A5061002569- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
- RNA Interference and Gene Delivery
- Dermatology and Skin Diseases
- Drug Transport and Resistance Mechanisms
- Graphene and Nanomaterials Applications
- Estrogen and related hormone effects
- Mangiferin and Mango Extracts
- Protein purification and stability
- Lipid Membrane Structure and Behavior
- Carbon Nanotubes in Composites
- Synthesis and biological activity
- Fullerene Chemistry and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Nanoplatforms for cancer theranostics
- Crystallization and Solubility Studies
- Pharmacological Effects of Natural Compounds
- Pharmaceutical studies and practices
- Natural Antidiabetic Agents Studies
Panjab University
2015-2024
Dayanand Medical College & Hospital
2024
Penn State Milton S. Hershey Medical Center
2024
Queens Hospital Center
2024
Icahn School of Medicine at Mount Sinai
2024
Mount Sinai Queens
2024
University College of Medical Sciences
2024
Chitkara University
2005-2024
Government Medical College, Amritsar
2024
Chandigarh University
2015-2023
Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been extensively sought-after owing to their superior portability, loading, stability and patient compliance. The current studies, therefore, entail systematic development, optimization evaluation (in vitro, in situ vivo) of the formulations (SNEDDS) lovastatin employing rational quality by design (QbD)-based approach formulation (FbD). patient-centric target product profile (QTPP) critical attributes (CQAs) were...
The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations methoxsalen enhanced topical delivery effective treatment against vitiligo. ethosomes were prepared by central composite design (CCD) characterized various quality attributes like vesicle shape, size, zeta potential, lamellarity, drug entrapment leaching. optimized subsequently incorporated int Carbopol® 934 gel content, rheological behavior, texture profile, in vitro release, ex...
Topical delivery of local anesthetics has been an area interest for researchers considering the barrier properties skin and unfavorable physicochemical drugs. In present study, efforts have made to modify in vivo efficacy eutectic mixture lidocaine prilocaine by exploiting phospholipid modified microemulsion based systems. The strategic QbD (D-optimal design) enabled systematic optimization approach, after having obtained isotropic ternary phase diagram, resulted into system with most...
The current studies entail Quality by Design (QbD)-enabled development of a simple, rapid, sensitive and cost-effective high-performance liquid chromatographic method for estimation tamoxifen citrate (TMx). factor screening were performed using 7-factor 8-run Taguchi design. Systematic optimization was employing Box-Behnken design selecting the mobile phase ratio, buffer pH oven temperature as critical parameters (CMPs) identified from studies, thus evaluating analytical attributes (CAAs),...
Buccoadhesives have long been employed to improve the bioavailability of drugs undergoing significant hepatic first-pass metabolism. Diltiazem hydrochloride (DLZ) is also reported low oral due an extensive effect. Controlled-release buccoadhesive hydrophilic matrices containing DLZ were prepared using a 32 factorial design. Amounts Carbopol® 934P (CP) and Methocel® K100LV (HPMC) taken as formulation variables (factors) for optimizing bioadhesion, kinetics dissolution diffusion. A...
Carvedilol, a widely prescribed cardiovascular drug for hypertension and congestive heart failure, exhibits low variable bioavailability owing to poor absorption extensive hepatic first-pass metabolism. The current research work, therefore, entails formulation development of liquid self-nano-emulsifying delivery systems (SNEDDS) enhance the carvedilol by facilitating its transport via lymphatic circulation. constituents, i.e. lipids, surfactants, co-surfactants, were selected on basis...