Dorothea Helmer

ORCID: 0000-0003-0295-9701
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About
Contact & Profiles
Research Areas
  • Additive Manufacturing and 3D Printing Technologies
  • Microfluidic and Capillary Electrophoresis Applications
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Electrowetting and Microfluidic Technologies
  • 3D Printing in Biomedical Research
  • Surface Modification and Superhydrophobicity
  • Nanofabrication and Lithography Techniques
  • Advanced Sensor and Energy Harvesting Materials
  • Photopolymerization techniques and applications
  • Photonic Crystals and Applications
  • Modular Robots and Swarm Intelligence
  • Monoclonal and Polyclonal Antibodies Research
  • Biosensors and Analytical Detection
  • Nonlinear Optical Materials Studies
  • Chemical Synthesis and Analysis
  • Chemokine receptors and signaling
  • Adhesion, Friction, and Surface Interactions
  • Advanced biosensing and bioanalysis techniques
  • Microfluidic and Bio-sensing Technologies
  • Advanced Biosensing Techniques and Applications
  • Advanced Materials and Mechanics
  • Laser Material Processing Techniques
  • Pigment Synthesis and Properties
  • Computer Graphics and Visualization Techniques
  • Photochromic and Fluorescence Chemistry

Glassomer (Germany)
2020-2025

University of Freiburg
2019-2025

Karlsruhe Institute of Technology
2014-2019

Technical University of Darmstadt
2015-2018

Clemenshospital Münster
2015-2018

Abstract Fused silica glass is the material of choice for many high‐performance components in optics due to its high optical transparency combined with thermal, chemical, and mechanical stability. Especially, generation fused microstructures interest microoptical biomedical applications. Direct laser writing (DLW) a suitable technique generating such devices, as it enables nearly arbitrary structuring down sub‐micrometer level. In this work, true 3D transparent using DLW tens micrometer...

10.1002/adma.202006341 article EN cc-by Advanced Materials 2021-01-14

Abstract Fused silica glass is the preferred material for applications which require long-term chemical and mechanical stability as well excellent optical properties. The manufacturing of complex hollow microstructures within transparent fused particular interest for, among others, miniaturization synthesis towards more versatile, configurable environmentally friendly flow-through chemistry high-quality waveguides or capillaries. However, microstructuring such three-dimensional structures in...

10.1038/s41467-019-09497-z article EN cc-by Nature Communications 2019-03-29

Liquid glass is a photocurable amorphous silica nanocomposite that can be structured using soft replication molds and turned into via thermal debinding sintering. Simple polymer bonding techniques allow the fabrication of complex microsystems in like microfluidic chips. step toward prototyping microstructures at low cost without requiring cleanroom facilities or hazardous chemicals.

10.1002/adma.201506089 article EN Advanced Materials 2016-04-09

Abstract Fused silica glass is one of the most important high‐performance materials for scientific research, industry, and society. However due to its high chemical thermal resistance as well hardness, fused notoriously difficult structure. This work introduces Glassomer, a solid nanocomposite, which can be structured using polymer molding subtractive technologies at submicrometer resolution. After processing Glassomer turned into optical grade during final heat treatment. The resulting has...

10.1002/adma.201707100 article EN Advanced Materials 2018-04-02

Polymethylmethacrylate (PMMA) is one of the most important thermoplastic materials and a widely used material in microfluidics. However, PMMA usually structured using industrial scale replication processes, such as hot embossing or injection molding, not compatible with rapid prototyping. In this work, we demonstrate that microfluidic chips made from can be 3D printed fused deposition modeling (FDM). We FDM minimum channel cross-section ~300 µm variety different geometries mixer structures...

10.3390/mi11090873 article EN cc-by Micromachines 2020-09-19

Shaping silica like a polymer Glass is tremendously useful, but it energy intensive to make because of the high melting temperature and processing methods that require melts. Mader et al. circumvented need for glass using plastic nanocomposite injection molding (see Perspective by Dylla-Spears). The low-temperature can produce parts in as little 5 seconds with spatial resolution. strategy provides different potentially less energy-intensive method mass producing made glass. Science , this...

10.1126/science.abf1537 article EN Science 2021-04-09

Abstract The customized processing of polymer materials in the microscale by high‐resolution 3D printing provides an easy access to advanced applications fields optics, microfluidics, tissue engineering, and life science. However, enclosed structures scale tens microns such as closed microfluidic channels remains a challenge channel often are clogged residual cured resin. Dual‐curing systems based on off‐stoichiometric thiol‐ene thiol‐ene/epoxy chemistry well‐known for adhesive‐free bonding...

10.1002/adfm.202401516 article EN cc-by Advanced Functional Materials 2024-04-11

Fabricating microstructures on curved surfaces is of great importance in several engineering fields, and it an ongoing challenge to develop technologies that do not require complicated devices cumbersome procedures. A novel approach presented for fabricating with different topographies using flexible microstructured hydrogels as molds. The hydrogel film first via spatially controlled ultraviolet illumination utilizing its photo-responsive property. then transferred a desired surface. Due low...

10.1002/smll.202411751 article EN cc-by Small 2025-02-12

Undesired growth of biofilms represents a fundamental problem for all surfaces in long-term contact with aqueous media. Mature resist most biocide treatments and often are pathogenic threat. One way to prevent biofilm on is by using slippery liquid-infused porous (SLIPS). SLIPS consist substrate which infused lubricant immiscible the medium bacteria suspended. Because lubricant, cannot attach surface thus formation prevented. For this purpose, we manufactured substrates different porosity...

