Bruno Piedbœuf
A5012462205- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Infant Nutrition and Health
- Neonatal and fetal brain pathology
- Respiratory Support and Mechanisms
- Birth, Development, and Health
- Tracheal and airway disorders
- Child and Adolescent Health
- Emergency and Acute Care Studies
- Congenital Heart Disease Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Cell Adhesion Molecules Research
- Neonatal and Maternal Infections
- Fatty Acid Research and Health
- Preterm Birth and Chorioamnionitis
- Hospital Admissions and Outcomes
- Pleural and Pulmonary Diseases
- Cardiovascular Conditions and Treatments
- Effects of Radiation Exposure
- Trauma and Emergency Care Studies
- Clinical Nutrition and Gastroenterology
Université Laval
2016-2025
Wilfrid Laurier University
2000-2025
Centre hospitalier universitaire de Québec
2008-2022
Montreal Children's Hospital
1997-2020
Dalhousie University
2020
Izaak Walton Killam Health Centre
2020
University of Toronto
2020
McGill University Health Centre
2020
Infant
2020
3M (United States)
2020
KEY POINTS Congenital diaphragmatic hernia (CDH), which occurs in about 1 3300 live births, is a congenital defect the diaphragm that allows herniation of abdominal viscera into thorax.[1][1] The resulting abnormal lung development leads to pulmonary hypoplasia and hypertension,
<h3>Importance</h3> Neonatal hypothermia has been associated with higher mortality and morbidity; therefore, thermal control following delivery is an essential part of neonatal care. Identifying the ideal body temperature in preterm neonates first few hours life may be helpful to reduce risk for adverse outcomes. <h3>Objectives</h3> To examine association between admission outcomes estimate lowest rates infants born at fewer than 33 weeks' gestation. <h3>Design, Setting, Participants</h3>...
<h3>BACKGROUND:</h3> Preterm birth is the leading cause of morbidity and mortality in children younger than 5 years. We report changes neonatal outcomes care practices among very preterm infants Canada over 14 years within a national, collaborative, continuous quality-improvement program. <h3>METHODS:</h3> retrospectively studied born at 23–32 weeks' gestation who were admitted to tertiary intensive units that participated Evidence-based Practice for Improving Quality program Canadian...
We investigated the effect of gender on survival and short-term outcomes extremely premature infants (≤27 weeks) born in Canada. The records admitted between 2000 2005 to a neonatal intensive care unit participating Canadian Neonatal Network were reviewed for infant gender, birth weight, gestational age, outborn status, Score Acute Physiology II, antenatal corticosteroid exposure. following recorded: at final discharge, necrotizing enterocolitis, bronchopulmonary dysplasia (BPD),...
<h3>Importance</h3> Maternal docosahexaenoic acid (DHA) supplementation may prevent bronchopulmonary dysplasia, but evidence remains inconclusive. <h3>Objective</h3> To determine whether maternal DHA during the neonatal period improves dysplasia–free survival in breastfed infants born before 29 weeks of gestation. <h3>Design, Setting, and Participants</h3> Superiority, placebo-controlled randomized clinical trial at 16 Canadian intensive care units (June 2015-April 2018 with last infant...
Acquired brain injury remains common in very preterm infants and is associated with significant risks for short- long-term morbidities. Cranial ultrasound has been widely adopted as the first-line neuroimaging modality to study neonatal brain. It can reliably detect clinically abnormalities that include germinal matrix intraventricular hemorrhage, periventricular hemorrhagic infarction, post-hemorrhagic ventricular dilatation, cerebellar white matter injury. The purpose of this article...
Fibrosis, characterized by the accumulation of collagen, is a late result thoracic irradiation. The purpose this study was to determine if extracellular matrix protein and transforming growth factor beta mRNA expression are altered in course pulmonary fibrosis after irradiation, then these changes differ between two strains mice which vary their sensitivity radiation. Radiation-sensitive (C57BL/6) radiation-resistant (C3H/HeJ) were irradiated with single dose 5 or 12.5 Gy thorax. Total lung...
Background:Minimally invasive surfactant therapy (MIST) is a new strategy to avoid mechanical ventilation (MV) in respiratory distress syndrome. The primary aim of this study was test MIST as means avoiding MV exposure and pneumothorax occurrence moderate late preterm infants (32 36 weeks’ gestational age).
Background Very preterm infants are at high risk of death or severe morbidity. The objective was to determine the significance congenital heart defects (CHDs) for these risks. Methods and Results This cohort study included from 10 countries born 2007-2015 24 31 weeks' gestation with birth weights <1500 g. Severe CHDs were defined by International Classification Diseases, Ninth Revision (ICD-9) Tenth (ICD-10) codes categorized as those compromising systemic output, causing sustained cyanosis,...
<h3>Background:</h3> Preterm birth (birth before 37 wk of gestation) occurs in about 8% pregnancies Canada and is associated with high mortality morbidity rates that substantially affect infants, their families the health care system. Our overall goal to create a transdisciplinary platform, Canadian Birth Network (CPTBN), where investigators, stakeholders will work together improve childhood outcomes preterm neonates. <h3>Methods:</h3> national cohort include 24 maternal-fetal/obstetrical...
Late-onset sepsis in very low birth weight (VLBW) infants is a diagnostic challenge. We aimed to evaluate the utility of C-Reactive protein (CRP) and complete blood count (CBC) for late-onset VLBW infants. In 5-year retrospective cohort 416 born at less than 1500 g, there were 590 separate evaluations. CRP CBC drawn time initial culture (T0), 16–24 h (T24) 40–48 (T48) after. The positive cut-off values abnormal following: ≥10 mg/L with least one anomaly, including white cell < 5000/mm3,...
OBJECTIVES To determine whether maternal supplementation with high-dose docosahexaenoic acid (DHA) in breastfed, very preterm neonates improves neurodevelopmental outcomes at 18 to 22 months’ corrected age (CA). METHODS Planned follow-up of a randomized, double-blind, placebo-controlled, multicenter trial compare born before 29 weeks’ gestational (GA). Lactating mothers were randomized receive either DHA-rich algae oil or placebo within 72 hours delivery until 36 postmenstrual age....