A5032911147- Ectopic Pregnancy Diagnosis and Management
- Gestational Trophoblastic Disease Studies
- Maternal and Perinatal Health Interventions
- Reproductive System and Pregnancy
- Pelvic floor disorders treatments
- Ovarian function and disorders
- Gynecological conditions and treatments
- Viral-associated cancers and disorders
- Homicide, Infanticide, and Child Abuse
- Reproductive Biology and Fertility
- Global Cancer Incidence and Screening
- Urinary Bladder and Prostate Research
- Antibiotics Pharmacokinetics and Efficacy
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Cervical Cancer and HPV Research
- Galectins and Cancer Biology
- Antibiotic Use and Resistance
- Maternal and fetal healthcare
- Endometrial and Cervical Cancer Treatments
- Urinary Tract Infections Management
- Antifungal resistance and susceptibility
- Burkholderia infections and melioidosis
- Pregnancy-related medical research
- Nursing Roles and Practices
Monash Health
2024-2025
Burnley General Teaching Hospital
2007-2023
East Lancashire Hospitals NHS Trust
2010-2023
University of Birmingham
2008
Royal Bolton Hospital
1999
Liverpool Women's Hospital
1995
University of Liverpool
1995
Riyadh Armed Forces Hospital
1994
The role of reduced intensity conditioning allogeneic stem transplantation (RICalloSCT) in the management patients with Hodgkin's lymphoma remains controversial.To further define its we have conducted a retrospective analysis 285 HL who underwent RICalloSCT order to identify prognostic factors that predict outcome. Eighty percent had undergone prior autologous cell and 25% refractory disease at transplant.Non-relapse mortality was associated chemorefractory disease, poor performance status,...
Tubal ectopic pregnancies can cause substantial morbidity or even death. Current treatment is with methotrexate surgery. Methotrexate fails in approximately 30% of women who subsequently require rescue Gefitinib, an epidermal growth factor receptor inhibitor, might improve the effects methotrexate. We assessed efficacy oral gefitinib methotrexate, versus alone, to treat tubal pregnancy.We performed a multicentre, randomised, double-blind, placebo-controlled trial across 50 UK hospitals....
Brucellosis is a rare zoonotic infection most commonly seen in parts of the Northern Hemisphere. Infections Australia are uncommon and occur predominantly Queensland New South Wales due to exposure Brucella suis through wild pig hunting activities. We describe clustering two cases brucellosis Victoria confirmed by genomic analysis but with no identified exposure. detail medical management, laboratory confirmation, public health investigation. While source outbreak remains unclear,...
SummaryTwo hundred primigravid women delivered vaginally were allocated at random to one of two groups. Patients in group undergo episiotomy unless it was considered unnecessary (elective). Those the other not be essential (selective). The resultant rates 83 and 53 per cent respectively. An intact perineum more common among those routine but these patients had second degree perineal lacerations (8 cent). No difference found between groups either paraurethral or lateral vaginal wall...
Abstract Background Outpatient parenteral antimicrobial therapy (OPAT) can deliver extended treatment of fungal infections in an ambulatory setting, whilst minimizing burden and cost. The dosing interval rezafungin may potentiate the benefits OPAT. Methods This retrospective cohort study includes all adult patients who received echinocandin a large OPAT programme between 2012 2022. Patient characteristics, outcomes were studied. Data analysed to determine effects replacing daily with weekly...
Key content Caesarean section rates are rising globally; while obstetric consequences well defined, long‐term gynaecological sequelae frequently overlooked. niche results from poor healing of the uterine scar and is being increasingly reported as an important factor in a variety new symptoms after caesarean section. Until recently, lack high‐quality evidence has hampered diagnostic assessment. Recent publications provide useful consensus for improved diagnosis guidance on management, with...
Abstract Study question Is a combination of parenteral methotrexate and oral gefitinib more effective than alone in the treatment tubal ectopic pregnancy? Summary answer In women with pregnancy, adding to parental does not offer clinical benefit over increases minor adverse reactions. What is known already Current pregnancies or surgery. Methotrexate fails ∼30% they require rescue At time design trial, it had been shown preclinical studies that implantation sites express high levels...
The aim of this study was to investigate the influence diagnostic throughput on survival outcome for women with cancer cervix. We conducted a case note review 359 in Lancashire and Greater Manchester diagnosed cervix during 1990, identified from records held by North Western Regional Cancer Registry. Univariate multivariate analyses were undertaken woman, disease treatment related factors. Following adjustment woman- disease-related factors there no evidence statistically significant...
Background Tubal ectopic pregnancies can cause significant morbidity or even death. Current treatment is with methotrexate surgery. However, fail in approximately 30% of women. Gefitinib, an epidermal growth factor receptor inhibitor, may improve the effects methotrexate. We assessed efficacy administering oral gefitinib methotrexate, versus alone, to treat a tubal pregnancy. Objectives To test hypothesis combination increase resolution stable pregnancy without need for surgery, compared...
<h3>Introduction</h3> Rates of Caesarean section are rising throughout the United Kingdom. Therefore increasing numbers women entering subsequent pregnancies with a uterine scar. Some these will choose to attempt another vaginal birth after (VBAC). Our trust delivers 6500 annually in two separate consultant led maternity units. The authors undertook review identify areas weak practice and facilitate accurate antenatal counselling our success rates. <h3>Methods</h3> This was retrospective...