A5019169413- Body Contouring and Surgery
- Preterm Birth and Chorioamnionitis
- Reproductive System and Pregnancy
- Ovarian function and disorders
- Textile materials and evaluations
- Assisted Reproductive Technology and Twin Pregnancy
- Neonatal Respiratory Health Research
- Reproductive Biology and Fertility
- Reproductive Physiology in Livestock
- Bariatric Surgery and Outcomes
- Hemostasis and retained surgical items
- Diabetes Treatment and Management
- Ectopic Pregnancy Diagnosis and Management
- Digital Imaging in Medicine
- Reproductive tract infections research
- Tendon Structure and Treatment
- Thermoregulation and physiological responses
- Reproductive Health and Contraception
- Adipokines, Inflammation, and Metabolic Diseases
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Reproductive Health and Technologies
- Microbial metabolism and enzyme function
- Surgical Sutures and Adhesives
- Historical Studies on Reproduction, Gender, Health, and Societal Changes
Royal Devon & Exeter NHS Foundation Trust
2009-2019
National Health Service
2014
St Michael’s Hospital
1996-1999
St Michaels Hospital
1996-1999
St Michael's Hospital
1996-1999
University of Bristol
1996-1998
Bristol Royal Infirmary
1997
Adipose tissue (AT) expansion in obesity is characterized by cellular growth and continuous extracellular matrix (ECM) remodeling with increased fibrillar collagen deposition. It hypothesized that the can inhibit lipid storage. Therefore, it important to fully characterize ECM's biomechanical properties its interactions cells. In this study, we compare mechanical of human subcutaneous omental tissues, which have different physiological functions. AT was obtained from 44 subjects undergoing...
Fibrosis of adipose tissue (AT) increases AT rigidity, reduces its expandability, and contributes to metabolic dysfunction. Collagen type VI, α3 (COL6A3) encodes 1 subunit a fibrotic extracellular matrix protein highly expressed in rodent AT. Knockout collagen VI led significant improvement health obese, diabetic ob/ob mice. However, it is unknown whether this has the same significance human We therefore aimed undertake comprehensive assessment COL6A3 relation obesity. Characterization...
There is growing evidence that the pathogenic effects of bacterial vaginosis may not be confined to lower genital tract. Possible associations with infertility and on fertilization implantation were studied in patients undergoing in-vitro (IVF) treatment. High vaginal swabs taken at time oocyte collection assessed by Gram staining. The prevalence intermediate normal flora 301 was 25.6, 14.0 60.4% respectively. Bacterial more prevalent tubal (31.5%, n = 149) compared non-tubal (19.7%, 152)...
We questioned the policy of routine microbiological culture semen prior to in-vitro fertilization (IVF) with a view prescribing antibiotics reduce risk introducing seminal infection into embryo system. An initial retrospective study examined serum microbiology reports 449 couples undergoing IVF or gamete intra-Fallopian transfer (GIFT). In samples taking >/=1 days reach laboratory compared same-day delivery there was increased frequency significant enterococci (27 versus 15%, P < 0.01). >/=2...
Abstract The effect of maternal age on the outcome threatened miscarriage after ultrasound has confirmed fetal heart (FH) pulsation was assessed. At a university teaching hospital, 138 women presenting with bleeding before 12 weeks’ gestation were followed up until delivery or pregnancy loss. Those multiple ectopic pregnancy, social termination assisted conception and temporary residence excluded. Outcome measures loss, abnormalities, preterm delivery, low birthweight cesarean delivery. Age...
Subjects with type-2 diabetes are typically obese dysfunctional adipose tissue (AT). Glucagon-like peptide-1 (GLP-1) analogues routinely used to improve glycaemia. Although, they also aid weight loss that improves AT function, their direct effect on function is unclear. To explore GLP-1 analogues' influence human AT's cytokine and extracellular matrix (ECM) regulation, we therefore obtained treated omental (OMAT) subcutaneous (SCAT) samples Exendin-4, an agonist of the receptor (GLP-1R).OMAT...