part follow-up patients. They include ultrasonography (US), MRI, PET/CT, biofluorescence. In patients with rheumatoid arthritis, clinical evaluation is significantly less sensitive than either US or MRI detecting synovitis. As a result, useful alternative achieving proper assessment disease activity. The different areas which new could help...
Modern imaging techniques are becoming increasingly important in assessing the course of arthritis and permitting measurement response to treatment as part follow-up patients. They include ultrasonography (US), MRI, PET/CT, biofluorescence. In patients with rheumatoid arthritis, clinical evaluation is significantly less sensitive than either US or MRI detecting synovitis. As a result, useful alternative achieving proper assessment disease activity. The different areas which new could help...
This open-label study evaluated the effects of combined tocilizumab (TCZ) and disease-modifying antirheumatic drugs (DMARDs) on magnetic resonance imaging (MRI) changes in synovial membrane enhancement, bone marrow edema (BME), erosions wrist hand joints rheumatoid arthritis (RA) patients inadequately responding to DMARDs alone.The efficacy intravenous TCZ 8 mg/kg administered every four weeks for 48 was six occasions. The primary endpoints were extent degree synovitis as measured using RA...
<h3>Background</h3> Dynamic, contrast-enhanced MRI (DCE-MRI), the quantification of enhancement within synovial membrane and bone by extracting curves using fast T1-weighted sequences during intravenous administration contrast agent, is useful to evaluate synovitis marrow edema in arthritis. <h3>Objectives</h3> In this pilot study, we looked at possible differences between joint tenosynovitis psoriatic arthritis (PsA) as compared with rheumatoid (RA). <h3>Methods</h3> Seven patients PsA 10...
Sternocostoclavicular hyperostosis (SCCH), a rare, benign disorder, is frequently associated with skin lesions, but can occur without them. Patients showing only bone lesions initially may later develop cutaneous symptoms. A 24-year-old white woman was referred for investigation of chronic pain and tenderness the sternocostoclavicular region minimal soft tissue swelling. The started 1 year before history trauma, low back pain, or arthritis. Examination did not reveal acne, palmoplantar...