A5012391951- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Animal health and immunology
- Reproductive Physiology in Livestock
- Microbial infections and disease research
- Microfluidic and Bio-sensing Technologies
- Liver Disease Diagnosis and Treatment
- Kruppel-like factors research
- Diet, Metabolism, and Disease
- Mesenchymal stem cell research
- Streptococcal Infections and Treatments
- Rheumatoid Arthritis Research and Therapies
- Growth Hormone and Insulin-like Growth Factors
- Inflammatory Biomarkers in Disease Prognosis
- Erythropoietin and Anemia Treatment
- Diet and metabolism studies
- Lexicography and Language Studies
- Renin-Angiotensin System Studies
- Ruminant Nutrition and Digestive Physiology
- Eosinophilic Disorders and Syndromes
- Steroid Chemistry and Biochemistry
- Iron Metabolism and Disorders
- Chronic Myeloid Leukemia Treatments
- Cytokine Signaling Pathways and Interactions
- Alcohol Consumption and Health Effects
- Effects of Environmental Stressors on Livestock
University of Belgrade
2017-2024
Lifestyle modifications are the main support of nonalcoholic fatty liver disease (NAFLD) therapy. Weight loss is one primary goals in NAFLD, but effects different calorie-restricted diets remain unclear. Thus, we evaluated two diets—the Mediterranean diet (Med diet) and low-fat diet—on status, cardiometabolic markers, acid profiles patients with NAFLD. Twenty-four overweight/moderately obese men were randomly assigned to consume these diets. Lipid levels, glucose, insulin, enzymes,...
Anemia is a common complication of cancer that has been associated with poor response to treatment and decreased survival in many malignancies. A retrospective chart review was undertaken determine the effects hemoglobin (Hb) levels, measured prior initiation chemotherapy before each cycle, clinical prognostic factors (e.g., age, tumor stage, residual size, hematologic parameters, type health insurance) 250 ovarian patients treated between 1985 1998. All were scheduled receive at least 6...
Hydroxyurea (HU) is a nonalkylating antineoplastic agent used in the treatment of hematological malignancies. HU DNA replication stress inducer, and as such, it may induce premature senescence-like cell phenotype; however, its repercussion on bystander proliferation has not been revealed so far. Our results indicate that strongly inhibited peripheral blood mesenchymal stromal cells (PBMSC) by cycle arrest S phase, that, consequently, PBMSC acquire senescence-related phenotypical changes....
This study has been performed to determine the mechanism of activation myeloid related S100A proteins by inflammatory cytokines in myeloproliferative neoplasm (MPN). Besides microarray analysis MPN‐derived CD34 + cells, we analysed pro‐inflammatory IL6 and anti‐inflammatory IL10 dependence NF‐κB, PI3K‐AKT, JAK‐STAT signalling during induction mononuclear cells MPN, immunoblotting flow cytometry. We observed reduced gene expression linked NF‐κB inflammation cells. Both S100A8 100A9 protein...
Abstract Calf bronchopneumonia is complex multifactorial disease and for its accurate diagnosis therapy, besides clinical examination, microbiologic, hematologic biochemical analyses could be necessary. In general, additional are not implemented, mainly because the biomarkers defined. To establish which analysis might useful determining severity of disease, we analyzed 23 three-month old calves with mild signs 15 age-matched healthy calves. Pasteurella multocida was isolated from deep nasal...
In several systems, hydroxyurea has been shown to trigger nitric oxide (NO) release or activation of NO synthase (NOS). To elucidate this duality in its pharmacological effects, during myelosuppression, we individually examined hydroxyurea’s (NO releasing agent) and metabolites’ (stable degradation products) effects on erythroid colony growth NOS/NO levels mice using scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO). Hydroxyurea nitrite/nitrate decreased the bone marrow...
Abstract Failure of passive transfer (FPT) immunoglobulins (IgG) is associated with increased morbidity and mortality calves. In this study we evaluated the digital Brix refractometer usefulness for assessment FPT. A number 16 colostrum samples from first milking (2-3h post-partum) Holstein-Friesian dairy heifers 29 blood sera 3-6 days old calves were analyzed a refractometer. Total proteins determined by biuret reaction. Colostral IgG radial immunodiffusion (RID), colostral whey serum γ...
The function of immune complexes in rheumatoid arthritis (RA) is related to their composition and size. Using dynamic light scattering (DLS), we investigated the link between RA circulating complex (CIC) particles' size CIC immunoglobulin level. In this study, 30 patients healthy individuals were included. IgA, IgG, IgM found all analyzed CICs, but more IgA IgG than control CICs. both DLS detected 50 particles that differed clustered around two groups: with a 7.5-164 nm radius 342-1718...
Alcohol-associated liver disease (ALD) is a common non-communicable chronic characterized by spectrum of conditions ranging from steatosis and alcohol-associated steatohepatitis (AH) to fibrosis, cirrhosis, hepatocellular carcinoma (HCC). The pathogenesis ALD involves complex interplay various molecular, biochemical, genetic, epigenetic, environmental factors. While the mechanisms are well studied, therapeutic options remain limited. Alpinetin, natural flavonoid with antioxidant...
Abstract This research paper addresses the hypothesis that an oral supplementation with organically modified clinoptilolite will improve colostrum quality in primiparous dairy cows whilst having no adverse effects on cows' health. A total of 36 pregnant Holstein cattle were randomly assigned to receive daily drenching, two hours following morning feeding, 1 l water containing either 0 g/l ( n = 16) or 150 20) clinoptilolite. Treatment lasted from 24 ± 4 d prior expected parturition until...
Redox imbalance in peripartum period influences health of dairy cows and their foetus and, through the colostrum, new-born calves. Oxidative stress cattle can be suppressed by dietary supplementation with natural minerals, we investigated effect organically modified clinoptilolite on redox status parameters healthy pregnant primiparous cows. Holstein were randomly assigned to receive daily oral drenching, 1 L water containing either 0 g/L (n = 14; control group) or 150 17; supplemented...