A5030066936- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Clinical Nutrition and Gastroenterology
- Neonatal and fetal brain pathology
- Child Nutrition and Feeding Issues
- Infant Health and Development
- Digestive system and related health
- Breastfeeding Practices and Influences
- Metabolism and Genetic Disorders
- Birth, Development, and Health
- Pediatric health and respiratory diseases
- Pregnancy and preeclampsia studies
- Intestinal Malrotation and Obstruction Disorders
- Child Nutrition and Water Access
- Celiac Disease Research and Management
- Asthma and respiratory diseases
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Microscopic Colitis
- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Food Allergy and Anaphylaxis Research
- Neonatal Health and Biochemistry
- Gastrointestinal motility and disorders
Emma Kinderziekenhuis
2015-2024
Amsterdam University Medical Centers
2018-2024
University of Amsterdam
2018-2024
National Institute for Public Health and the Environment
2024
Amsterdam UMC Location University of Amsterdam
2015-2023
University Medical Center Utrecht
2021-2023
Wilhelmina Children's Hospital
2021-2023
Vrije Universiteit Amsterdam
1999-2021
Utrecht University
2021
Nutricia Research (Netherlands)
2012-2019
We describe the effect on neonate of administration rituximab to a woman with idiopathic thrombocytopenic purpura (ITP). Rituximab, an anti-CD20 antibody, was given weekly for 4 weeks ITP in her third trimester pregnancy. One month after last healthy girl born. She had normal growth and development during first six months. At birth, B-lymphocytes were not detectable. Rituximab levels mother 24000 6700 ng/mL, respectively. Only 7 cases pregnancy described. No adverse events are described...
The functional integrity of the small bowel is impaired in coeliac disease. Intestinal permeability, as measured by sugar absorption test probably reflects this phenomenon. In a solution lactulose and mannitol was given to fasting patient lactulose/mannitol ratio urine collected over period five hours. performed nine patients with disease an abnormal jejunum on histological examination, 10 relatives aspecific symptoms but no villous atrophy, six gastrointestinal 22 healthy controls determine...
INTRODUCTION The use of azathioprine (AZA) in the treatment autoimmune diseases during pregnancy are believed to be relatively safe, particularly taking into account potential risks for mother and fetus should underlying disease become active due withdrawal this thiopurine. However, essential evidence on safety AZA is lacking. determination intrauterine exposure maternal may provide additional crucial insights teratogenicity drug. METHODS We describe three patients with Crohn's hepatitis who...
<h3>Objective</h3> Several studies have demonstrated a favourable safety profile for thiopurine use inflammatory bowel disease (IBD) during pregnancy. We performed study in pregnant patients with IBD who were using thiopurines, order to determine the influence of pregnancy on metabolism and assess intrauterine exposure fetus thiopurines. <h3>Design</h3> Female receiving steady-state thiopurines planning prospectively enrolled. 6-Thioguanine nucleotide (6-TGN) 6-methylmercaptopurine (6-MMP)...
Gut organoids are stem cell derived 3D models of the intestinal epithelium that useful for studying interactions between enteric pathogens and their host. While organoid model has been used both bacterial viral infections, this is a closed system with luminal side being inaccessible without microinjection or disruption polarization. In order to overcome simplify applicability transepithelial studies, permeable membrane based monolayer approaches needed. paper, we demonstrate method...
To determine the relation between intestinal permeability and birth weight, gestational age, postnatal perinatal risk factors in neonates.Intestinal was measured by sugar absorption test within two days of three to six later preterm healthy term infants. In test, urinary lactulose/mannitol ratio is after oral ingestion a solution (375 mosm) lactulose mannitol.A first performed 116 (26-36 weeks gestation) 16 A second 102 nine infants, not related age (r = -0.09, p 0.32) or weight 0.07, 0.43)....
Maternal antibodies, transported through the placenta during pregnancy, contribute to protection of infants from infectious diseases first months life. The aim this study was measure concentration antibodies against several vaccine-preventable in paired maternal and cord blood serum samples preterm term assess placental transfer ratios infant antibody concentrations diseases.Antibody specific pertussis proteins (pertussis toxin, filamentous hemagglutinin, pertactin, fimbriae), diphtheria...
ABSTRACT A premature infant in a neonatal intensive care unit (NICU) developed bloodstream infection caused by coagulase-negative staphylococci (CoNS) sensitive to vancomycin. The persisted for 3 weeks, despite therapy with vancomycin and replacement of all intravenous catheters. neonate died due necrotizing enterocolitis which during the ongoing sepsis. We screened this strain 216 other strains CoNS from cultures blood obtained neonates between 1997 2000 heteroresistance Forty-eight...