A5010808686- Surfactants and Colloidal Systems
- Lipid Membrane Structure and Behavior
- Advanced Polymer Synthesis and Characterization
- Nanoparticle-Based Drug Delivery
- Lanthanide and Transition Metal Complexes
- Plant Virus Research Studies
- Nanopore and Nanochannel Transport Studies
- Genomics and Phylogenetic Studies
- Mass Spectrometry Techniques and Applications
- Liquid Crystal Research Advancements
- Advancements in Transdermal Drug Delivery
- Bacteriophages and microbial interactions
Adam Mickiewicz University in Poznań
2021-2025
The rise of antibiotic-resistant bacteria demands new antimicrobial strategies. Glyceryl monolaurate (GML) shows antibacterial activity against Gram-positive like S. aureus but is ineffective Gram-negative E. coli due to its outer membrane. GML's limited solubility and susceptibility bacterial lipases hinder direct use. This study developed glyceryl monooleate (GMO) lipid liquid crystalline nanoparticles (LLCNPs) incorporating GML enhance stability efficacy. Using a central composite design...
Self-assembled lipid nanoparticles containing Gd-chelating lipids are considered a new generation of positive Magnetic Resonance Imaging contrast agents (MRI CAs). High molecular weight imposes reduced reorientation (τr) and corresponding...
Abstract Background Lipid liquid crystalline nanoparticles (LLCNPs) emerge as a suitable system for drug and contrast agent delivery. In this regard due to their unique properties, they offer solubility of variety active pharmaceutics with different polarities increasing stability the possibility controlled Nevertheless, most crucial aspect underlying application LLCNPs or delivery is unequivocal assessment biocompatibility, including cytotoxicity, genotoxicity, related aspects. Although...
Virus-like particles (VLPs), due to their nanoscale dimensions, presence of interior cavities, self-organization abilities and responsiveness environmental changes, are interest in the field nanotechnology. Nevertheless, comprehensive knowledge VLP self-assembly principles is incomplete. formation governed by two types interactions: protein–cargo protein–protein. These interactions can be modulated physicochemical properties surroundings. Here, we used brome mosaic virus (BMV) capsid protein...