- Animal Nutrition and Physiology
- Chemical Synthesis and Analysis
- Meat and Animal Product Quality
- Cell Image Analysis Techniques
- Rabbits: Nutrition, Reproduction, Health
- Venomous Animal Envenomation and Studies
- DNA and Nucleic Acid Chemistry
- Viral Infectious Diseases and Gene Expression in Insects
- Pharmacological Effects and Assays
- Synthetic Organic Chemistry Methods
- Electron Spin Resonance Studies
- X-ray Diffraction in Crystallography
- Biochemical and Structural Characterization
- Crystallization and Solubility Studies
- Antimicrobial Peptides and Activities
- Acute Myocardial Infarction Research
- Phytochemicals and Antioxidant Activities
- Diabetes Treatment and Management
- Nuts composition and effects
- Organometallic Complex Synthesis and Catalysis
- Lanthanide and Transition Metal Complexes
- Viral gastroenteritis research and epidemiology
- RNA Interference and Gene Delivery
- Click Chemistry and Applications
- Animal health and immunology
University of Ioannina
2021-2024
Laboratoire de Chimie Physique
2016
Université de Lorraine
2016
Naturally occurring antibodies (NAbs), which are major components of innate immunity, exist in circulation under healthy conditions without prior antigenic stimulation and able to recognize both self- non-self-constituents. The present study aimed at identifying potential immunological differences between commercial fast- slow-growth broilers (n = 555) raised conventional free-range systems, respectively, through the use specificity, isotypes levels circulating NAbs. possible beneficial...
The global demand for improvement in the welfare conditions of broilers has generated necessity to implement alternative rearing systems as well less intensive growth hybrids. majority data on farming methods, notwithstanding their abundance, are result small-scale experiments. present extended field study examined effect two different industrial broilers’ antioxidant status, performance, and meat quality, including 13 replicates each breeding system (intensive conventional; free range)...
The generation of cell-penetrating peptides as cargo-delivery systems has produced an immense number studies owing to the importance these tools deliver molecules into cells, well due interest shed light a yet unclear mechanism entrance cells. However, many might present drawbacks causing cellular toxicity, or being entrapped in endosomes, result their degradation before they meet target. In this work, cargo transporting molecule, Cell Penetrating Sequential Oligopeptide Carrier (CPSOC),...
Olive oil contains a variety of antioxidants, including vitamin E. Its consumption protects against oxidative stress, which is involved in many pathological conditions, affecting animals’ development and their general welfare. The present study aimed to investigate the effect olive paste flour (OPF) on antioxidant status performance broiler chickens raised field conditions. Total 18.000 broilers was randomly allocated equal numbers two poultry houses. were grouped according diet as follows:...
Tyrosine radicals are notoriously short-lived/unstable in solution, while they present an impressive degree of stability and versatility bioenzymes. Herein, we have developed a library hybrid biomimetic materials (HBMs), which consists tyrosine-containing oligopeptides covalently grafted on SiO2 nanoparticles, studied the formation, lifetime, redox properties tyrosyl radicals. Using electron paramagnetic resonance spectroscopy, radical-spin distribution as probe local microenvironment HBMs....
Chemoselective reactions have played a crucial role in the development of high-molecular-weight (>3000 Da) macromolecules with branched architecture, particularly as peptides and epitope-based vaccines emerged promising tools for drug development. Based on this, this study, we designed synthesized peptide macromolecule CH3CO-[K-Aib-C(3,9-CH2NHCOCH3; 6,12-DFLC(CH2NHCOCH3)KKESEK)]4-NH2 [Ac-K-Aib-C(3,9-Acm); 6,12-epitope)]4-NH2] using chemoselective thioether bond formation between carrier...
Advances in synthetic peptide methodologies have enabled the development of macromolecules mimicking protein properties and found applications various fields, particularly immunology. Furthermore, Sequential Oligopeptide Carriers (SOCn CPSOC) been designed as multi-functional core molecules, to which multiple bio-cargos can be anchored, allowing construction high molecular weight molecules (>3000 Da) capable inducing a strong immune response. This study presents design synthesis...
Identifying blood components influenced by rearing systems that serve as biomarkers to distinguish free-range from conventional broilers can improve animal health, welfare, and productivity. The current study aimed evaluate specific parameters related immune function tissue stress, differentiate free-range, slow-growing Sasso conventionally raised fast-growing Ross 308 broilers. For this purpose, serum IgM Natural Antibodies (NAbs) targeting actin lipopolysaccharides (LPS) key immunological...
This study investigated the influence of dietary supplementation with oregano oil premix on antioxidant status, performance, and meat quality slow-growth genotype chickens raised under a commercial production system. The included two groups, nine replicates: Group A) 54.000 broilers in free-range farms fed basal diet, B) 27.000 diet supplemented premix. Oregano was blended standard (120 g/ton), which then mixed feed (amount adjusted growth stage). results showed that serum total capacity...