A5057375556- Cell Adhesion Molecules Research
- Heme Oxygenase-1 and Carbon Monoxide
- Monoclonal and Polyclonal Antibodies Research
- HER2/EGFR in Cancer Research
- Plant Pathogens and Fungal Diseases
- Light effects on plants
- Adipose Tissue and Metabolism
- Wastewater Treatment and Nitrogen Removal
- Mycorrhizal Fungi and Plant Interactions
- Cellular Mechanics and Interactions
- Legume Nitrogen Fixing Symbiosis
- Retinoids in leukemia and cellular processes
- Cellular transport and secretion
- Inflammasome and immune disorders
- Peroxisome Proliferator-Activated Receptors
- Plant nutrient uptake and metabolism
- Cancer Treatment and Pharmacology
- Plant-Microbe Interactions and Immunity
- PI3K/AKT/mTOR signaling in cancer
- Cholesterol and Lipid Metabolism
- Eicosanoids and Hypertension Pharmacology
- Lipid Membrane Structure and Behavior
- Breast Cancer Treatment Studies
- Plant Pathogenic Bacteria Studies
- Cancer-related molecular mechanisms research
Universidad Nacional de La Plata
2019-2023
Consejo Nacional de Investigaciones Científicas y Técnicas
2014-2023
Instituto de Biotecnología y Biología Molecular
2023
University of Buenos Aires
2012-2022
Fundación Ciencias Exactas y Naturales
2016-2022
Biochemistry Research Institute of La Plata
2019-2020
Centro Científico Tecnológico - La Plata
2019-2020
National University of Luján
2012-2018
// Geraldine Gueron 1 , Jimena Giudice 2 Pia Valacco 3 Alejandra Paez Belen Elguero , Martin Toscani Felipe Jaworski Federico Coluccio Leskow Javier Cotignola Marcelo Marti Maria Binaghi Nora Navone 4 Elba Vazquez Department of Biological Chemistry, School Sciences, University Buenos Aires, IQUIBICEN-CONICET, Intendente Guiraldes 2160, CABA Pathology and Immunology, Baylor College Medicine, One Plaza, Houston, TX, USA CEQUIBIEM-Department IQUIBICEN-CONICET Genitourinary Medical...
Activation of the androgen receptor (AR) is a key step in development prostate cancer (PCa). Several mechanisms have been identified AR activation, among them signal transducer and activator transcription 3 (STAT3) signaling. Disruption STAT3 activity has associated to progression. Recent studies suggest that heme oxygenase 1 (HO-1) may play role PCa be independent its catalytic function. We sought explore whether HO-1 operates on transcriptional through axis. Our results display induction...
Estrogen receptor α (ERα) is expressed in tissues as diverse brains and mammary glands. In breast cancer, ERα a key regulator of tumor progression. Therefore, understanding what activates critical for cancer treatment particular cell biology general. Using biochemical approaches superresolution microscopy, we show that estrogen drives membrane into endosomes cells its fate determined by the presence fibronectin (FN) extracellular matrix; it trafficked to lysosomes absence FN avoids lysosomal...
Argentina stands as the seventh-largest wine producer. Its broad geographical and climatic diversity contributes to production of wines with distinctive regional characteristics. Microorganisms associated vines play a crucial role in quality. Recent studies have revealed significant differences microbial communities between grape varieties vineyard locations. In this work, we conducted comprehensive examination prokaryotic microorganisms rhizosphere vineyards located three regions Argentina....
ErbB2 is a member of the ErbB family tyrosine kinase receptors that plays major role in breast cancer progression. Located at plasma membrane, forms large clusters spite presence growth factors. Beta1 integrin, membrane receptor extracellular matrix proteins, regulates adhesion, migration and invasiveness cells. Physical interaction between beta1 integrin has been suggested although published data are contradictory. The aim present work was to study different scenarios expression activation....
The maintenance of the secretory response requires a continuous replenishment releasable vesicles. It was proposed that immediately pool (IRP) is important in chromaffin cell secretion during action potentials applied at basal physiological frequencies, because proximity IRP vesicles to voltage-dependent Ca2+ channels. However, previous reports showed after depletion too slow manage such situation. In this work, we used patch-clamp measurements membrane capacitance, confocal imaging F-actin...
The ErbB2 receptor tyrosine kinase plays a key role in mammary gland development. It forms large clusters which serve as signaling platforms for integration of extracellular information. discoidin domain (DDR) family are collagen kinases which, together with ErbB2, involved many physiological and pathological processes. Here, we investigated the interaction DDR1 receptors breast cancer cells. In contrast to beta1‐integrin, colocalizes membrane regardless their expression levels. We...
Rhizobia are Gram-negative bacteria known for their ability to fix atmospheric N2 in symbiosis with leguminous plants. Current evidence shows that rhizobia carry most cases a variable number of plasmids, containing genes necessary or free-living, common feature being the presence several plasmid replicons within same strain. For many years, we have been studying mobilization properties pSmeLPU88b from strain Sinorhizobium meliloti LPU88, an isolate Argentina. To advance characterization...
Abstract Prostate cancer (PCa) is the second leading cause of cancer-associated death in men. Prostatic tumor cell plasticity involves cooperative changes interactions between tumoral cells. The stable E-cadherin-based Adherence Junctions (AJs) play a pivotal role integrity epithelium and maintenance tissue homeostasis. Heme oxygenase-1 (HO-1) acts as rheostat counteracting oxidative inflammatory damage. Given that inflammation critical for development progression PCa, we sought to determine...