Although several studies have described effects of dexmedetomidine on peripheral nerve blocks, to date there is limited knowledge available the impact adjunct levobupivacaine in axillary brachial plexus block.In this study, we aimed investigate adding for an block.A total 64 patients American Society Anesthesiologists physical status I/II scheduled undergo forearm and hand surgery, which block was used, were enrolled. The randomly divided into 2 groups: group L (n = 32), performed with 39 mL...

Dexmedetomidine, because it has both sedative and analgesic properties, may be suitable for conscious sedation during painful procedures. Extracorporeal shockwave lithotripsy (ESWL) is a minimal to mildly procedure that requires sedation. We thus evaluated the utility of dexmedetomidine compared with propofol an ESWL procedure.Forty-six patients were randomly allocated into two groups receive either or elective ESWL. Dexmedetomidine was infused at 6 microg x kg(-1) h(-1) 10 min followed by...

Although the phenomenon of opioid tolerance has been widely investigated, neither nor nonopioid mechanisms are completely understood. The aim present study was to investigate role nitric oxide (NO)–cyclic guanosine monophosphate (cGMP) pathway in development morphine-induced analgesia tolerance. carried out on male Wistar albino rats (weighing 180–210 g; n = 126). To develop morphine tolerance, animals were given (50 mg/kg; s.c.) once daily for 3 days. After last dose injected day 4,...

ALTHOUGH the diagnosis of atrioventricular nodal reentrant tachycardia is made on basis electrophysiologic criteria, symptoms and results physical examination in patients with this arrhythmia may differ from those other forms supraventricular tachycardia.1 2 3 4 The present study suggests that among tachycardia, only feel pounding neck during arrhythmia. They also have higher right atrial pressures more pronounced reversal flow superior inferior vena cava systole than tachycardia. feeling...

<b><i>Objective:</i></b> To investigate the effect of thoracic paravertebral block (PVB) on pain control and morphine consumption in percutaneous nephrolithotomy operations. <b><i>Subjects Methods:</i></b> This randomized controlled clinical study was performed 60 American Society Anesthesiologists (ASA) I-II patients between ages 18 years who underwent with approval ethical committee written consent patients. Patients were randomly allocated...

Septal accessory atrioventricular (AV) pathways may be located in close vicinity of the His bundle-AV nodal conduction system. Attempts at surgical or electrical interruption these therefore result impairment normal AV conduction. This study focuses on a subset septal with an atrial insertion inside triangle Koch. In this study, they were called "midseptal."Six patients midseptal pathway (mean +/- SD age, 40 12 years; five Wolff-Parkinson-White syndrome and one concealed pathway) underwent...

We designed a randomized, double-blinded study to determine the efficacy and safety of 0.5 mg/kg intravenous ephedrine for prevention hypotension during spinal anesthesia cesarean delivery. Patients were randomly allocated into two groups: group (n=21) control (n=21). Intravenous preload 15 mL/kg lactated Ringer's solution was given. Shortly after injection, or saline injected 60 sec. The mean highest lowest heart rate in higher than those (P<0.05). There significant lower incidences nausea...

Several studies have demonstrated that serotonergic and noradrenergic systems important roles in morphine analgesia tolerance. However, the exact mechanism underlying development of tolerance is not fully understood. The aim this study was to investigate possible role serotonin/norepinephrine reuptake inhibitors (amitriptyline, venlafaxine) serotonin receptor (5-HT(1A) 5-HT(1B/1D)) agonist (dihydroergotamine) rats. To constitute tolerance, animals received (50 mg/kg; s.c.) once daily for 3...

Alpha 2 (α(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of tolerance. The purpose this study was investigate effects dexmedetomidine and guanfacine (α(2)-adrenoceptor agonists) on morphine tolerance in rats.Adult male Wistar albino rats weighing 195-205 g were used. To constitute tolerance, animals received (50 mg/kg) once daily 3 days. After last dose had been injected day 4, evaluated by tests....

Cannabinoid CB1 and CB2 receptor antagonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of tolerance. The aim this study was investigate effects AM251 (a selective antagonist) JTE907 on morphine tolerance in rats. Adult male Wistar albino rats weighing 205-225 g were used these experiments. To constitute tolerance, we a 3 day cumulative dosing regimen. After last dose injected 4, evaluated by tests. analgesic (5 mg/kg), ACEA...

Abstract The 12‐lead surface electrocardiogram is a simple and useful tool for the differential diagnosis of regular wide QRS complex tachycardia. However, criteria do not as yet exist to discriminate between ventricular tachycardia supraventricular with anterograde conduction over an accessory pathway (preexcited tachycardia). Therefore, we designed new stepwise approach three electrocardiographic preexcited prospectively studied 267 tachycardias electrophysiologically proven mechanism (≥...

Ghrelin, a peptide hormone released from the gastric endocrine glands, shows analgesic activity apart its various physiological effects. Nevertheless, effects of ghrelin receptor (GHS-R) agonists on morphine analgesia and tolerance have not yet been elucidated. The purpose this study was to evaluate agonist hexarelin antagonist [d-Lys3]-GHRP-6 antinociception in rats. A total 104 Wistar albino male adult rats (weighing approximately 220-240 g) were used experiments. To induce tolerance,...

Radiofrequency (RFJ ablation of the His bundle was attempted in 30 consecutive patients with atrial flutter or fibrillation. A 7 French quadripolar catheter a 4-mm distal electrode advanced from right femoral vein (21 patients), subclavian (two patients) and positioned across tricuspid valve. Adequate His-bundle potentials were obtained all patients. However, six atrioventricular (AV) block could not be after multiple (mean = 8) applications RF energy conventional right-sided approach. In...

Objective: To present special clinical and laboratory features of 45 cases (44 adult cases) who were intoxicated through oral route. Design: Retrospective study. Setting: Intensive care unit (ICU) a university hospital. Patients: Forty-five patients admitted to the ICU Cumhuriyet University Hospital. Results: between 4 97 years age evaluated. Intoxication was result suicide attempt in 67% accidental 33% cases. Unconsciousness, nausea vomiting common initial symptoms. The major findings...

Controlled hypotension is a technique that used to limit intraoperative blood loss provide the best possible surgical field during surgery.The aim of this double-blind, randomized, controlled study was compare effects desflurane combined with esmolol or dexmedetomidine on amount in field, recovery time, and tolerability adult patients undergoing tympanoplasty.Turkish aged 18 60 years, classified as American Society Anesthesiologists physical status I II, who were scheduled for tympanoplasty...

Fourteen patients (12 men, 2 women; 61 ± 9 years) with ventricular tachycardia and underlying heart disease underwent an attempt at radiofrequency energy catheter ablation. Twelve had coronary two dilated cardiomyopathy. Two clinical tachycardias, the ejection fraction was 38%± 11%. All tachycardias were inducible hemodynamically well tolerated (cycle length = 357 56 msec). Ablation initially successful in nine (no after ablation before discharge). recurrences (in‐hospital 4 months) one...

GURSOY, S., et al .: Radiofrequency Ablation of Symptomatic but Benign Ventricular Arrhythmias. Two cases are presented where ablation severely symptomatic ventricular arrhythmias not responding to medical therapy was accomplished with radiofrequency current application. After a routine programmed stimulation protocol, quadripolar catheter 4‐mm tip advanced percutaneously into the left ventricle in one case and right second case; after precise pace mapping, arrhythmogenic focus successfully...