- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Shoulder and Clavicle Injuries
- Retinal Development and Disorders
- Shoulder Injury and Treatment
- Ocular Infections and Treatments
- Cardiovascular Health and Risk Factors
- Axon Guidance and Neuronal Signaling
- Ocular Oncology and Treatments
- Acute Ischemic Stroke Management
- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Ophthalmology and Visual Impairment Studies
- Neurological Disorders and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrhythmias and Treatments
Nagoya City University
2013-2022
Mizuho (Japan)
2017
Centre Hospitalier privé Saint Grégoire
2015
Hokusho University
2011
Gifu Pharmaceutical University
1997
To evaluate the area of foveal avascular zone (FAZ) detected by en face OCTA (AngioVue, Avanti OCT; Optovue) in healthy and diabetic eyes.Retrospective chart review patients who underwent fundus examination including OCTA. Eyes with proliferative retinopathy history laser photocoagulation were excluded. The FAZ superficial deep plexus layers measured evaluated using ImageJ software.The layer was 0.25 ± 0.06 mm² eyes (n = 19), whereas it 0.37 0.07 without 24) 0.38 0.11 20). Diabetic showed...
To study the association between distributions of microaneurysms detected by en face optical coherence tomography angiography (OCTA) and diabetic macular edema (DME).The design was a retrospective chart review 27 patients (33 eyes) with DME. The eyes were scanned using OCTA (6 × 6 mm) spectral-domain (SD) OCT cube. Each images capillary plexus overlaid onto image topographic map, densities measured ImageJ software. distribution evaluated.For in areas without edema, 77.3 ± 8.1% these located...
Purpose: This study evaluates the retinal hemodynamics using optical coherence tomography angiography (OCTA) before and after anti–vascular endothelial growth factor (VEGF) therapy in patients with macular edema associated vein occlusion (RVO). Methods: Twelve (23 eyes; mean age, 64 years) were included (eight eyes branch RVO, four central 11 unaffected fellow eyes. The best-corrected visual acuity (BCVA) thickness (CRT) measured 6 months treatment. foveal avascular zone (FAZ), nonperfused...
The purpose of this study was to compare the angiographic findings polypoidal choroidal vasculopathy (PCV) detected by indocyanine green angiography (ICGA) and en face optical coherence tomography (OCTA).The design a retrospective chart review 20 eyes with clinical diagnosis treatment-naive PCV, seen at Nagoya City University Hospital between December 2014 January 2016. Indocyanine performed Heidelberg Retina Angiography 2 OCTA using Avanti RTVue XR.Twenty patients (18 male, female) were...
Abstract Intravitreal anti-vascular endothelial growth factor (VEGF) agents can treat macular edema (ME) in branch retinal vein occlusion (BRVO). However, refractory ME, the mechanism of which is not well elucidated, occurs frequently. Sixty-six eyes with ME secondary to BRVO were enrolled this retrospective observational case-control study. Twenty received a sub-Tenon’s capsule injection triamcinolone acetonide (STTA), 22 an intravitreal anti-VEGF (ranibizumab), 16 switched from STTA...
Aims To detect collateral vessels using optical coherence tomography angiography (OCTA) in eyes with branch retinal vein occlusion (BRVO) and to investigate the associations visual outcomes macular oedema. Methods Eyes oedema secondary BRVO that underwent OCTA at baseline were followed up for more than 6 months enrolled. The presence of collaterals, whether collaterals leaky or not, investigated. Results Twenty-eight 28 patients (8 men 20 women; mean age, 68 years) Collaterals detected 23...
<b><i>Purpose:</i></b> To evaluate the usefulness of indocyanine green angiography (ICGA) to detect leaking spots and effectiveness ICGA-guided focal laser photocoagulation in eyes with diabetic macular edema (DME). <b><i>Methods:</i></b> Ten (8 patients) diffuse DME diagnosed using fluorescein (FA) refractory a sub-Tenon injection triamcinolone acetonide (STTA), grid photocoagulation, or both were enrolled. FA ICGA performed Heidelberg Retina...
To see if cultured human retinal pigment epithelial (RPE) cells have the capacity to synthesize neurotrophins, including nerve growth factor (NGF), brain-derived (BDNF), and neurotrophin-3 (NT-3).Expression of mRNAs for neurotrophins was studied by reverse transcription polymerase chain reaction (PCR) method. Quantitative analysis gene expression done using a semiquantitative PCR Secretion NGF-like immunoreactivity (NGF-LI) into culture medium analyzed enzyme immunoassay (EIA).Cultured RPE...
