- Acupuncture Treatment Research Studies
- Complementary and Alternative Medicine Studies
- Cancer, Hypoxia, and Metabolism
- Nitric Oxide and Endothelin Effects
- Urinary Bladder and Prostate Research
- Angiogenesis and VEGF in Cancer
- Pelvic floor disorders treatments
- Infant Health and Development
- Tryptophan and brain disorders
- Exercise and Physiological Responses
- Nutritional Studies and Diet
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Clostridium difficile and Clostridium perfringens research
- Dermatology and Skin Diseases
- Psychosomatic Disorders and Their Treatments
- Hepatitis C virus research
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Clinical practice guidelines implementation
- Myofascial pain diagnosis and treatment
- Advanced Neuroimaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Bariatric Surgery and Outcomes
- Colorectal Cancer Treatments and Studies
Taipei Veterans General Hospital
2007-2023
University of Cincinnati Medical Center
2009-2017
Harvard University
2009
University of Cincinnati
2009
National Institutes of Health
1983-2005
St. Elizabeth's Medical Center
1996
Tufts University
1994-1996
National Institute of Diabetes and Digestive and Kidney Diseases
1983
BACKGROUND Hypoxia and indirect angiogenic factors may stimulate angiogenesis via induction of endothelial cell mitogen(s). To evaluate this hypothesis, we investigated whether low oxygen tension or cytokines known to promote neovascularization in vivo could modulate the expression either vascular growth factor (VEGF) basic fibroblast (bFGF) human smooth muscle cells (SMCs). METHODS AND RESULTS SMCs were treated with platelet-derived BB (PDGF-BB) transforming factor-beta 1 (TGF-beta 1)...
Vascular endothelial growth factor (VEGF)/vascular permeability (VPF), an cell (EC)-specific mitogen, stimulates angiogenesis in vivo, particularly ischemic regions. VEGF/VPF expression by cells of hypoxic tissues coincides with its two receptors, KDR and flt-1, ECs the same tissues. We investigated whether hypoxia or hypoxia-dependent conditions operate coordinating this phenomenon. Human umbilical vein microvascular were exposed to direct medium conditioned (CM) myoblasts maintained for 4...
Tobacco smoking is responsible for human diseases of the lung, heart, circulatory system and various kinds cancers, a serious public health problem worldwide. Acupuncture has been promoted as treatment modality cessation. However, its efficacy still remains controversial.We conducted prospective, randomized, controlled trial using auricular acupuncture cessation in 131 adults who wanted to stop smoking. Thirteen subjects withdrew from study 118 were included final analyses (mean age, 53.7...
Complementary therapy with acupuncture for Parkinson's disease (PD) has been studied quite a long time, but the effectiveness of treatment still remains unclear. The aim this study is to evaluate integrated effects in PD patients who received western medicine. In short-term study, 20 twice week acupoints DU 20, GB LI 11, 10, 4, 31, ST 32, 34 and 38 along medicine 18 weeks, controlled only. long-term treatment, 13 36 weeks. outcome parameters include Unified rating scale (UPDRS), Beck Anxiety...
Journal Article Isolation Rate and Toxigenic Potential of Clostridium difficile Isolates from Patients with Cystic Fibrosis Get access T. C. Wu, Wu Microbiology Services, Department Clinical Pathology; Pediatric Metabolism Branch, National Institute Arthritis, Diabetes, Digestive Kidney Disease, Institutes Health, Bethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar V. P. McCarthy, McCarthy J. Gill The Infectious Diseases, Volume 148, Issue 1,...
Purpose: To investigate the required sample size for and feasibility of a full-scale randomized controlled trial examining impact "dose" effect acupuncture in treating sciatica. Patients methods: Fifty-seven patients with sciatica, aged 35–70 years, were recruited screened. Thirty-one participants randomly assigned to receive "low-dose" manual (MAL) (n= 15) or "high-dose" (MAH) (n=16). The treatment was administered twice weekly 4 weeks. primary outcome visual analog scale (VAS) score at...
To investigate the functional connectivity (FC) in nonacute sciatica and neuronal correlation of acupuncture analgesia. A prospective study employing resting-state magnetic resonance imaging was conducted. Twelve patients were enrolled to receive six or 18 acupoints treatment twice a week for 4 weeks. Regional homogeneity (ReHo) seed-based FC performed. analysis demonstrated greater alteration right posterior cingulate cortex (PCC) during pre-acupuncture phase than postacupuncture phase....
Background: Traditional Chinese medicine (TCM) is widely used by ethnic communities. TCM covered Taiwan’s National Health Insurance (NHI) program. We evaluated the efficacy and outcomes of complementary herbal (CHM) therapy in patients with cancer. Methods: This population-based cohort study was conducted using data who received a cancer diagnosis between 2005 2015 Taiwan. Eligible were divided into standard CHM groups. The group further low cumulative dosage (LCD), medium (MCD), high (HCD)...
For decades, professional divisions have been represented as the main structural in Western medicine throughout world. In Taiwan, medical policymakers are also interested designing of traditional Chinese (TCM). Therefore, this study evaluated current status and potentiality TCM Taiwan using data from year 2012 obtained National Health Insurance Research Database; database provides information regarding age gender physicians (TCMPs); total visit counts; contracted institution codes; groupings...
Traditional Chinese medicine (TCM) practitioners assess body constitution (BC) as a treatment basis for maintaining homeostasis. We investigated patterns in spontaneous brain activity different BC groups using resting-state functional magnetic resonance imaging (rsfMRI) and determined the relationship between these quality of life (QOL). Thirty-two healthy individuals divided into two (body questionnaire (BCQ)-gentleness [BCQ-G] BCQ-deficiency [BCQ-D]) based on (BCQ) underwent rsfMRI to...
The current Western medicine treatment options for benign prostatic hyperplasia (BPH) have various degrees of documented effectiveness. However, the uses these interventions are limited to specific patient populations or certain side effects that interfere with quality life. This study evaluated clinical a Chinese herbal (CHM) on patients BPH.This was single-arm pilot study. Twenty BPH were enrolled, and they required take investigated CHM three times day 8 weeks, along their medicine....
Depressive disorders (DD) affect not only mood and behavior but also various physical functions. Traditional Chinese medicine (TCM) has been shown to have some benefits in treating DD. However, one formula or single herb might be show high efficacy when used treat depression. Thus, this study aimed examine the core prescription pattern of herbal (CHM) among patients with DD Taiwan as a reference for related research clinical applications.All patients, who had diagnosed major depressive...
Benign prostatic hyperplasia (BPH) can affect quality of life and cause various complications. Previous studies have suggested that Chinese herbal medicine alleviate symptoms in patients with BPH. This study aimed to investigate whether the prescription VGH-BPH1 BPH when used as an add-on treatment.In this crossover, randomized, double-blind, placebo-controlled trial, were randomly segregated into two groups: group A received VGH-BPH1, B a placebo for 8 weeks. Subsequently, after 2-week...