A5000363660- Ginger and Zingiberaceae research
- COVID-19 Clinical Research Studies
- RNA Interference and Gene Delivery
- CAR-T cell therapy research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Seaweed-derived Bioactive Compounds
- Cell death mechanisms and regulation
- Mesenchymal stem cell research
- Nanoparticles: synthesis and applications
- Hepatitis C virus research
- Advancements in Transdermal Drug Delivery
- Curcumin's Biomedical Applications
- SARS-CoV-2 and COVID-19 Research
- Natural product bioactivities and synthesis
- Virus-based gene therapy research
- Bioactive Compounds and Antitumor Agents
- Pharmacological Effects of Medicinal Plants
- Essential Oils and Antimicrobial Activity
- Long-Term Effects of COVID-19
- Immune Cell Function and Interaction
- COVID-19 diagnosis using AI
- Pharmacological Effects of Natural Compounds
- Cancer, Lipids, and Metabolism
- Drug-Induced Hepatotoxicity and Protection
Komar University of Science and Technology
2016-2025
University of Sulaimani
2015-2025
Islamic University
2024
Universiti Putra Malaysia
2013-2020
Kurdistan Regional Government
2016-2020
Uppsala University
2020
National Cancer Council Malaysia
2013-2017
Bioscience (China)
2015
University of Veterinary Medicine
2014
Magnetic iron oxide nanoparticles (Fe3O4 MNPs) are among the most useful metal for multiple applications across a broad spectrum in biomedical field, including diagnosis and treatment of cancer. In previous work, we synthesized characterized Fe3O4 MNPs using simple, rapid, safe, efficient, one-step green method involving reduction ferric chloride solution brown seaweed (Sargassum muticum) aqueous extract containing hydroxyl, carboxyl, amino functional groups mainly relevant to...
Abstract: Zerumbone, a natural dietary lipophilic compound with low water solubility (1.296 mg/L at 25°C) was used in this investigation. The zerumbone loaded into nanostructured lipid carriers using hot, high-pressure homogenization technique. physicochemical properties of the zerumbone-loaded (ZER-NLC) were determined. ZER-NLC particles had an average size 52.68 ± 0.1 nm and polydispersity index 0.29 0.004 µm. Transmission electron microscopy showed that spherical shape. zeta potential...
In the present study, we evaluated effect of brown seaweeds Sargassum muticum methanolic extract (SMME), against MCF-7 and MDA-MB-231 breast cancer cell lines proliferation. This algae was also for reducing activity total polyphenol content. The MTT assay results indicated that extracts were cytotoxic in a dose-dependent manner, with IC 50 22 μ g/ml 55 lines. percentages apoptotic MCF-7-treated cells increased from 13% to 67% by increasing concentration SMME. antiproliferative efficacy this...
The aim of this study is to evaluate the in vitro cytotoxic activity and cellular effects previously prepared ZnO-NPs on murine cancer cell lines using brown seaweed ( Sargassum muticum ) aqueous extract. Treated cells with for 72 hours demonstrated various levels cytotoxicity based calculated IC 50 values MTT assay as follows: 21.7 ± 1.3 μ g/mL (4T1), 17.45 1.1 (CRL-1451), 11.75 0.8 (CT-26), 5.6 0.55 (WEHI-3B), respectively. On other hand, treatments showed no toxicity against normal mouse...
Abstract Very recently, we postulated that the incorporation of citral into nanostructured lipid carrier (NLC-Citral) improves solubility and delivery without toxic effects in vivo . Thus, objective this study is to evaluate anti-cancer NLC-Citral MDA MB-231 cells vitro through Annexin V, cell cycle, JC-1 fluorometric assays. Additionally, aimed reducing tumor weight size 4T1 induced murine breast cancer model. Results showed apoptosis G2/M arrest cells. Furthermore, a prominent...
A simple, selective, and sensitive turn-off fluorescent assay for detecting of tetracycline in pharmaceutical dosage form based on inner filter effect (IFE) sensing platform has been described. In this IFE strategy, N-doped carbon dots (CDs) were prepared by one-pot solvothermal synthesis using milk as a precursor directly used fluorophore IFE. The CDs characterized common spectroscopic microscopic techniques. exhibited excitation-wavelength dependent emission with 10% the fluorescence...
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the has been reported to possess good therapeutic features including antiproliferative anticancer modalities. The self nano-emulsifying drug delivery system (SNEDDS) a type of liquid-lipid nanocarrier that suitable for loading insolubilized oil-based such as Citral. This study reports design optimization SNEDDS formulation, synthesis characterization...
Abstract: Among nanoparticles used for medical applications, palladium (PdNPs) are among the least investigated. This study was undertaken to develop PdNPs by green synthesis using white tea (W.tea; Camellia sinensis ) extract produce [email protected] NPs. The NPs were characterized UV–vis spectroscopy and X-ray diffractometry, evaluated with transmission electron microscopy (TEM) scanning (SEM). spherical (size 6–18 nm) contained phenols flavonoids acquired from W.tea extract. has good...
Abstract: This investigation evaluated the antileukemia properties of a zerumbone (ZER)-loaded nanostructured lipid carrier (NLC) prepared by hot high-pressure homogenization techniques in an acute human lymphoblastic leukemia (Jurkat) cell line vitro. The apoptogenic effect ZER-NLC on Jurkat cells was determined fluorescent and electron microscopy, Annexin V-fluorescein isothiocyanate, Tdt-mediated dUTP nick-end labeling assay, cycle analysis, caspase activity. An MTT...
This study was aimed to investigate the structure of bioactive components black seed oil (BSO) and their antimicrobial cytotoxic effects. Initially, structural examination conducted using various spectroscopic techniques, such as FTIR, TLC, UV-visible spectroscopy, which are important in determining substituents, functional groups, presence conjugated double bonds BSO. From FTIR spectra, a variety sharp, strong, weak peaks were specified relating main thymoquinone (TQ), dithymoquinone,...
Abstract: The study describes an in situ green biosynthesis of zinc oxide nanocomposite using the seaweed Sargassum muticum water extract and hyaluronan biopolymer. morphology optical properties hyaluronan/zinc (HA/ZnO) were determined by Fourier transform infrared spectroscopy, X-ray diffraction, field emission scanning electron microscopy, transmission ultraviolet–vis analysis. Electron microscopy diffraction analysis showed that nanoparticles polydispersed with a mean size 10.2±1.5 nm....