To evaluate navigated laser photocoagulation for the treatment of refractory diabetic macular edema (DME). Retrospective study 25 eyes (21 patients) treated with Navilas 577+ focal system. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (OCT) parameters were measured at baseline, 1, 3, 6 months, final visit. The mean follow-up period was 12.8 ± 2.4 (7-16 months). All subjects had history previous which injection triamcinolone acetonide or antivascular...
<b><i>Purpose:</i></b> To study the structural and functional changes of retinal ischemia investigate their association with macular edema (ME) or microaneurysm (MA) formation in eyes vein occlusion (RVO). <b><i>Methods:</i></b> Sixty 30 patients (27 branch [b]RVO, 3 central RVO, fellow eyes) were retrospectively reviewed. Optical coherence tomography (OCT), OCT angiography (OCTA), microperimetry performed simultaneously to measure thickness...
The purpose of this study is to report wide-field angiography findings before and after steroid therapy in a case with bilateral Vogt-Koyanagi-Harada (VKH) disease. A 44-year-old woman presented blurred vision metamorphopsia accompanied by symptoms headache tinnitus. baseline best-corrected visual acuity was 20/20 both eyes. Ophthalmic examination revealed shallow anterior chamber panuveitis multiple serous retinal detachments eyes ciliochoroidal the left eye. Wide-field fluorescein...
To evaluate the location of microvascular abnormalities using wide-field fluorescein angiography (WFFA) and investigate impact on visual outcome in eyes with branch retinal vein occlusion (BRVO).Forty 39 patients (24 males 15 females an average age 71 years) were retrospectively reviewed. One patient had BRVO bilaterally. WFFA was performed all to perfusion status detect abnormalities. The images divided into 3 zones: zone 1, posterior pole; 2, mid-periphery; 3, far periphery, order document...
We aimed to evaluate the prevalence of abnormal peripheral fundus autofluorescence (FAF) in wet age-related macular degeneration (AMD) using wide-field imaging instrument.A retrospective, case-controlled study involving 66 eyes 46 Japanese AMD patients and 32 20 control was performed. Wide-field FAF images were obtained for typical (37 eyes/28 patients), polypoidal choroidal vasculopathy (PCV) (22 eyes/20 retinal angiomatous proliferation (RAP) (seven eyes/four patients). Two masked...
Purpose: To report 24-month results after one intravitreal ranibizumab (IVR) injection followed by pro re nata (PRN) dosing for macular edema (ME) branch retinal vein occlusion (BRVO).Methods: Eyes with BRVO met the followings were included: 77 letters or less best-corrected visual acuity (BCVA) (Early Treatment Diabetic Retinopathy Study [ETDRS] score) and central thickness (CRT) of 250 µm more. IVR was performed a PRN regimen. The retreatment criteria included loss five more ETDRS compared...
The aim of this study is to report the 6-month results after one intravitreal ranibizumab (IVR) injection followed by pro re nata dosing for macular edema (ME) branch retinal vein occlusion.The inclusion criteria included a minimal patient age 18 years, 20 letters or more best-corrected visual acuity (BCVA) (Early Treatment Diabetic Retinopathy Study [ETDRS] score, 77 less), and central thickness (CRT) 250 microns more. primary outcome measure was mean BCVA change from baseline at month 6;...
Purpose: The purpose of this article is to evaluate long-term change the foveal avascular zone (FAZ) area in diabetic eyes using optical coherence tomography angiography (OCTA) (AngioVue, Avanti OCT, Optovue). Methods: A retrospective chart review was conducted patients who had undergone OCTA fundus examinations with at least 12 months follow-up. Eyes previous laser photocoagulation and antivascular endothelial growth factor treatments were excluded. ImageJ software used FAZ superficial...
Purpose: To classify microaneurysms (MAs) and investigate the relationships with retinal edema in eyes branch vein occlusion (BRVO). Study Design: Retrospective, observational, consecutive case series. Methods: Eyes MAs due to BRVO that underwent optical coherence tomography angiography (OCTA) were enrolled. on OCTA images morphologically classified into six types: focal bulge, saccular, fusiform, mixed (saccular/fusiform), pedunculated, irregular. The frequency, size, location, also...