A5103009903- Histiocytic Disorders and Treatments
- Infectious Disease Case Reports and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical research and treatments
- Nail Diseases and Treatments
- Vascular Tumors and Angiosarcomas
- Cutaneous Melanoma Detection and Management
- Optical Coherence Tomography Applications
- Chemotherapy-related skin toxicity
- Respiratory Support and Mechanisms
- Neurological and metabolic disorders
- Acute Myeloid Leukemia Research
- Occupational Health and Burnout
- Healthcare Quality and Management
- Chronic Myeloid Leukemia Treatments
- Public Health in Brazil
- Neurological disorders and treatments
- Healthcare during COVID-19 Pandemic
- Genetic Neurodegenerative Diseases
- Moyamoya disease diagnosis and treatment
- Healthcare professionals’ stress and burnout
- Multiple Myeloma Research and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Cutaneous lymphoproliferative disorders research
- Health and Lifestyle Studies
Hospital Garcia de Orta
2018-2024
Hospital Pedro Hispano
2012-2019
Instituto Português de Oncologia Francisco Gentil
2011
Abstract Acute megakaryoblastic leukemia (AMKL) with t(1;22)(p13;q13) is a subset of acute myeloid (AML) representing <1% all cases and about 70% pediatric AMKL in the first year life. We present case 7‐month‐old female whom bone marrow karyotype showed derivative chromosome der(22)t(1;22)(p13;q13). The RBM15–MKL1 fusion transcript was detected by RT‐PCR confirmed sequencing analyses. FISH analyses revealed presence four‐way translocation t(1;22;17;18)(p13;q13;q22;q12). Pediatr Blood...
Cutaneous plasmacytoma is an uncommon observation in clinical practice. It usually a consequence of direct extension from underlying bony lesion, the setting multiple myeloma. In our case, 77-year-old woman, with stage IIIA IgG lambda myeloma for two years, presented firm nodular violaceous cutaneous lesions on left arm without bone osteolytic or subcutaneous tumors; biopsy was consistent plasmacytoma. The patient had suffered spontaneous humeral fractures treated prosthesis replacement just...
To report a rate case of Juvenile xanthogranuloma in newborn infant.We present the 31-week preterm with multiple skin lesions whose clinical, histological and immunohistochemical findings allowed diagnosis juvenile xanthogranuloma. Currently, patient has nine months-old, there is no aggravation or evidence extra-cutaneous involvement, particularly ophthalmic.Juvenile rare benign condition, included vast group non-Langerhans histiocytosis. It typically occurs pediatric age may have neonatal...
Introdução: A onicomadese é o descolamento da placa ungueal a partir prega proximal unha. Esta alteração autolimitada foi descrita como uma complicação tardia doença mão-pé-boca, infeção viral comum em crianças. Descrição do caso: Criança sexo feminino de quatro anos, acompanhada pelo pai (representante legal), recorreu consulta aberta (CA) com um quadro febre alta, vesículas e pústulas na mucosa oral, língua, períneo, palmas plantas das mãos pés. Foi feito diagnóstico mão-pé-boca. Após três...
Non-puerperal uterine inversion is a rare complication, and its incidence not well documented in the current literature. The most common risk factor presence of submucosal fibroids. Nonetheless, any endometrial pathology can precipitate this may also have malignant etiology. A detailed anamnesis structured complementary diagnostic exams, along with surgical team prepared for resolution gynecological condition, are essential. This case presents 76-year-old woman non-puerperal following...
Fundamentos: As reações de hipersensibilidade durante a quimioterapia em crianças têm sido documentadas forma crescente. A dessensibilização fármacos é um procedimento desconhecido por grande parte dos oncologistas, apesar permitir que os doentes sejam tratados com agentes primeira linha, afetando o prognóstico final. Atualmente, ainda não existem normas orientação idade pediátrica e princípios gerais adotados para adultos aplicados crianças. Objetivo: Descrever experiência serviço...
A sindrome de encefalopatia posterior reversivel e caracterizada por cefaleias, alteracao do estado consciencia, convulsoes, manifestacoes visuais, alteracoes imagiologicas generalizadas predominio posterior, reversiveis, semelhantes em todos os casos, independentemente da causa primaria. Hoje sabe-se que nem sempre atinge apenas a substância branca, nao se limita ao envolvimento circulacao cerebral reversivel. Apresentam-se casos dois jovens, previamente saudaveis, com as clinicas desta...
Introdução: A tosse é um dos sintomas mais comuns em idade pediátrica. O recurso a fármacos frequente, apesar da sua eficácia e segurança não estarem comprovadas. objetivo deste estudo foi compreender perspetiva que os cuidadores têm descrever as medidas terapêuticas utilizadas.
Background: Trastuzumab is a widely used and well-tolerated drug. Pulmonary toxicity has been described; however, the low incidence, variability at presentation, nonspecific characteristics often make it an exclusion diagnosis. Case presentation: We present case of 62-year-old women admitted to our service with fever shortness breast after treatment trastuzumab. From study performed, no other cause was found explain event patient kept worsening until diagnosis established. Conclusion:...
ABSTRACT Introduction Burnout Syndrome is not classified as a disease or medical condition, but an occupational phenomenon, characterized by emotional exhaustion, depersonalization and decreased sense of professional fulfillment. It increasingly frequent health problem among doctors, having become factor great wear tear, especially after the enormous impact Covid-19 pandemic on these professionals. Objectives/Methodology This review aims to identify contributory factors, characteristics...