- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Eating Disorders and Behaviors
- Neurological disorders and treatments
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Parkinson's Disease Mechanisms and Treatments
- Schizophrenia research and treatment
- Congenital heart defects research
- Botulinum Toxin and Related Neurological Disorders
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Body Image and Dysmorphia Studies
- Suicide and Self-Harm Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health and Psychiatry
- Genetic Neurodegenerative Diseases
- Cancer survivorship and care
- Connective tissue disorders research
- Mental Health Research Topics
- Tryptophan and brain disorders
- Personality Disorders and Psychopathology
- Mental Health Treatment and Access
- Attention Deficit Hyperactivity Disorder
- Sexuality, Behavior, and Technology
Sapienza University of Rome
2015-2025
Sydney Local Health District
2021
Western Sydney University
2021
Policlinico Umberto I
2012-2021
Nepean Hospital
2021
The University of Sydney
2021
Creative Research Enterprises (United States)
2018
Istituto Neurologico Mediterraneo
2015
Yale University
2014
University of Pavia
2012
There is now evidence that repeated administration of interferon-α (IFN-α) to patients with chronic active hepatitis and cancers induces depressive symptoms. also induction the cytokine network modulates serotonergic system major depression related activation disturbances in metabolism. The aims this study were examine effects IFN-α–based immunotherapy on development symptoms relation its plasma tryptophan kynurenine serum serotonin (5-HT). Eighteen affected by C treated IFN-α (3–6 million...
Abstract In a single‐center, case–control study, we investigated the frequency and types of psychiatric disturbances in 89 consecutive patients with various primary focal dystonias (34 had cervical dystonia (CD), 28 blepharospasm (BPS), 16 laryngeal (LD), 11 arm dystonia), 62 healthy control subjects as controls for BPS, 26 hemifacial spasm (HFS). Patients underwent full evaluation. Diagnosis was based on structured clinical interview DSM‐IV, obsessive‐compulsive disorder (OCD) assessed...
Cancer patients experience several stressors and emotional upheavals. Fear of death, interruption life plans, changes in body image self-esteem, social role lifestyle are all important issues to be faced. Moreover, Depressive Disorders may impact the course disease compliance. The cost prevalence, impairment caused, diagnostic therapeutic uncertainty surrounding depressive symptoms among cancer make these conditions a priority for research. In this article we discuss recent data, focusing on...
Symptoms of depression are transdiagnostic heterogenous features frequently assessed in psychiatric disorders, that impact the response to first-line treatment and associated with higher suicide risk. This study whether severe mental pain could characterize a specific phenotype severely depressed high-risk patients. We also aimed analyze differences treatments administered.2,297 adult patients (1,404 females 893 males; mean age = 43.25 years, SD 15.15) treated several Italian departments....
Objective: Mental pain and exposure to maltreatment are significant risk factors for suicidal behavior. This study aimed investigate whether mental could be associated with a recent suicide attempt it mediate the relationship between childhood traumatic experiences in psychiatric patients.Methods: A multicenter observational was organized as joint project representatives of numerous mixed Italian academic clinical settings. Between December 2017 March 2020, batteries tests were administered...
Although the association between problematic use of internet and eating disorders (EDs) in young adults has been previously established, its underlying mechanisms have not completely clarified. It suggested that exposure to idealized very thin toned body images (e.g., "thinspiration" "fitspiration" trends) on social media might lead increased feelings dissatisfaction which, turn, can represent a trigger for EDs. We tested this hypothesis sample (N = 721) (504 females, mean age: 24.13 ± 3.70...
According to the gender paradox in suicidology, an important sex difference has been reported with a preponderance of females nonfatal suicidal behavior and males completed suicide. Furthermore, present different risk factors for The study explored possible clinical differences between male female psychiatric inpatients who had recently attempted included 177 adult hospitalized following suicide attempt at University Psychiatric Clinic, Sant'Andrea Hospital, Sapienza Rome. Clinical features...
<i>Introduction:</i> Current psychiatric classification systems underestimate the part played by anger and aggressiveness in unipolar depression. This study was designed to assess relevance of anger, irritability, aggressiveness, hostility, psychomotor activation major depressive disorder. <i>Methods:</i> A total 222 newly admitted consecutive outpatients with disorder (mean age 48.9 years, 64.4% females) were enrolled study. They had no comorbid axis I or II DSM-IV...
We investigated primary motor cortex and brain stem plasticity in patients with Gilles de la Tourette syndrome. The study group comprised 12 syndrome 24 healthy subjects. Patients were clinically evaluated using the Yale Global Tic Severity Scale. tested cortical by conditioning left intermittent or continuous theta-burst stimulation 2 separate sessions. Test consisted of 20 motor-evoked potentials recorded from right first interosseous muscle before after stimulation. also supraorbital...
Our aim in this observational study was to evaluate the feasibility of a multiphasic screening project for detection and treatment mood anxiety disorders among cancer patients natural setting. One hundred sixty-five with cancer, consecutively admitted Oncology Division San Camillo-Forlanini Hospital, were recruited study. All had solid tumors; majority them colon, breast, lung cancers. completed Hospital Anxiety Depression Scale (HADS). Patients screened as positive administered following...
Gilles de la Tourette syndrome is characterized by motor/vocal tics commonly associated with psychiatric disorders, including obsessive-compulsive disorder. We investigated primary motor cortex and brainstem plasticity in patients, exposed unexposed to chronic drug treatment, without disturbances. also studied 20 patients disturbances, 15 disorder, healthy subjects. All groups included drug-naïve patients. conditioned the left intermittent/continuous theta-burst stimulation recorded evoked...
The objective of this study was to characterise international trends in the use psychotropic medication, psychological therapies, and novel therapies used treat obsessive-compulsive disorder (OCD).Researchers field OCD were invited contribute summary statistics on characteristics their samples. Consistency across countries evaluated.The surveyed 19 expert centres from 15 (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, United...