A5045278711- Seaweed-derived Bioactive Compounds
- Leech Biology and Applications
- Marine and coastal plant biology
- Marine Sponges and Natural Products
- Medicinal Plants and Neuroprotection
- Plant Growth Enhancement Techniques
- Venomous Animal Envenomation and Studies
- Identification and Quantification in Food
- Healthcare and Venom Research
- Marine Biology and Ecology Research
- Parasite Biology and Host Interactions
- Essential Oils and Antimicrobial Activity
- Metabolomics and Mass Spectrometry Studies
- Phytochemicals and Medicinal Plants
- Phytochemistry and Biological Activities
- Biological Activity of Diterpenoids and Biflavonoids
- Bioactive natural compounds
- Algal biology and biofuel production
- Marine and Coastal Ecosystems
- Food Science and Nutritional Studies
- Phytoestrogen effects and research
- Cephalopods and Marine Biology
- Allelopathy and phytotoxic interactions
- Nanomaterials and Printing Technologies
- Computational Drug Discovery Methods
UCSI University
2023-2024
Nilai University
2024
Xiamen University Malaysia
2020-2023
Sunway University
2020-2021
Universiti of Malaysia Sabah
2013-2018
Abstract Wearing face masks is an effective non‐pharmaceutical strategy to inhibit the transmission of airborne diseases. Nonetheless, most commercial lack disinfecting capabilities, posing risks secondary transmission, while those with antimicrobial coatings are incapable instant pathogen inactivation. Herein, a proof‐of‐concept mask demonstrated consisting Cu(OH) 2 ‐nanowire electroporation filter powered by respiration‐driven triboelectric nanogenerator (R‐TENG). The R‐TENG comprises...
In Southeast Asian nations, cultured hybrid groupers are facing serious infestation by the marine parasitic leech Zeylanicobdella arugamensis (Annelida, Hirudinea). They attach to sucking and biting on surface of skin, paving way for secondary infection upon fish. The objective study is utilize locally available seaweed control leeches. methanol extracts brown alga Sargassum polycystum C. Agardh, 1824 (Phaeophyceae) from Sabah were prepared investigated antiparasitic efficacy against Z....
Natural products serve as a valuable source of antioxidants with potential health benefits for various conditions. Lygodium microphyllum (Cav.) R. Br., also known Old World climbing fern, is an invasive fern native to Southeast Asia, Africa, South America, Australia, and Melanesia. It has been reported possess interesting pharmacological properties including hepatoprotective anti-inflammatory mechanisms. This study analyzed the bioactive metabolites that contribute antioxidant antimicrobial...
Gracilaria changii seaweed is primarily important as a source of agar with wide applications in food industries. The high demand led to gradual depletion G. natural resources. Establishment vitro culture has an role and allowing explants grow optimally under controlled conditions provide constant, continuous sufficient seedlings supply for farming. This study focused on micropropagation which different exogenous factors influencing growth were investigated: strength chosen medium Provasoli's...
Environmental pH is one of the factors contributing to abiotic stress which in turn influences growth and development macroalgae. This study was conducted order assess physiological changes Kappaphycus alvarezii under different conditions: pHs 6, ∼8.4 (control) 9. K. explants exhibited a difference daily rate (DGR) among treatments (p ≤ 0.05). The highest DGR observed control culture with followed by alkaline (pH 9) acidic 6) induced cultures. Protein expression profile generated from...
Zeylanicobdella arugamensis (Hirudinea), a marine parasitic leech, not only resulted in the mortality of host fish (Groupers) but also caused economic losses. The current study aimed to elucidate antiparasitic efficacy aqueous extract Azadirachta indica leaves against Z. and profile composition via LC-Q Exactive HF Orbitrap mass spectrometry. Different concentrations (25, 50 100 mg/mL) A. were prepared tested on leeches. total leeches was noticed with an exposure extract. average times...
Abstract Marine leech Zeylanicobdella arugamensis (Piscicolidae), an economically important parasite is infesting predominantly cultured groupers, hybrid groupers and other fish in Southeast Asian countries. In this study, we tested the anti-parasitic potential of a medicinal plant Nephrolepis biserrata found Sabah, East Malaysia against Z. . Various concentrations methanol extracts were experimentally disinfestation from its primary host groupers. The composition extract N. was determined...
The pantropical
This study examined the diversity and responses of intestinal microbiota in hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) fed diets with varying levels fishmeal replaced by black soldier fly larvae (BSFL). The 10% BSFL substitution (BSFL10) group showed highest trypsin amylase. Substituting 30% 50% weakened wall, resulting vacuoles, sparse striatal boundaries, fewer villi. Microbiota diversity, measured through Shannon’s index, was higher BSFL10 BSFL50 groups than control....
In high-throughput metabolomic profiling, chromatographic separation is crucial because a well-performed may reduce signal suppression from complex biological matrices and improve the discoverability of low-abundance metabolites. We compared performance pentafluorophenyl (PFP)- octadecylsilane (ODS)-based columns in profiling fluids. Peak resolutions consistencies were acquired using several reversed-phase evaluated. Total extracted ion chromatograms demonstrated that PFP column achieved...
Marine aquaculture development is recently impeded by parasitic leech Zeylanicobdellaarugamensis (Hirudinea, Piscicolidae) in Sabah, Malaysia. The infests a variety of cultured fishes facilities. In this study, we evaluated the antiparasitic activity chromatographic fractions medicinal plant Nephrolepis biserrata methanol extract against Z.arugamensis and highlighted potential metabolites responsible for properties through liquid chromatography (LC)–quadrupole time-of-flight (QTOF)–mass...
Vibriosis and parasitic leech infestations cause the death of various farmed fish, such as groupers, hybrid sea bass, etc., in Malaysia other Southeast Asian countries. In absence natural control agents, aquaculture operators rely on toxic chemicals to Vibrio infections leeches, which can have a negative impact environment health. present study, we investigated antivibrio antiparasitic activities aqueous extract giant sword fern (GSF) (Nephrolepis biserrata, Nephrolepidaceae, locally known...
Soft coral, Sinularia sp. had been proven to inherit promising anti-cancer properties against variety of cancer. Current study, extract was introduced Hepatocellular carcinoma (Hep 3B). Cell viability assay indicated the exhibit a dose and time dependent cytotoxicity. LC50 exhibited lowest at 72 h post treatment estimated as 45.3 µg/mL. Morphological alterations including nuclear condensation, cytoplasm shrinkage deformed cellular shape in treated Hep 3B were observable. Chemometric analysis...
Aquaculture plays a vital role in the Malaysian economy and food production however, sometimes development is impeded by parasites. The parasitic leech Zeylanicobdella arugamensis (Hirudinea) infest sea bass, snappers groupers. They feed on blood cause secondary infection which could host death short time. In this study, leaves of neem plant (Azadirachta indica) (Meliaceae) have been selected as natural product for elimination leeches Z. to evaluate phytochemical composition via ultra-high...
Invertebrates are a major reservoir for numerous cytotoxic compounds that used to defence themselves against prey and adaptation towards the environment. Throughout years, studies discovered from sponge extracts were effective wide range of cancer cells. In this study, 23 sponges comprising some 19 species collected Northeast Borneo. Sponges treated extracted using modified Folch extraction method, followed by cytotoxicity assay determine their effectiveness different colorectal From...