A5100349608- Advanced Numerical Analysis Techniques
- Computational Geometry and Mesh Generation
- Advanced machining processes and optimization
- Nanoparticle-Based Drug Delivery
- 3D Shape Modeling and Analysis
- Computer Graphics and Visualization Techniques
- Numerical methods in engineering
- Iron oxide chemistry and applications
- Dendrimers and Hyperbranched Polymers
- Simulation and Modeling Applications
- Computational Fluid Dynamics and Aerodynamics
- Advanced Measurement and Detection Methods
- Fluid Dynamics and Turbulent Flows
- Image and Object Detection Techniques
- Digital Filter Design and Implementation
- Speech and Audio Processing
- Optical measurement and interference techniques
- Advanced Harmonic Analysis Research
- Neurobiology and Insect Physiology Research
- Drug Transport and Resistance Mechanisms
- Polymer Surface Interaction Studies
- Mathematical Biology Tumor Growth
- Advanced Vision and Imaging
- Invertebrate Immune Response Mechanisms
- Advanced Polymer Synthesis and Characterization
Zhejiang University of Finance and Economics
2021
Wuhan University
2005-2020
Carnegie Mellon University
2012-2017
University of Science and Technology of China
2016
Beijing University of Technology
2010
Significance We perform a tissue-scale, personalized computer simulation of prostate cancer (PCa) growth in patient, based on prostatic anatomy extracted from medical images. To do so, we propose mathematical model for the PCa. The includes an equation reference biomarker PCa: prostate-specific antigen (PSA). Hence, can link results our to data that urologists easily interpret. Our reproduces features tumor observed experiments and clinical practice. It also captures known shift pattern PCa,...
We present a hybrid variational-collocation, immersed, and fully-implicit formulation for fluid-structure interaction (FSI) using unstructured T-splines. In our immersed methodology, we define an Eulerian mesh on the whole computational domain Lagrangian solid domain, which moves arbitrarily top of mesh. Mathematically, problem reduces to solving three equations, namely, linear momentum balance, mass conservation, condition kinematic compatibility between displacement velocity. use weighted...
A reduction-sensitive graft polymer PHEA-S-S-C16 with poly{α,β-[N-(2-hydroxyethyl)-L-aspartamide]} (PHEA) as a backbone and disulfide-containing alkyl side chain (HOOC-S-S-C16 ) is synthesized evaluated for intracellular DOX delivery. can self-assemble into micelles in aqueous media load at total content of 7.3%. In vitro release studies reveal that the rate from accelerated presence DTT. The results cell experiments indicate DOX-loaded mPEG-S-S-C16 achieve rapid HeLa cells, compared their...
Abstract To generate analysis-suitable T-splines for arbitrary topologies, in this paper we introduce a new method to deal with extraordinary nodes the T-mesh. Knot interval duplication is used extract knot vectors and spoke nodes. From defined bicubic weighted T-spline basis functions, extracted Bezier coefficients are modified obtain gap-free surface. The boundaries shared by first-ring neighboring elements C0-continuous. Then use biquartic functions optimized increase surface continuity...
Porous hematite nanorods (PHNRs) are potential candidates as drug delivery carriers because of their pores which available for the encapsulation drugs and genes, large surface area loading biomacromolecules, biocompatibility, storage stability inexpensive large-scale preparation. We report a facile synthesis PHNRs loaded with poorly water-soluble drug, paclitaxel (PTX). were used templates precipitation PTX in dimethyl sulfoxide (DMSO)-water mixture. The amorphous was characterized by...
The conversion matrix between Beta-spline basis functions and Bézier representation is analyzed in this paper. Based on it, calculation of arbitrary degree can be translated into a solution linear system equations. construction simplified greatly, which made it more suitable for implement pervasive computing.
This paper presents a software of effectiveness evaluation for space debris cataloguing developed by the research group Wuhan University. Firstly, background and related concepts are introduced. Then, interface, structure functions described. The is applied to evaluate simulated surveillance network in its 99 LEO objects, contributions individual sensors obtained. can play an important role design