A5015962886- Frailty in Older Adults
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Intensive Care Unit Cognitive Disorders
- Dementia and Cognitive Impairment Research
- Nutritional Studies and Diet
- Antioxidant Activity and Oxidative Stress
- Geriatric Care and Nursing Homes
- Body Composition Measurement Techniques
- Blood Pressure and Hypertension Studies
- Bone health and osteoporosis research
- Alzheimer's disease research and treatments
- Chronic Disease Management Strategies
- Diet and metabolism studies
- Vitamin D Research Studies
- Aging and Gerontology Research
- Anesthesia and Sedative Agents
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Pharmaceutical studies and practices
- Vitamin C and Antioxidants Research
- Gut microbiota and health
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
Istituto Nazionale di Riposo e Cura per Anziani
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Marche Polytechnic University
2024-2025
Australian Institute for Musculoskeletal Science
2024
Western Health
2024
The University of Melbourne
2024
Istituti Clinici Scientifici Maugeri
2023
University of Palermo
2022
CHR Verviers
2021
Advisory Board Company (United States)
2021
in 2010, the European Working Group on Sarcopenia Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances identifying and caring for people with sarcopenia. In early 2018, met again (EWGSOP2) update original order reflect scientific clinical evidence has built over last decade. This paper presents our updated findings. increase consistency of research design, diagnoses ultimately, care is muscle disease (muscle failure) rooted adverse changes accrue across...
Aims: Persons with high intake of polyunsaturated fatty acids (PUFAs) have lower cardiovascular morbidity and mortality. The protective effect PUFAs is mediated by multiple mechanisms, including their antiinflammatory properties. association physiological PUFA levels pro- markers has not been established. Methods Results: In 1123 persons (aged 20–98 yr), we examined the relationship between relative concentration in fasting plasma level inflammatory markers. Adjusting for age, sex, major...
Abstract Background All proposed definitions of sarcopenia include the measurement muscle mass, but techniques and threshold values used vary. Indeed, literature does not establish consensus on best technique for measuring lean body mass. Thus, objective is hampered by limitations intrinsic to assessment tools. The aim this study was review methods assess mass reach development a reference standard. Methods Literature reviews were performed members European Society Clinical Economic Aspects...
Aims The role of uric acid (UA) in the process atherosclerosis and atherotrombosis is controversial. Epidemiological studies have recently shown that UA may be a risk factor for cardiovascular diseases negative prognostic marker mortality subjects with pre-existing heart failure. Methods results We evaluate relationship between levels several inflammatory markers 957 subjects, free severe renal failure, from representative Italian cohort persons aged 65–95. Plasma white blood cell (WBC)...
Although recent epidemiological studies found a positive correlation between dietary vitamin C intake and bone mineral density, data on plasma levels of or other antioxidants in osteoporotic subjects are scanty. The aim this study was to evaluate whether antioxidant defenses decreased elderly women and, if is the case, understand osteoporosis condition characterized by increased oxidative stress. To answer these questions, vitamins C, E, A; uric acid; enzymatic activities superoxide...
Background: To our knowledge, no prospective study has examined the association between vitamin D and cognitive decline or dementia. Methods: We determined whether low levels of serum 25-hydroxyvitamin (25[OH]D) were associated with an increased risk substantial in InCHIANTI population-based conducted Italy 1998 2006 follow-up assessments every 3 years.A total 858 adults 65 years older completed interviews, assessments, medical examinations provided blood samples.Cognitive was assessed using...
Polyunsaturated fatty acids (PUFA) have a role in many physiological processes, including energy production, modulation of inflammation, and maintenance cell membrane integrity. High plasma PUFA concentrations been shown to beneficial effects on cardiovascular disease mortality. To identify genetic contributors concentrations, we conducted genome-wide association study levels six omega-3 omega-6 1,075 participants the InCHIANTI aging. The strongest evidence for was observed region chromosome...
Abstract Purpose STOPP/START is a physiological systems-based explicit set of criteria that attempts to define the clinically important prescribing problems relating potentially inappropriate medications (PIMs–STOPP criteria) and potential omissions (PPOs–START criteria). The previous two versions were published in 2008 2015. present study describes revised updated third version criteria. Methods A detailed system-by-system review literature from April 2014 March 2022 was undertaken with aim...
OBJECTIVES: To test the effectiveness of a five-item version Geriatric Depression Scale (GDS) for screening depression in community-dwelling older subjects, hospitalized patients, and nursing home residents. DESIGN: A cross-sectional study. SETTING: geriatric acute care ward, outpatient clinic, home. PARTICIPANTS: One hundred eighty-one cognitively intact subjects. MEASUREMENT: All participants had comprehensive assessment including neuropsychological evaluation by geriatrician experienced...
Vitamin D status has been hypothesized to play a role in musculoskeletal function. Using data from the InCHIANTI study, we examined association between vitamin and physical performance.A representative sample of 976 persons aged 65 years or older at study baseline were included. Physical performance was assessed using short battery (SPPB) handgrip strength. Multiple linear regression used examine (serum 25OHD), parathyroid hormone (PTH), adjusting for sociodemographic variables, behavioral...
<h3>Background</h3> Much clinical research of relevance to elderly patients examines individuals who are younger than those have the disease in question. A good example is heart failure. Therefore, we investigated extent exclusion older ongoing trials regarding <h3>Methods</h3> In context Increasing PaRticipation ElDerly Clinical Trials (PREDICT) study, data from failure were extracted World Health Organization Registry Platform on December 1, 2008. Main outcome measures proportion excluding...