A5011679512- Vector-borne infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Zoonotic diseases and public health
- Systemic Sclerosis and Related Diseases
- Leptospirosis research and findings
- Dermatological diseases and infestations
- Systemic Lupus Erythematosus Research
- Salivary Gland Disorders and Functions
- Leprosy Research and Treatment
- Facial Nerve Paralysis Treatment and Research
- Phytochemistry Medicinal Plant Applications
- Autoimmune Bullous Skin Diseases
- Mollusks and Parasites Studies
- Heart Rate Variability and Autonomic Control
- Toxin Mechanisms and Immunotoxins
- Digital Imaging for Blood Diseases
- Evolution and Paleontology Studies
- Lymphatic System and Diseases
- SARS-CoV-2 and COVID-19 Research
- Study of Mite Species
- Frailty in Older Adults
- Healthcare and Venom Research
- Yersinia bacterium, plague, ectoparasites research
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018-2025
Universidade de São Paulo
2000-2024
Economie Publique
2023
Instituto Butantan
2019
Universidade Brasil
2000-2010
Universidad San Pedro
2002
Objective To determine the immunogenicity of third dose CoronaVac vaccine in a large population patients with autoimmune rheumatic diseases (ARD) and factors associated impaired response. Methods Adult ARD age-balanced/sex-balanced controls (control group, CG) previously vaccinated two doses received at D210 (6 months after second dose). The presence anti-SARS-CoV-2 S1/S2 IgG neutralising antibodies (NAb) was evaluated to vaccination (D210) 30 days later (D240). Patients controlled disease...
INTRODUCTION: The symptoms of Brazilian borreliosis resemble the clinical manifestations Lyme disease (LD). However, there are differences between two in terms epidemiological and laboratory findings. Primers usually employed to diagnose LD have failed detect Borrelia strains Brazil. OBJECTIVE: We aimed identify using a conserved gene that synthesizes flagellar hook (flgE) burgdorferi sensu lato. METHOD: Three patients presenting with erythema migrans positive histories were recruited for...
This paper reports a case of coinfection caused by pathogens Lyme disease and babesiosis in brothers. was the first borreliosis Brazil, acquired Cotia County, State São Paulo, Brazil. Both children had tick bite history, presented erythema migrans, fever, arthralgia, mialgia, developed positive serology (ELISA Western-blotting) directed to Borrelia burgdorferi G 39/40 Babesia bovis antigens, mainly IgM class antibodies, suggestive acute disease. Also, high frequencies antibodies B. observed...
The aim of this study was to evaluate the epidemiological, clinical and laboratorial profile patients with Baggio-Yoshinari Syndrome (BYS), who underwent internment at Instituto de Infectologia Emilio Ribas in São Paulo, Brazil, during period from July 1990 2006. BYS is a new Brazilian tick-borne disease caused by Borrelia burgdorferi sensu lato microorganisms that resembles features Lyme (LD), except for its particularities. From 60 patients' records positive serology B. done ELISA...
INTRODUÇÃO: A doença de Lyme (DL) é uma picada carrapato, causado pela espiroqueta Borrelia burgdorferi sensu lato, transmitida por carrapatos do complexo Ixodes ricinus, que promove múltiplas manifestações clínicas sistêmicas. No Brasil, síndrome diferente descrita e mimetiza sintomas DL, mas também se manifesta com alta frequência episódios recorrentes alérgicas imunológicas. É pelo carrapato Amblyomma cajennense o agente etiológico não cultivável forma atípica. Devido a essas...
The Atlantic Forest small mammal land fauna, except bats, and the abiotic factors that might have an influence on its composition, were studied in Itapevi County, State of Sao Paulo, a forested region, partly altered by antropic action, from January, 1995 to June, 1996. trapping effort consisted 2,888 trap-nights, resulting 4.6% success monthly trappings, for five consecutive days. During this period, 134 specimens captured, which 46.3% Didelphimorphia 53.7% Rodentia. Eleven species...
To evaluate the frequency of anti-collagen type V in humans with early systemic sclerosis (SSc) compared to defined SSc patients and healthy controls, since collagen was shown be overexpressed patients' skin there is no data concerning presence this antibody stages human SSc. Experimental studies showed that animal models immunized developed a disease similar (SSc), antibodies production, mainly post-immunization. Eighty-one female were included divided into two groups: early-SSc (18...
Descrevemos o primeiro caso brasileiro de Riquetsiose branda, agravada por monoartrite em joelho, adulto jovem picado carrapato na perna esquerda região Camburi, localizada no município São Sebastião, sul da costeira do estado Paulo, Mata Atlântica, Brasil. O paciente apresentou uma escara inoculação local picada carrapato, associada ao aumento ganglionar virilha esquerda, febre, poliartralgia, cefaleia e erupção macular. Vinte dias após episódio joelho direito. diagnóstico branda foi...
We describe the first Brazilian case of mild Rickettsiosis, complicated by knee monoarthri- tis, in young adult bitten a tick on his left leg Camburi zone, located São Sebastião municipality, southern coastal region State Paulo, Atlantic rainforest region, Brazil. The patient developed inoculation eschar at bite site associated with enlarged lymph nodes groin, fever, polyarthralgia, headache and macular rash. Twenty days after episode, he displayed monoarthritis right knee. diag- nosis...
Relata-se inusitado achado de micro-organismos, semelhantes às espiroquetas, móveis e diferentes morfologias tamanhos, identificados pela microscopia campo escuro, no sangue animais do Centro Bioterismo da Faculdade Medicina USP. As bactérias não crescem em meios habituais cultivo, são pouco coradas pelo Giemsa derivados prata, as provas sorológicas moleculares foram negativas para Borrelia Leptospira. A eletrônica revelou presença micro-organismos com morfologia Mycoplasma e, devido à sua...
Abstract Introduction Takayasu’s arteritis (TAK) patients are at an elevated risk of metabolic syndrome and cardiovascular diseases (CVD). Currently, there no well-validated biomarkers to assess this in population. Previous research different cohorts has linked serum levels osteoprotegerin (OPG) its polymorphisms accelerated atherosclerosis a marker poor prognosis CVD. Thus, we assessed protein as potential biomarker CVD TAK patients. Objectives To evaluate the OPG SNPs (single nucleotide...
Compared to classic Lyme disease (LD), Baggio-Yoshinari syndrome (BYS) has the following distinctive characteristics: it is transmitted in Amazon area and Northeast, Central-West, Southeast, South regions of Brazil by hard ticks, notably
Lyme disease, a zoonotic infection caused by the bacterium
Lyme-borreliosis (LB) is a tick-borne disease prevalent in many parts of the world, yet it remains largely unknown. This lack awareness poses significant challenges for surveillance and diagnosis, requiring integrating epidemiological clinical information. Additionally, limited specificity low titers serological tests further complicate diagnostic process. To address these issues, we investigated molecular fine IgM antibody responses to five surface proteins B. burgdorferi. Materials...
Brazilian borreliosis (BB) disease is an infectious transmitted by ticks that mimics Lyme (LD) from the Northern Hemisphere. The BB clinical picture characterized a pathognomonic skin lesion (migratory erythema) and joint, neurological, cardiac psychiatric symptoms. Innate Th1/Th17 adaptive immunity seem to play important role in pathogenesis of disease. aim this study was characterize innate patients with acute (<3 months) convalescent (>3 Fifty (28 22 disease) without treatment 30 healthy...