- Pomegranate: compositions and health benefits
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Phytochemicals and Medicinal Plants
- Animal Virus Infections Studies
- Periodontal Regeneration and Treatments
- Oral Health Pathology and Treatment
- Hops Chemistry and Applications
- Cynara cardunculus studies
University of Banja Luka
2022-2023
University of East Sarajevo
2022
Primary HealthCare
2022
Primary Health Care
2022
Public Health Institute of the Republic of Srpska
2022
Pomegranate peel extract (PoPEx) has been shown to have antioxidant and anti-inflammatory properties, but its effect on the adaptive immune system not sufficiently investigated. In this study, treatment of human peripheral blood mononuclear cells (PBMC) with PoPEx (range 6.25-400 µg/mL) resulted in cytotoxicity at concentrations 100 µg/mL higher, due induction apoptosis oxidative stress, whereas autophagy was reduced. At non-cytotoxic concentrations, opposite these processes observed...
Our recent study has shown that pomegranate peel extract (PEx) showed significant immunomodulatory activity, which might be caused by ellagitannins. The aim of this work was to test the hypothesis ellagitannin components act synergistically in modulation cytokine production.Human peripheral blood mononuclear cells (PBMCs) from healthy donors were stimulated with phytohemagglutinin and treated different concentrations PEx or punicalagin (PG), punicalin (PN), ellagic acid (EA), alone their...
Pomegranate has shown a favorable effect on gingivitis/periodontitis, but the mechanisms involved are poorly understood. The aim of this study was to test pomegranate peel extract (PoPEx) gingiva-derived mesenchymal stromal cells (GMSCs) under physiological and inflammatory conditions. GMSC lines from healthy (H) periodontitis (P) gingiva (n = 3 each) were established. treated with two non-toxic concentrations PoPEX (low-10; high-40 µg/mL), or without additional lipopolysaccharide (LPS)...
During the last two and a half years, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread around world. Most of SARS-CoV-2 vaccines are designed to produce anti-SARS-CoV-2 immunoglobulin G (IgG) against viral S-glycoprotein. The aim this study was measure anti-S antibody titres among medical personnel who had been fully vaccinated with different types vaccines, compare them those were COVID-19 convalescents.In serum collected from 261 healthcare workers, whom...
Abstract Healthcare workers (HCW) in primary healthcare centres the Republic of Srpska, Bosnia and Herzegovina, are on first combat line with COVID-19. This study aimed to assess seroprevalence SARS-CoV-2 among HCW at analyse risk exposure COVID-19, clinical signs vaccination status. A cross-sectional was conducted selected between 19 March 30 April 2021. Antibodies against virus were detected by enzyme-linked immunosorbent assay (ELISA). total 1,023 (mean age 45 years; 71% female) included...