A5100779719- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Radiomics and Machine Learning in Medical Imaging
- Vestibular and auditory disorders
- Neuroscience and Neuropharmacology Research
- RNA regulation and disease
- Epilepsy research and treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Gastroesophageal reflux and treatments
- Gestational Trophoblastic Disease Studies
- CNS Lymphoma Diagnosis and Treatment
- Medical Device Sterilization and Disinfection
- Eosinophilic Esophagitis
- Hearing Loss and Rehabilitation
- Alzheimer's disease research and treatments
- Bone and Joint Diseases
- Neurological Disease Mechanisms and Treatments
- Anesthesia and Sedative Agents
- Ear Surgery and Otitis Media
- Cardiovascular and Diving-Related Complications
- Lymphoma Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Ectopic Pregnancy Diagnosis and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- S100 Proteins and Annexins
First Affiliated Hospital of GuangXi Medical University
2023-2025
Guangxi Medical University
2023-2025
State Key Laboratory of Oncology in South China
2022
Sun Yat-sen University
2022
Sun Yat-sen University Cancer Center
2022
The Seventh Affiliated Hospital of Sun Yat-sen University
2022
West China Medical Center of Sichuan University
2008
The aim of this study was to establish an iron overload rat model simulate the elevated levels in patients with thalassemia and investigate potential association between hippocampal deposition cognition. Two groups overloaded rats one group control were used for study. Morris water maze (MWM) test spatial reference memory indicated by escape latency time number MWM platform crossings. magnetic susceptibility value tissue, a measure deposition, assessed quantitative mapping (QSM) correlated...
To develop and validate a radiomics nomogram model for predicting the micropapillary pattern (MPP) in lung adenocarcinoma (LUAD) tumors of ≤2 cm size. In this study, 300 LUAD patients from our institution were randomly divided into training cohort (n = 210) an internal validation 90) at ratio 7:3, besides, we selected 65 another hospital as external cohort. The region interest tumor was delineated on computed tomography (CT) images, features extracted. A established using features, clinical...
Conclusions. Significant difference in the incidence of mitochondrial DNA (mtDNA) mutations was found between Chinese and USA populations. The identification mtDNA A1555G mutation a large proportion probands with nonsyndromic sensorineural hearing loss (NSHL) provides molecular explanation for high prevalence aminoglycoside-induced deafness China. Objective. aim to characterize audiological genetic features NSHL due mtDNA. Subjects methods. audiogram analyses were performed 498 patients (290...
Background and aim The clinical outcome of endoscopy submucosal dissection with subsequent radiotherapy for esophageal squamous cell carcinoma remain unclear. In this study we to investigate the efficacy safety endoscopic adjuvant in treatment superficial involving muscularis mucosae (T1a-MM) or submucosa < 200 μm (T1b-SM1). Methods We analyzed 20 patients pathologically confirmed T1a-MM T1b-SM1 treated by from 2016 2020 Lihuili Hospital, 9 received (RT group) 11 did not (non-RT group)....
Reliable predictors for rehabilitation outcomes in patients with congenital sensorineural hearing loss (CSNHL) after cochlear implantation (CI) are lacking. The purchase of this study was to develop a nomogram based on clinical characteristics and neuroimaging features predict the outcome children CSNHL CI.
Abstract Purpose Primary central nervous system post-transplantation lymphoproliferative disorder (PCNS-PTLD) is a rare but serious complication of hematopoietic stem cell transplantation (HSCT) in patients with severe β-thalassemia. This study aimed to assess the clinical presentation, pathological characteristics, neuroimaging findings, and treatment strategies β-thalassemia who developed PCNS-PTLD compare case series from our transplant center reported cases literature. Methods We...
Epithelioid trophoblastic tumor (ETT) is an extremely rare malignant gestational neoplasm commonly presenting with abnormal vaginal bleeding, abdominal pain, and increased human chorionic gonadotropin (hCG). This study reported a case of uterine ETT the main manifestation being hCG.
Objectives: To develop and validate a machine learning model based on dual-energy computed tomography (DECT) for predicting cervical lymph node metastases (CLNM) in patients diagnosed with nasopharyngeal carcinoma (NPC).Methods: This prospective single-center study enrolled NPC the assessment included both DECT 18F-fluorodeoxyglucose positron emission tomography/computed (18F-FDG PET/CT). Radiomics features were extracted from each region of interest (ROI) nodes using arterial venous phase...
Beta-thalassemia (β-TM) is an inherited blood disorder with severe anemia. In this study, we investigated alterations of T2 heterogeneity in cortical regions caused by β-TM using magnetic resonance imaging (MRI). Compared healthy controls, patients showed increased heterogeneities bilateral inferior orbitofrontal, left calcarine, cuneus and superior occipital lobe, while no decreased was observed. Thus, concluded that could reveal the β-TM-affecting brain.
Beta-thalassemia (β-TM) is a chronic blood disorder presenting with severe anemia. However, the abnormalities of microstructure in cortical regions are still unclear. Herein, we explored difference quantitative MRI parameters gray matter between β-TM patients and healthy controls. The results showed that altered T1 T2 values specific patients, which may be associated alteration brain matter, such as reduced myelin content excessive iron deposition. Thus, variables promising imaging markers...
Beta-thalassemia (β-TM) is a genetically haematological disorder leading to reduced production of hemoglobin. Yet its alterations in white matter (WM) microstructure remain unclear. The present study aimed analyze quantitative MRI parameters WM β-TM patients using synthetic MRI. results showed that T1, T2 and T1/T2 ratio widespread areas were affected by β-TM, which may be related iron deposition decrease myelin concentration. Thus, we concluded can revealed parameters.
Beta-thalassemia (β-TM) is an inherited blood disorder that causes the body to make less hemoglobin. In this study, we examined altered cortical susceptibility heterogeneity in patients with β-TM vs. healthy controls using magnetic resonance imaging (MRI). For regions of heterogeneities group, increase was only found left hippocampus, while decreased were observed for all other located frontal and temporal lobes. Thus, concluded could reveal β-TM-affecting regions.
Abstract Background For patients taking esophagogastroduodenoscopy (EGD), sedation should ideally be used individually based on patients’ comfort and tolerance level. However, currently there is no valid predictive tool. We undertook this study to develop temporally validate a self-assessment tool for predicting discomfort in Chinese undergoing EGD. Methods recruited 1522 routine diagnostic EGD without sedation. collected candidate predictor variables before endoscopy evaluated with 5-point...
The prevalence of fungal esophagitis (FE) has risen in various populations, with increased risk factors the disease including HIV infection and use immunosuppressive agents. FE been recognized increasingly over last few decades. This article reviews findings recent studies conclusions some mainstream guidelines to inform clinicians researchers this field.
Objective To investigate the clinical significance of restrictive foramen ovale (RFO) monitored by fetal echocardiography during middle to late stage pregnancy. Methods The detection rate, echocardiographic features and outcome in fetuses with RFO without cardiac malformations from 7 319 pregnant women received prenatal were retrospectively reviewed analyzed. Results RFO was found 40 (0.55%) fetuses. The inclusion criteria including a narrow right left shunt less than 2.5 mm...