10.1021/acsami.8b12542 article EN ACS Applied Materials & Interfaces 2019-01-15

Porous membranes with special wetting properties have attracted great interest due to their various functions and wide applications, including water filtration, selective oil/water separation oil skimming. Special such as superhydrophobicity can be achieved by controlling the surface chemistry well topography of a substrate. Three-dimensional (3D) printing is promising method for fast easy generation structures. The most common 3D superhydrophobic materials two-step fabrication process:...

10.1039/d1ta03352b article EN cc-by-nc Journal of Materials Chemistry A 2021-01-01

Abstract Microstructured molds are essential for fabricating various components ranging from precision optics and microstructured surfaces to microfluidics. However, conventional fabrication technology such as photolithography requires expensive equipment a large number of processing steps. Here, we report facile method fabricate micromolds based on reusable photoresponsive hydrogel: Uniform micropatterns engraved into the hydrogel surface using photo masks under UV irradiation within few...

10.1038/s41467-024-50008-6 article EN cc-by Nature Communications 2024-07-06

Highly fluorinated perfluoropolyether (PFPE) methacrylates are of great interest for transparent and chemically resistant microfluidic chips. However, so far only a few examples material formulations three-dimensional (3D) printing these polymers have been demonstrated. In this paper we show that chips can be printed using highly by 3D stereolithography printing. We developed photocurable resin in commercial benchtop printers. demonstrate the with minimal cross-sectional area 600 µm...

10.3390/mi9030115 article EN cc-by Micromachines 2018-03-08

Abstract Superhydrophobic surfaces and surface coatings are of high interest for many applications in everyday life including non-wetting low-friction as well functional clothing. Manufacturing these is intricate since superhydrophobicity requires structuring on a nano- to microscale. This delicate makes most superhydrophobic very sensitive abrasion renders them impractical real-life applications. In this paper we present transparent fluorinated polymer foam that synthesized by simple...

10.1038/s41598-017-15287-8 article EN cc-by Scientific Reports 2017-11-02

In recent years, additive manufacturing (AM) of glass has attracted great interest in academia and industry, yet it is still mostly limited to liquid nanocomposite-based approaches for stereolithography, two-photon polymerization, or direct ink writing. Melt-extrusion-based processes, such as fused deposition modeling (FDM), which will allow facile large thin-walled components simple multimaterial printing are so far inaccessible AM transparent silica glass. Here, melt-extrusion-based...

10.1002/advs.202103180 article EN cc-by Advanced Science 2021-10-20

Pneumatic actuators are of great interest for device miniaturization, microactuators, soft robots, biomedical engineering, and complex control systems. Recently, multi-material have become high to researchers due their comprehensive range suitable applications. Three-dimensional (3D) printing pneumatic would be the ideal way fabricate customized actuators, but so far, this is mostly limited deposition-based methodologies, such as fused deposition modeling (FDM) or Polyjetting. Vat-based...

10.3390/mi14020244 article EN cc-by Micromachines 2023-01-18

Elastomeric materials, most prominently polydimethylsiloxane, are of great importance for microfluidic systems. Unfortunately, elastomeric materials used in these systems so far show poor chemical resistance. Fluorinated elastomers promising chemistry-on-chip applications performed on systems, but challenging to shape the microscale and difficult bond which is a required step fabrication embedded chips. In this work, custom-synthesized fluorinated photocurable resin can be structured using...

10.1016/j.addma.2024.103991 article EN cc-by-nc Additive manufacturing 2024-01-23

Abstract Lignin, one of the most abundant biomaterials and a large‐scale industrial waste product, is promising filler for polymers as it reduces amount fossil resources readily available. 3D printing well‐known producing detailed polymer structures in small sizes at low production. Especially light‐assisted powerful technique production high‐resolution structures. However, lignin acts very efficient absorber UV visible light limiting printability composites, reducing its potential...

10.1002/advs.202406311 article EN cc-by Advanced Science 2024-08-13

Materials matter in microfluidics. Since the introduction of soft lithography as a prototyping technique and polydimethylsiloxane (PDMS) material choice microfluidics community has settled with using this almost exclusively. However, for many applications PDMS is not an ideal given its limited solvent resistance hydrophobicity which makes it especially disadvantageous certain cell-based assays. For these polystyrene (PS) would be better choice. PS been used biology research analytics decades...

10.1039/c4lc00045e article EN cc-by Lab on a Chip 2014-01-01

Gallium-based liquid metal nonspherical droplets (plugs) have seen increasing demand recently mainly because their high aspect ratios make them beneficial for a wide range of applications, including microelectromechanical systems (MEMS), microfluidics, sensor technology, radio-frequency devices, actuators, and switches. However, reproducibility the generation such plugs, as well precise control over size, is yet challenging. In this work, simple on-chip plug generator using commercially...

10.1002/adma.202201469 article EN cc-by Advanced Materials 2022-04-15

Polymethymethacrylate (PMMA) is one of the most important thermoplasts and a commonly used material in microsystem fabrication, for example, microfluidics owning mainly to its optical transparency, biocompatibility, low autofluorescence, cost. However, being thermoplastic PMMA typically structured using industrial replication techniques making unsuitable rapid prototyping. The fact that neither nor processing technique can be directly transferred from laboratory state makes...

10.1002/adem.201700699 article EN Advanced Engineering Materials 2017-10-17

Softness plays a key role in the deformation of soft elastic substrates at three-phase contact line, and acting forces lead to formation wetting ridge due elastocapillarity. The change surface profiles different softness has great impact on droplet behavior phenomena. Commonly used materials study are swollen polymeric gels or polymer brushes. These offer no possibility demand. Therefore, adjustable surfaces with tunable highly sought-after achieve on-demand transition between states...

10.1021/acsami.2c22979 article EN cc-by-nc-nd ACS Applied Materials & Interfaces 2023-05-22
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