- Cellular Mechanics and Interactions
- Nuclear physics research studies
- Theoretical and Computational Physics
- Quantum Chromodynamics and Particle Interactions
- Microfluidic and Bio-sensing Technologies
- Pickering emulsions and particle stabilization
- Atomic and Molecular Physics
- 3D Printing in Biomedical Research
- Gene Regulatory Network Analysis
- Micro and Nano Robotics
- Scientific Research and Discoveries
- Particle physics theoretical and experimental studies
- Diffusion and Search Dynamics
- Black Holes and Theoretical Physics
- Developmental Biology and Gene Regulation
- Nonlinear Dynamics and Pattern Formation
- Slime Mold and Myxomycetes Research
- Material Dynamics and Properties
- Radiation Therapy and Dosimetry
- Mathematical Biology Tumor Growth
- Block Copolymer Self-Assembly
- stochastic dynamics and bifurcation
- Advanced Thermodynamics and Statistical Mechanics
- Stochastic processes and statistical mechanics
- Advanced Chemical Physics Studies
Universidade Federal do Rio Grande do Sul
2006-2024
Indiana University Bloomington
2012
Biocom
2012
Kyungdong University
2010
University of Leeds
2005
University of Notre Dame
2003-2004
University of Cologne
1997-1998
University of Cambridge
1972-1973
King's College London
1969-1971
The King's College
1971
Abstract Motivation: CompuCell is a multi-model software framework for simulation of the development multicellular organisms known as morphogenesis. It models interaction gene regulatory network with generic cellular mechanisms, such cell adhesion, division, haptotaxis and chemotaxis. A combination state automaton stochastic local rules set differential equations, including subcellular ordinary equations extracellular reaction–diffusion partial model regulation. This in turn controls...
A self-propelled particle model is introduced to study cell sorting occurring in some living organisms. This allows us evaluate the influence of intrinsic motility separately from differential adhesion with fluctuations, a mechanism previously shown be sufficient explain variety rearrangement processes. We find that tendency cells actively follow their neighbors greatly reduces segregation time scales. finite-size analysis process reveals clear algebraic growth laws as physical...
The actions of cell adhesion molecules, in particular, cadherins during embryonic development and morphogenesis more generally, regulate many aspects cellular interactions, regulation signaling. Often, a gradient cadherin expression levels drives collective relative motions generating macroscopic sorting. Computer simulations sorting have focused on the interactions cells with only few discrete between cells, ignoring biologically observed continuous variations possible nonlinearities...
Tumor cells and structure both evolve due to heritable variation of cell behaviors selection over periods weeks years (somatic evolution). Micro-environmental factors exert pressures on tumor-cell behaviors, which influence the rate direction evolution specific especially development aggression resistance chemotherapies. In this paper, we present, step-by-step, a multi-cell, virtual-tissue model tumor somatic evolution, simulated using open-source CompuCell3D modeling environment. Our...
We perform extensive Potts model simulations of three-dimensional dry foam coarsening. Starting with 2.25 million bubbles, we have enough statistics to fulfill the three constraints required for study statistical scale invariance: first, time transient end and reach scaling state; then, in state itself characterize its properties; finally, bubbles at avoid spurious finite size effects. In state, find that average surface area increases linearly time. The geometry (bubble shape size) topology...
We study the topology and geometry of two dimensional coarsening foams with arbitrary liquid fraction. To interpolate between dry limit described by von Neumann's law, wet Marqusee equation, relevant bubble characteristics are Plateau border radius a new variable, effective number sides. propose an equation for individual growth rate as weighted sum through bubble-bubble interfaces bubble-Plateau borders interfaces. The resulting prediction is successfully tested, without adjustable...
A six-parameter optical model for proton elastic scattering from $^{40}\mathrm{Ca}$ has been developed in which the real part of potential generated a matter distribution that reproduces single-particle binding energies and electron elastic-scattering cross sections. Gaussian nucleon-nucleon force used an optimum range 4.5 \ifmmode\pm\else\textpm\fi{} 0.4 ${\mathrm{fm}}^{2}$ extracted. Improved fits are obtained with density-dependent effective interaction.
The structure of the N=Z nuclei 60Zn, 62Ga, 64Ge and 72Kr has been investigated at GASP spectrometer through 32S + 40Ca reactions 140 160 MeV, respectively, using reaction channel selection with ISIS Si-ball. high spin states such have searching for four quasi-particle g92 alignment. TRS calculations performed N=36, 38 40 Kr isotopes. In case alignment is observed to be significantly delayed in rotational frequency respect heavier Such a delay contradicts predictions mean field may...
Motivation: Monte Carlo methods are the most effective means of exploring energy landscapes protein folding. The rugged topography folding causes sampling inefficiencies however, particularly at low, physiological temperatures.