A5101963762- COVID-19 Clinical Research Studies
- Orthopaedic implants and arthroplasty
- Trauma and Emergency Care Studies
- Pelvic floor disorders treatments
- Long-Term Effects of COVID-19
- Pelvic and Acetabular Injuries
- Microencapsulation and Drying Processes
- Inhalation and Respiratory Drug Delivery
- Total Knee Arthroplasty Outcomes
- Urinary Bladder and Prostate Research
- Autophagy in Disease and Therapy
- Phase Equilibria and Thermodynamics
- Rabies epidemiology and control
- Functional Brain Connectivity Studies
- COVID-19 and healthcare impacts
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Orthopedic Infections and Treatments
- Tryptophan and brain disorders
- Healthcare professionals’ stress and burnout
- Air Quality and Health Impacts
- Viral Infections and Outbreaks Research
- Lower Extremity Biomechanics and Pathologies
- Neuroscience and Neuropharmacology Research
- Blood transfusion and management
- Neuroinflammation and Neurodegeneration Mechanisms
Peking University People's Hospital
2018-2025
Peking University
2018-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Peking Union Medical College Hospital
2023-2025
China Medical University
2008-2025
Xidian University
2025
Langfang Normal University
2025
Hebei Medical University
2022-2024
Institute of Forensic Science
2022-2024
Weatherford College
2023
Diabetes is a risk factor for the progression and prognosis of coronavirus disease (COVID-19), but relationship between glycosylated hemoglobin (HbA1c) level, inflammation, COVID-19 patients has not been explored.This was retrospective study who underwent an HbA1c test. Their demographic data, medical history, signs symptoms COVID-19, laboratory test results, final outcomes treatment were collected analyzed.A total 132 included divided into three groups based on their blood glucose status....
Adolescents and young adults are considered a high-risk group for internet gaming disorder (IGD). Early screening individuals with IGD exploring the underlying neural mechanisms is an effective strategy to reduce harm of IGD. We recruited 219 non-internet addicted college students evaluated them magnetic resonance imaging, followed by two-year longitudinal follow-up. used functional connectome gradient (FCG) capture macroscopic hierarchical organization human brain. Canonical correlation...
To evaluate the mental health status, stressors and self-adjustment of nurses in isolation wards at different periods Wuhan, China.Mental issues easily occurred among frontline medical workers a major epidemic. However, psychological adjustments experienced by have not been well described. This is crucial to improving clinical quality nursing safety ensuring nurses' physical health.We performed cross-sectional prospective study using Self Reporting Questionnaire-20, stressor questionnaire...
Post-traumatic stress disorder (PTSD) is a stress-related mental caused by traumatic experience. Single-prolonged (SPS) one of the animal models proposed for PTSD. Rats exposed to SPS showed enhanced inhibition hypothalamo-pituitary-adrenal (HPA) axis, which has been reliably reproduced in patients with Mineralocorticoid receptor (MR) and glucocorticoid (GR) hippocampus regulate HPA axis negative feedback. Abnormalities feedback are found PTSD, suggesting that GR MR might be involved...
Objective.To develop and externally validate habitat-based MRI radiomics for preoperative prediction of the EGFR mutation status based on brain metastasis (BM) from primary lung adenocarcinoma (LA).Approach.We retrospectively reviewed 150 38 patients hospital 1 2 between January 2017 December 2021 to form a an external validation cohort, respectively. Radiomics features were calculated whole tumor (W), active area (TAA) peritumoral oedema (POA) in contrast-enhanced T1-weighted (T1CE)...
Trauma Center, Peking University People's Hospital, National Center for Medicine, Key Laboratory of and Neural Regeneration (Ministry Education), Beijing, China *Corresponding author. Address: No.11 South Xizhimen Street, Beijing 100044, China. Tel: +86 010 86491374. E-mail: [email protected] (Z. Du). Sponsorships or competing interests that may be relevant to content are disclosed at the end this article. This is an open access article distributed under terms Creative Commons...
