- Spatial Neglect and Hemispheric Dysfunction
- Neurobiology of Language and Bilingualism
- Hemispheric Asymmetry in Neuroscience
- Motor Control and Adaptation
- Action Observation and Synchronization
- Musculoskeletal pain and rehabilitation
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Neural and Behavioral Psychology Studies
- Dementia and Cognitive Impairment Research
- Visual perception and processing mechanisms
- Transcranial Magnetic Stimulation Studies
- Spatial Cognition and Navigation
- Reading and Literacy Development
- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- Memory and Neural Mechanisms
- Genetic Neurodegenerative Diseases
- Language Development and Disorders
- Neuroscience, Education and Cognitive Function
- Creativity in Education and Neuroscience
- Neurology and Historical Studies
- Migraine and Headache Studies
- Alzheimer's disease research and treatments
- Functional Brain Connectivity Studies
University of Florida
2015-2024
Florida College
2014-2023
Malcom Randall VA Medical Center
2014-2023
Geriatric Research Education and Clinical Center
2009-2023
North Florida/South Georgia Veterans Health System
2010-2022
Rehabilitation Research and Development Service
2004-2019
John Wiley & Sons (United States)
2018-2019
Hudson Institute
2018-2019
Genomics (United Kingdom)
2019
University of Florida Health
2002-2018
Background The authors designed a prospective longitudinal study to investigate the hypothesis that advancing age is risk factor for postoperative cognitive dysfunction (POCD) after major noncardiac surgery and impact of POCD on mortality in first year surgery. Methods One thousand sixty-four patients aged 18 yr or older completed neuropsychological tests before surgery, at hospital discharge, 3 months Patients were categorized as young (18-39 yr), middle-aged (40-59 elderly (60 older). At 1...
Because hemiinattention is most commonly caused by right parietal lesions, it possible that the left hemisphere attends to contralateral stimuli whereas both and ipsilateral stimuli. We gave lateralized visual 12 normal subjects recorded electroencephalograms. Desynchronization was determined comparing alpha power 1 second before after a stimulus. Although lobe desynchronized right-sided stimuli, equally or These findings support hypothesis dominant for attention.
Abstract If patients with left‐sided hemispatial neglect bisect lines incorrectly because hemianopia or sensory hemiinattention prevents them from seeing how far the line extends to left, a strategy that ensures their left side of in normal field should improve performance. have hypokinesia, moving toward half body space Six right hemisphere infarctions were required identify letter at either end before bisecting line. The task was given placed right, center, midline. Performance trials when...
Alzheimer disease (AD) is the most common dementing illness in elderly, but there equivocal evidence regarding frequency of other disorders such as Lewy body (LBD), vascular dementia (VaD), frontotemporal (FTD), and hippocampal sclerosis (HS). This ambiguity may be related to factors age gender subjects with dementia. Therefore, objective this study was calculate relative frequencies AD, LBD, VaD, FTD, HS among 382 from State Florida Brain Bank effect on these frequencies. AD frequent...
Destruction of parietal areas containing visuokinesthetic motor engrams, where acts may be programmed, should distinguishable from apraxia induced by disconnection these frontal areas. result in inability to distinguish well-performed poorly performed movements, whereas not. We gave movement and act-discrimination tasks apraxic nonapraxic patients with anterior lesions or nonfluent aphasia, posterior fluent aphasia. On both tasks, the performance posterior/fluent was worse than that all...
Abstract This paper is devoted to the development of a composite model limb praxis processing that supported by series dissociations noted in performance apraxic patients. These include die separability production from reception, selectivity input modalities, an "assembled" route imitation, and possible fragmentation semantics into action nonaction system.
Hughlings Jackson noted that, although some aphasic patients were unable to use propositional speech, affective speech appeared be spared. The purpose of this experiment was study with unilateral hemispheric disease in order ascertain if there are asymmetries the comprehension speech. Six subjects had right temporoparietal lesions (left neglect) and six left (fluent aphasias). These presented 32 tape recorded sentences. In 16 trials asked judge emotional mood speaker (happy, sad, angry,...
A 39-year-old man developed retrograde and anterograde amnesia following haemorrhage from an arteriovenous malformation situated near the splenium of corpus callosum. MRI studies demonstrated damage to splenium, a region containing retrosplenial cortex cingulate bundle. The fornix was anterior inferior site maximal damage, but may have been involved; stria terminalis probably spared. Structures known be important in memory spared by lesion included hippocampus, thalamus, basal forebrain....
American Academy of Neurology Dedicated to advancing the art and science neurology, thereby promoting best possible care for patients with neurological disorders A Celebration First 50 Years Neurology 1972;22:660-664 █ My hypothesis is that frontal lobes are seat coordination fusion incoming outgoing products several sensory motor areas cortex. Bianchi (1895)1 made this after excising in animals observing rotary movements side lesion a visual disturbance appeared as contralateral...
Physiologic theories of emotion suggest that activation is important in the experience emotion; patients exhibiting "neglect" as a consequence right parietotemporal dysfunction show flattened affect. We studied arousal with lesions hemisphere who also exhibited emotional indifference, aphasic left hemisphere, and non-brain-damaged controls, by stimulating forearm ipsilateral to side brain lesion while recording galvanic skin responses (GSRs) from fingers on same side. The group neglect had...
Patients with right parietal disease have disturbed comprehension of affective speech. Ability to discriminate speech (make same/different discriminations) and ability repeat emotionally bland sentences tones were tested in three groups subjects—patients dysfunction neglect, conduction aphasics left hemispheric lesions, patients without intracranial disease. performed significantly poorer than did aphasic controls on both a recognition discrimination task. also scored the evocative task...
Previous research has established that patients with right hemisphere damage (RHD) are impaired in the comprehension of emotional prosody and facial expression. There several explanations for this impairment. It may reflect defective acoustic visuospatial analysis, disruption nonverbal communicative representations, or a disturbance meaning. In order to examine these hypotheses, we asked RHD patients, left damaged (LHD) normal controls (NC) judge content sentences describing expressions,...
Patients with hemispatial neglect perform activities poorly in the hemispace contralateral to lesion. We postulate that induced by right hemisphere lesions may be associated a directional hypokinesia: initiation of movements toward lesion is affected more than tested 6 patients caused damage, 7 left damage and no neglect, 12 controls. initiated responses slowly hemispace.
Theoretical models of praxis have two major components, a conceptual system that includes knowledge tool use and mechanical production the information needed to program skilled motor acts. Because patients with Alzheimer's disease may an impairment central system, we wanted learn if they had apraxia by testing their type actions associated use, ability associate tools objects receive action, understand nature problems advantages afford. We studied 32 subjects probable controls examining...