- Appendicitis Diagnosis and Management
- Gastrointestinal motility and disorders
- Neuroendocrine Tumor Research Advances
- Ethics and Legal Issues in Pediatric Healthcare
- Child Abuse and Trauma
- Growth Hormone and Insulin-like Growth Factors
- Cell Adhesion Molecules Research
- Adolescent and Pediatric Healthcare
- Neonatal Respiratory Health Research
- Abdominal Surgery and Complications
- Advanced Glycation End Products research
- Child Nutrition and Feeding Issues
- Congenital gastrointestinal and neural anomalies
- Thyroid Disorders and Treatments
- Protease and Inhibitor Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Electronic Health Records Systems
- Neonatal and fetal brain pathology
- Pediatric Pain Management Techniques
- Healthcare Systems and Technology
- Neuroscience of respiration and sleep
- Primary Care and Health Outcomes
- Opioid Use Disorder Treatment
- Pelvic floor disorders treatments
- Child and Adolescent Health
Nationwide Children's Hospital
2012-2019
Center for Innovation
2019
The Ohio State University
1992-1996
Baylor College of Medicine
1986
Roswell Park Comprehensive Cancer Center
1986
Although opioids are an important component of pain management for children recovering from surgery, postoperative opioid prescribing has contributed to the current crisis in United States because these medications often prescribed excess and rarely properly disposed. One potential strategy combat misuse is remove circulation by providing patients with drug disposal products that enable safe home garbage.To determine whether provision a bag increases proper among families pediatric...
Abstract Objective To evaluate the long‐term efficacy of sacral nerve stimulation ( SNS ) in children with constipation and describe patient benefit parent satisfaction. Methods Using a prospective registry, we identified patients <21 years old treated for >2 years. We compared symptoms, medical treatment, PedsQL Gastrointestinal Symptom Scale GSS ), Fecal Incontinence Quality Life FIQL Severity Index FISI before at follow‐up. contacted parents to administer Glasgow Children's Benefit...
Strategies to activate and engage patients caregivers in shared decision making the acute care setting may result improved outcomes.
Somatostatin (SRIF, SRIF-14) is a known product of the normal and malignant parafollicular cell thyroid. In this report we characterize SRIF production by TT cells, line transformed calcitonin-producing cells derived from human medullary thyroid carcinoma. The were found to contain (5–12 ng/106 cells) secrete (3–10 cells.48 h) immunoreactive SRIF. Molecular sieve chromatography extracts under denaturing conditions showed major peak with mol wt slightly larger than 12,700, probably...
BackgroundSoluble RAGE (sRAGE) has been associated with multiple inflammatory responses including maternal chorioamnionitis and preeclampsia. Analysis of umbilical cord blood levels have also indicated that sRAGE in the infant are affected by inflammation. S100b is a ligand for increases circulating poor neurological outcome preterm infants. The objective this study was to determine whether or s100b plasma samples from extremely infants at end first week life were correlated morbidities time...
Objective To determine whether quality measures based on computer‐extracted EHR data can reproduce findings manually extracted by reviewers. Data Sources We studied 12 of care indicated for adolescent well‐care visits 597 patients in three pediatric health systems. Study Design Observational study. Collection/Extraction Methods Manual reviewers collected from the . Site personnel programmed their systems to extract same structured fields according national IT standards. Principal Findings...
The aim of this review is develop a reliable and valid questionnaire that assesses patient-reported experience measures (PREMs) outcome (PROMs) caregivers, families, patients with severe constipation fecal incontinence who failed conservative treatments require formal bowel management program (BMP).A 5-step iterative process was utilized to ensure the reliability validity final instrument. Parents or guardians undergoing our week-long BMP were first asked 20 open-ended questions aimed at...
There have been few studies of physiological importance on the regulation somatostatin by hormones. We studied effect synthetic glucocorticoid dexamethasone production in human medullary thyroid carcinoma TT cell line, a model for parafollicular cell. Dexamethasone inhibited dose-related manner with maximal at concentration 10(-6) M. cells treated (10(-6) M) showed an almost complete inhibition peptide 48 h treatment. Molecular sizing chromatography demonstrated decrease both probable...
To test the hypothesis that plasma lipid metabolite levels in premature infants are associated with development of bronchopulmonary dysplasia (BPD). The studies also tested a secondary were correlated gestational age.Infants born <32 weeks' gestation enrolled during first 72 h life. Plasma samples obtained and measured by LC-MS/MS. Clinical data collected to determine infant outcomes BPD diagnosis.Following adjustment for confounders, not BPD; however, specific metabolites age.Immature...
Preventive quality measures for the foster care population are largely untested. The objective of study is to identify healthcare young children and adolescents in test whether data required calculate these can be feasibly extracted interpreted within an electronic health records or Statewide Automated Child Welfare Information System. AAP Recommendations Pediatric Health Care served as guideline determining measures. Quality related well child visits, developmental screenings,...