About
Contact & Profiles
A5085630051
Research Areas
- Immune Response and Inflammation
- Asthma and respiratory diseases
- Respiratory viral infections research
- Adrenal Hormones and Disorders
- Neonatal Respiratory Health Research
The University of Melbourne
2015-2017
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly associated with respiratory syncytial virus (RSV), rhinovirus (RV) influenza A (IAV) infection. The ensuing airway inflammation is resistant to the anti-inflammatory actions of glucocorticoids (GCs). Viral infection elicits transforming growth factor-β (TGF-β) activity, a factor we have previously shown impair GC action in human epithelial cells through activation activin-like kinase 5 (ALK5), type 1 receptor...
10.1371/journal.ppat.1006138
article
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PLoS Pathogens
2017-01-03
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