A5082851164- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Plant Virus Research Studies
- RNA modifications and cancer
- Plant Disease Resistance and Genetics
- Plant Molecular Biology Research
- interferon and immune responses
- Plant nutrient uptake and metabolism
- Plant and Fungal Interactions Research
- Nicotinic Acetylcholine Receptors Study
- RNA Research and Splicing
- Bacteriophages and microbial interactions
- Biopolymer Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- RNA and protein synthesis mechanisms
- Genomics and Phylogenetic Studies
- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Insect-Plant Interactions and Control
- RNA regulation and disease
Tsinghua University
2018-2024
Center for Life Sciences
2019-2021
Peking University
2018-2021
Tongji Hospital
2017-2018
Huazhong University of Science and Technology
2017-2018
In plants, RNA-directed DNA methylation (RdDM)-mediated transcriptional gene silencing (TGS) is a natural antiviral defense against geminiviruses. Several geminiviral proteins have been shown to target the enzymes related methyl cycle or histone modification; however, it remains largely unknown whether and by which mechanism geminiviruses directly inhibit RdDM-mediated TGS. this study, we showed that Cotton leaf curl Multan virus (CLCuMuV) V2 interacts with Nicotiana benthamiana AGO4...
RNA polymerases IV and V (Pol Pol V) are required for the generation of noncoding RNAs in RNA-directed DNA methylation (RdDM). Their subunit compositions resemble that II. The mechanism accessory factors involved their assembly remain largely unknown. In this study, we identified mutant alleles MINIYO (IYO), QUATRE-QUART2 (QQT2), NUCLEAR POLYMERASE B11/D11/E11 (NRPB/D/E11) cause defects RdDM Arabidopsis thaliana. We found IV-dependent small interfering V-dependent transcripts were greatly...