- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Treatment of Major Depression
- Migration, Health and Trauma
- Mental Health Treatment and Access
- Child Abuse and Trauma
- COVID-19 and Mental Health
- Obsessive-Compulsive Spectrum Disorders
- Eating Disorders and Behaviors
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Health and Mental Health
- Healthcare Decision-Making and Restraints
- Digital Mental Health Interventions
- Mental Health Research Topics
- Health Services Management and Policy
- Health, psychology, and well-being
- Long-Term Effects of COVID-19
- Education and experiences of immigrants and refugees
- Attention Deficit Hyperactivity Disorder
- Body Image and Dysmorphia Studies
- Medical Research and Practices
- Chronic Disease Management Strategies
- Maternal Mental Health During Pregnancy and Postpartum
University of Campania "Luigi Vanvitelli"
2022-2025
Policlinico Umberto I
2021
Sapienza University of Rome
2021
Purpose of review Major depressive disorder (MDD) is a common and burdensome severe mental disorder, which expected to become the leading cause disease burden worldwide. Most patients with MDD remain untreated/undertreated. For many decades “a trial error” approach has been adopted for selecting best treatment plan each individual patient, but more recently personalized proposed, by taking into account several clinical factors (e.g., stage, comorbidity, duration illness). Therefore, aim this...
Treatment-resistant depression (TRD) occurs when at least two different antidepressants, taken the right dosage, for adequate period of time and with continuity, fail to give positive clinical effects. Esketamine, S-enantiomer ketamine, was recently approved TRD treatment from U.S. Food Drug Administration European Medicine Agency. Despite proved efficacy, many misconceptions by clinicians patients accompany this medication. We aimed review most common "false myths" regarding esketemine,...
Affective temperaments represent the stable, biologically determined substrates of mood disorders. The relationship between affective and bipolar disorder (BD) or major depressive (MDD) has been described. However, strength such should be tested while considering other factors influencing diagnosis BD/MDD. Literature also lacks a comprehensive description interplay temperament characteristics aim present study is to address these issues.This multicentric observational including 7 Italian...
Background/Objectives: Bipolar disorder (BD) and obsessive-compulsive (OCD) often coexist, presenting significant challenges in treatment. OCD comorbidity BD is associated with severe clinical features such as increased suicidality impaired functioning. While selective serotonin reuptake inhibitors (SSRIs) are effective for OCD, they may increase manic shifts patients. The use of long-acting injectable (LAI) antipsychotics monthly aripiprazole (ARI-LAI) paliperidone (PP-LAI) has been...
Suicide ideation and behaviors are major health issues in the field of mental health. Several psychological psychosocial factors have been taken into account as possible predictors suicidality. Only recently affective temperaments considered linked to suicide. This study aims investigate relationship between suicidality, including lifetime onset suicide ideation, presence attempts total number attempts. is a naturalistic multicentric observational study, involving outpatient units seven...
Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such vulnerable population.
After the reform of mental health care system approved in 1978, structure and organization Italian has represented an innovative model care, shifting from asylum-based to community-based model, with gradual closure all hospitals. According 2023 Mental Health Report, issued every year by Ministry Health, more than 700.000 people is suffering severe disorders. The burden on services highly demanding, estimate 9 million provided patients. With shift responsibility for healthcare was moved...
On January 30, 2020, the World Health Organization (WHO) declared status of pandemic due to COVID-19 infection. The initial phases were characterized by uncertainty and public fears. In order cope with such unexpected conditions, people adopted different coping strategies, including search for information, accessing Internet, using social media. present study based on COMET collaborative research network aims to: (1) assess use Internet media among Italian general population; (2) explore...
The relationship between childhood maltreatment and eating disorder psychopathology has been under-investigated. purpose of this study was to investigate the role alexithymia in mediating experiences (ED) symptoms. One-hundred-forty-three women with anorexia nervosa, 110 bulimia nervosa 108 healthy filled Eating Disorder Inventory-2, Childhood Trauma Questionnaire Toronto Alexithymia Scale-20 (TAS-20). A mediator path model including trauma types as predictors, subscales TAS-20 mediators ED...
Abstract This multicentric randomized controlled trial (RCT), carried out in six Italian University mental health sites, aims to test the efficacy of a six-month psychosocial intervention (LYFESTYLE) on Body Mass Index (BMI), body weight, waist circumference, fasting glucose, triglycerides, cholesterol, Framingham and HOmeostasis Model Assessment insulin resistance (HOMA-IR) indexes patients with schizophrenia, bipolar disorder, major depression. Moreover, has also been tested several other...
Immigrants in Europe appear to be at higher risk of psychiatric coercive interventions. Involuntary hospitalization poses significant ethical and clinical challenges. Nonetheless, reasons for migration other factors involuntary treatment were rarely addressed previous studies. The aims this study are clarify whether immigrant patients with acute mental disorders involuntarily admitted hospital explore migratory associated treatment.In cross-sectional matched sample study, we compared the...
The present study aims to assess clinical and psychological correlates of functioning in patients with mood disorders, a naturalistic setting. In particular, we aimed describe which sociodemographic, clinical, temperamental dispositions are more frequently associated poor functioning, the association between cognitive euthymic major depression bipolar disorder.Inclusion criteria were as follows: (1) diagnosis depression, or disorder type I II; (2) age 18 65 years; (3) being stable phase...
This study aims to assess the efficacy of a psychoeducational family intervention (PFI) reduce severity depressive symptoms and improve psychosocial functioning increase social contacts in sample patients with major disorder (MDD). The degree which PFI will patients' relapses, hospitalizations, self-stigmatization their quality life also be assessed. Other secondary outcomes include improvement relatives' coping strategies, burden, expressed emotions life. non-profit, unfunded, national,...