- Management of metastatic bone disease
- Dental Radiography and Imaging
- Medical Imaging and Analysis
- Medical Imaging Techniques and Applications
- Hip disorders and treatments
- Bone health and treatments
- Radiomics and Machine Learning in Medical Imaging
- Adrenal and Paraganglionic Tumors
- Facial Trauma and Fracture Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopaedic implants and arthroplasty
- Orthodontics and Dentofacial Orthopedics
- Head and Neck Surgical Oncology
- Scoliosis diagnosis and treatment
- Amoebic Infections and Treatments
- Lung Cancer Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Craniofacial Disorders and Treatments
- Hip and Femur Fractures
- Phonocardiography and Auscultation Techniques
- Spinal Fractures and Fixation Techniques
- Neuroblastoma Research and Treatments
- Gut microbiota and health
- Ultrasound in Clinical Applications
- Medical Imaging and Pathology Studies
University of Oxford
2025
University of Toronto
2020-2023
Sunnybrook Research Institute
2020-2023
Sunnybrook Hospital
2020-2023
Hôpital Jeanne d'Arc
1997
Introduction Artificial intelligence (AI) models have shown reasonable ability in identifying developmental dysplasia of the hip. This study evaluates impact AI-assisted image interpretation on diagnostic performance ‘expert’ and ‘non-expert’ clinicians. Methods A multi-reader, multi-case was conducted with 10 readers (5 consultants 5 registrars). The included 70 static 2D hip ultrasound scans from patients (age range 0.86-19.86 weeks, mean age 8.6 55.7% female 65.7% left). There were 35...
Fractures remain a huge burden and their management adversely affects individuals' function productivity during the lengthy healing period. Gut microbiota exerts systemic influence on diverse aspects of host physiology, including bone. The primary objective this study was to evaluate if oral probiotic treatment before or after fracture in mouse model could increase cytokines biomarkers essential for bone with subsequent improvement biomechanical properties healed callus.Femoral osteotomy...
Reconstructing facial deformities is often challenging due to the complex 3-dimensional (3D) anatomy of craniomaxillofacial skeleton and overlying soft tissue structures. Bilateral injuries cannot benefit from mirroring techniques as such preinjury information (eg, 2D pictures or 3D imaging) may be utilized determine estimate desired face shape. When patient-specific not available, other options statistical shape models employed; however, these require registration a consistent orientation...
8574 Background: Radiomics has shown promise to non-invasively phenotype disease and address the limitations of extant biomarkers (e.g. PD for immune checkpoint inhibitors (ICI) in cancers, such as NSCLC. However, considerable barriers clinical adoption these tools remain, their dependence on precise annotation tumor extent by experienced users. Here, we demonstrate a radiomic solution that requires only single user mouse click within one or more target lesions baseline CT scan, contour...
Skeletal metastasis can be visualised as changes in bone texture. This investigation aimed to develop an automated method segment spinal osteoblastic metastases μCT images using radiomic-based feature extraction. Ex vivo were acquired of rat lumbar vertebrae with metastases. Pyradiomics was used calculate 3D features for voxels trabecular isolated atlas and level-set based approach. A Random Forest Classifier combine predictions segmenting the lesions. The approach (77 ± 10%) yielded a dice...