Skin burn wound is a notable medical burden worldwide. Rapid and effective treatment of burnt skin vital to fasten closure healing properly. Amniotic graft Aloe vera are widely used as managing biomaterials. Sophisticated processing, high cost, availability, the requirement medics for transplantation limit application amnion grafts. We aim prepare novel gel from combined with extract which overcome limitations graft.Two percent human amniotic membrane (AM), (AV) AM+AV gels were prepared. In...

Fabrication of scaffolds from biomaterials for restoration defected mandible bone has attained increased attention due to limited accessibility natural grafting. Hydroxyapatite (Ha), collagen type 1 (Col1) and chitosan (Cs) are widely used which could be fabricated as a scaffold overcome the paucity substitutes. Here, rabbit Col1, shrimp Cs bovine Ha were extracted characterized with respect physicochemical properties. Following biocompatibility, degradability cytotoxicity tests Ha, Col1...

BACKGROUND:A burn wound is one of the most frequent and devastating injuries for patients which requires extensive care. Early treatment wounds improves healing significantly. OBJECTIVE:This study was designed to investigate efficacy amnion collagen-based hydrogels on cutaneous b urn in rats with covering membrane. METHODS:We prepared a novel cell free hydrogel comprising human amnion, rabbit collagen, carboxymethyl cellulose sodium salt, citric acid, methyl paraben, propyl glycerin...

ABSTRACT We determined the mode of action nukacin ISK-1. It did not cause membrane potential dissipation or efflux ATP K + ions from cells a sensitive bacterial strain; however, it blocked depolarization activity nisin. Nukacin ISK-1-treated had single arrangements without formation complete septum. A remarkable reduction in cell wall width was also observed, but cytoplasmic content unaffected. concluded that ISK-1 is bacteriostatic.

Hydroxyapatite (HA) was extracted from bovine and human cortical bone by thermal decomposition process characterized using several analytical tools, including thermo-gravimetric analysis (TGA), X-ray diffraction (XRD), fluorescence (XRF), Flourier transformed infrared spectroscopy (FTIR) scanning electron microscopy (SEM).Removal of organic matter the confirmed TGA.XRD data that HA only crystalline phase when sintered at 950 °C.XRF revealed calcium phosphorus were main components magnesium,...

Abstract Recently, the fabrication of a scaffold from biomaterials has been increased due to lack adequate natural bone for grafting. In this study, hydroxyapatite-chitosan-alginate-polyamide (HCAP) synthetic was fabricated using thermally induced phase separation (TIPS) technique. The cross-linked with either chemical cross-linker (calcium chloride, 2-hydroxyethyl methacrylate (HEMA), or glutaraldehyde (GTA)) physical (gamma irradiation (IR)) resulting in scaffolds HCAP-CaCl 2 , HCAP-HEMA,...

Burn has terrible consequences for the affected patients, making them vulnerable to wound infections and septicemia, which results in physical mental disability death, necessitating superior treatment options. Human amniotic membrane (HAM) been utilized burn wounds decades its low immunogenicity, angiogenic, anti‐inflammatory, antimicrobial properties promoting epithelialization. Silver nanoparticles (AgNPs), on other hand, have promote fibroblast migration. This study aimed determine...

ABSTRACT The antibacterial activities and membrane binding of nukacin ISK-1 its fragments mutants were evaluated to delineate the determinants governing structure-function relationships. tail region (nukacin 1-7 ) ring 7-27 shown have no activity also had synergistic effect on each other or even ISK-1. Both a fragment with three lysines in N terminus deleted 4-27 mutant replaced alanine (K1-3A ISK-1) imparted very low (32-fold lower than exhibited similar antagonistic Addition two lysine...

Over the last decades, hydroxyapatite (HA) and its composite with biopolymer have been extensively developed applied in biomedical application.The aim of this study is to produce a novel 3D porous HA scaffolds for bone tissue regeneration.Scaffolds varying composition HA, chitosan, gelatin, agarose poly vinyl alcohol (PVA) were prepared using freeze drying method.The scaffold was analyzed determine density, porosity, biodegradability, swelling kinetics, morphology structural...

Hydroxyapatite (HA) was extracted from bovine and human cortical bone by thermal decomposition process characterized using several analytical tools, including thermo-gravimetric analysis (TGA), X-ray diffraction (XRD), fluorescence (XRF), Flourier transformed infrared spectroscopy (FTIR) scanning electron microscopy (SEM).Removal of organic matter the confirmed TGA.XRD data that HA only crystalline phase when sintered at 950 °C.XRF revealed calcium phosphorus were main components magnesium,...

Bone tissue engineering aims to repair diseased or damaged bone that cannot be regenerated naturally. This study is designed develop biodegradable porous scaffolds as substitutes and evaluate the effect of gamma irradiation on these for restoration defected bone. Here, composite (HA-COL-CS-Mg-ZnO) were prepared by thermally induced phase separation (TIPS) technique using collagen (COL) chitosan (CS), hydroxyapatite (HA), magnesium (Mg), zinc oxide (ZnO) at different mass ratios. Thereafter,...

Abstract: The aim of this study is to emphasize on the clinical uses amniotic membrane (AM) in multiple ocular disorders. AM possesses many properties including promotion epithelialization, anti-fibrotic, anti-apoptotic, anti-angiogenic properties. Epithelial wound healing eye surface promoted due several epidermal and keratocyte growth factors as well by its anti-inflammatory anti-scarring effects interleukin-10, interleukin-1 receptor antagonists inhibition transforming factor- beta...

Organic solar cell draws attention because of its low cost and constantly increasing efficiency. Though having many advantages, power conversion efficiency hinders organic photovoltaic cells from their commercialization. Tandem combine two or more single junction complementary absorption band undoubtedly provide an effective means to uplift the cells. In this paper, we analyze performance three individual Single PCDTBT:PCBM shows 6.02% whereas PMDPP3T:PCBM pBBTDPP2:PCBM 5.99% 3.15%...

The development of biocompatible scaffolds is rapidly growing in several fields human health, particularly for the treatment bone defects. In this study, silver nanoparticle (AgNPs)-incorporated hydroxyapatite (HA), chitosan (Chi), and polyvinylpyrrolidone (PVP)-based were fabricated using freeze-drying method tissue engineering. Physicochemical properties such as porosity, density, swelling ratio, biodegradability, well blood biocompatibility, brine shrimp lethality, antibacterial...