Surgical planning can be highly complicated and personalized, where a surgeon needs to balance multiple decisional dimensions including surgical effectiveness, risk, cost, patient's conditions preferences. Turning artificial intelligence is great appeal. This study filled in this gap with Multi-Dimensional Recommendation (MUDI), an interpretable data-driven intelligent system that supported personalized recommendations on both the surgeon's side joint consideration of dimensions. Applied...
Introduction Recent guidelines suggest behavioural weight loss (BWL) and pelvic floor muscle training (PFMT) as first-line treatment approaches for women with both obesity stress urinary incontinence (SUI). However, the optimal therapeutic management strategies these populations remain uncertain. Methods analysis This assessor-blinded parallel-group randomised controlled trial aims to compare efficacy of BWL alone, plus conventional PFMT a biofeedback device who are overweight or obese...
Ginkgo flavonoids were extracted from biloba leaves using supercritical carbon dioxide extraction technology (SFE) with ethanol as the entrainer. The effects of important process parameters on SFE examined, and crude extracts further refined. At optimized experimental conditions, i.e., 20 MPa pressure, a 40 °C temperature, 10 g/min CO2 flow rate, 6 mL/min yield could reach 0.36%. Supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer (SAA-HCM) was used to obtain...
The widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity ongoing treatments prompted us to develop a unique rat model combining ovariectomy simulated vaginal delivery. We hypothesized that tissue changes caused by low hormone levels mechanical stretch could complement each other. Thus, combined can potentially mimic collagen metabolism wall as well properties disease progression in POP. Ovariectomy with sequential delivery was performed on rats modeling group. Sham surgeries...
Abstract Polyether‐ether‐ketone (PEEK) is a potential alternative to metal alloys for use in the orthopedic implants; however, an vivo study appropriate animal model essential and has not yet been initiated. The aim of present was gather some preliminary evidence regarding performance safety cemented PEEK‐based knee replacement device goat model. Fifteen adult goats were randomly divided into two groups; control group ( n = 5), which received sham operation, experimental 10), total...
Polyether-ether-ketone (PEEK), cobalt-chromium-molybdenum (CoCrMo), and highly cross-linked polyethylene (HXLPE) are biomaterials used in orthopedic implants; their wear particles considered to induce peri-implant osteolysis. We examined whether different particle types the same degree of osteolysis.Forty female rabbits were randomly divided into four groups-the control group (n = 10), which received implantation operation sham at 1 month postoperation; three experimental groups 10 each...
Polyether-ether-ketone (PEEK) has been used clinically for intervertebral fusion and internal fixators in spine trauma surgery because of its mechanical properties bioinertness. The present study aimed to assess the suitability PEEK as an alternative material cobalt-chromium-molybdenum alloy total knee arthroplasty (TKA) evaluate vivo wear property on contact surface PEEK-on-highly cross-linked polyethylene (HXLPE). prosthesis was designed manufactured using injection molding based computed...
BACKGROUND: A pandemic of coronavirus disease (COVID-19) has been declared by the World Health Organization (WHO) and caring for critically ill patients is expected to be at core battling this disease.However, little known regarding an early detection high risk fatality. METHODS:This retrospective cohort study recruited consecutive adult admitted between February 8 29, 2020, three intensive care units (ICUs) in a designated hospital treating COVID-19 Wuhan.The detailed clinical information...
Our study aimed to investigate whether geometrical features (size, shape, or alignment parameters) of the femoral condyle affect morphology trochlear groove.Computed tomography models 195 femurs (97 and 98 knees from male female subjects, respectively) were reconstructed into three-dimensional categorised four types groove based on position turning point in relation mechanical axis (types 45°, 60°, 75°, 90°). Only subjects with healthy included, whereas individuals previous knee trauma pain,...
The present study investigated the influence of ischemic postconditioning (I-postC) on adjustment renal injury after limb ischemia-reperfusion (I/R) injury, to elucidate mechanisms Toll-like receptor 4 (TLR 4)/NF-κB signaling pathway using histopathological and immunohistochemical methods. Male Sprague-Dawley rats were randomly assigned five groups (numbered from 1 5): sham group (Group 1, only anesthesia procedure was conducted without I/R), I/R 2, h reperfusion following ischemia under...