- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Ovarian function and disorders
- Urologic and reproductive health conditions
- Urinary Bladder and Prostate Research
- Genital Health and Disease
- Sexual Differentiation and Disorders
- Reproductive Health and Technologies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Testicular diseases and treatments
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Growth Hormone and Insulin-like Growth Factors
- Hypothalamic control of reproductive hormones
- Reproductive tract infections research
- Inflammatory Biomarkers in Disease Prognosis
- Stress Responses and Cortisol
- Gastrointestinal motility and disorders
- Male Reproductive Health Studies
- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Pharmacology and Obesity Treatment
- Reproductive System and Pregnancy
University of Catania
2013-2024
Ospedale Cannizzaro
2020
Pediatrics and Genetics
2016
Medica (Italy)
2013
Policlinico Universitario di Catania
2010-2013
Ospedale Garibaldi
1979-2008
College of the Atlantic
1960
Exposure to metals/metalloids, including essential and nonessential elements, has been associated male reproductive health in animals. However, findings from human studies are inconsistent. To investigate the impact of exposure multiple metals/metalloids at environmental levels on conventional semen-quality parameters. Men living rural or industrial areas were recruited by personalized letters. No exclusion criteria applied. Each man provided one semen sample blood sample. We analyzed both...
We have recently shown that patients with prostato-vesiculo-epididymitis (PVE) a greater reactive oxygen species (ROS) overproduction than prostatitis or prostato-vesiculitis. Since this biochemical stress persists even after treatment antimicrobials, it may relate to an imbalance between pro- and anti-oxidant factors at the epididymal level.To evaluate effects of antioxidant PVE, whether in presence absence pro-oxidant factors, abacterial PVE infertile normal (<1x10(6)/ml, group A, n = 34)...
The effects of long-term (14-120 months) hCG-treatment 17 male patients affected by isolated hypogonadotrophic hypogonadism (IHH) on testicular volume, plasma testosterone levels, and sperm concentration were assessed. Mean volume increased from 3.8 +/- 0.2 (Mean SEM) ml to a maximal 14.9 1.1 after 22.2 2.3 months hCG treatment. Maximal correlated positively with the recorded before had undergone any previous Testicular growth was also analysed sorting into two sub-groups according whether...
Although with some discrepancy, obese men have been reported to the worst conventional sperm parameters, but little is known about effects of body weight on mitochondrial function, chromatin condensation and apoptosis. This study was undertaken evaluate nonconventional parameters in nonsmoking overweight or without any other cause alter parameters. Fifty overweight, 50 obese, normal-weight healthy were carefully selected. Each man underwent up 2 analyses evaluation membrane potential (MMP),...
The aim of this study was to evaluate conventional semen parameters (density, morphology, and progressive motility) the flow-cytometric DNA fragmentation, mitochondrial membrane potential, phosphatidylserine externalization, chromatin compactness in patients with varicocele before after varicocelectomy. Thirty men (26.5 ± 3.2 years old, range 20-32 years) oligoasthenoteratozoospermia grade 3 left were selected (without other causes male infertility). Each them underwent sperm analysis flow...
The multifactorial pathological condition, that is, severe low sperm motility is a frequent cause of infertility. However, mechanisms underlying the development this condition are not completely understood. Single abnormalities have been reported in patients with asthenozoospermia. In study, we characterized, 22 normozoospermic men and 37 asthenozoospermia, biochemical, molecular genomic frequently occur We evaluated panel biomarkers may affect fertilizing ability Since reactive oxygen...
The aim of this study was to determine whether differences occur in seminal concentrations white blood corpuscles (sWBC) and WBC production reactive oxygen species (ROS) is related the infiltration one or more male sexual glands. We studied 70 infertile patients affected by bacterial accessory gland infections (MAGI) who were divided clinically and, ultrasound (US), into four well-characterized, aged-matched groups. Three groups presented an abnormal US scan (MAGI US+ groups): group P with...
To evaluate whether bacteriological cure, sperm outcome, spontaneous pregnancy rate and white blood cell (WBC)-related reactive oxygen species (ROS) production were related to the extent of infection an intermittent repetitive antimicrobial treatment, 122 patients with bacterial [>105 colony-forming units (CFU)/ml] male accessory gland infections (MAGI) studied. According ultrasound criteria, had prostatitis (PR, n = 52), prostatovesiculitis (PV, 32) or prostatovesiculoepididymitis (PVE,...
Chlamydia trachomatis is responsible for a widespread sexually transmitted infection. In men, it associated with wide clinical spectrum causing infertility. Furthermore, C. serovar E infection decreases motility and increases the number of non-viable sperm. No other effects have been reported on sperm despite crucial role DNA integrity function. The aim this study was to investigate apoptosis.Sperm from eight normozoospermic men were incubated increasing concentrations elementary bodies (EB)...