The murine Ly49 family contains nine genes in two subgroups: the inhibitory receptors (Ly49A, B, C, E, F, G2, and I) noninhibitory (Ly49D H). Unlike their counterparts, Ly49D H do not contain immunoreceptor tyrosine-based motifs but associate with a recently described co-receptor, DAP12, to transmit positive signals natural killer (NK) cells. DAP12 is also expressed myeloid cells, coupled it there are unknown. Here we document signaling pathways of Ly49D/DAP12 complex NK We show that...

Objective This study examined whether the number of emergency department visits for “mental and psychosocial problems” varies with temperature or humidity. Methods The in three geographic areas Québec were as a function humidity by using routinely collected May–September data 1995–2007 (N=347,552 visits). Data two age groups (under 65 older) examined. Incidence rate ratios mean estimated Poisson regression generalized additive models. Results tended to increase increasing temperature. At...

Green spaces (GS) have many functions that can moderate the climate change impact and help prevent disease thus alleviate public health expenses in a context of aging societies. However, several socioeconomic, demographic geographic processes may render access to GS challenging. Moreover, it is often critical know what type service develop at specific place. Also, measurements accuracy issues could be for planning decision making. As an example happen other cities different sizes, we modeled...

This article addresses the issue of communication emotion by actors. In Study 1, facial behavior 6 actors portraying emotions as felt or unfelt were analyzed with Facial Action Coding System. Results indicated that portrayals closer to expression genuine than for 3 under investigation. 2 examined decoding actors' from behavior. Decoders found be very accurate in recognizing emotional category but not judging encoding condition.

In Nunavik, chlorine-treated water is delivered daily, by tank truck, to the houses, where it stored in tanks. A large part of Inuit population continues depend on an untreated supply, however. This traditional activity poses certain risks a region with abundant presence migratory animals. Nunavik has also experienced significant climate warming since beginning last decade. The main goal this study, which took place 2003 and 2004, was evaluate drinking habits that may residents at increased...

Starting from a Hamiltonian description of the photon within set Bargmann-Wigner equations we derive new semiclassical motion for propagating in static gravitational field. These which are obtained representation diagonalizing at order $\ensuremath{\hbar}$, present first corrections to geometrical optics. The shows kind helicity-torsion coupling. However, even torsionless space-time, photons do not follow usual null geodesic as consequence an anomalous velocity term. This term is responsible...

One of the consequences climate change is increased frequency and intensity heat waves which can cause serious health impacts. In Québec, July 2010 was marked by an unprecedented wave in recent history. The purpose this study to estimate certain impacts wave. crude daily death emergency department admission rates during were analyzed relation comparison periods using 95% confidence intervals. During wave, showed a significant increase 33% for deaths 4% admissions periods. No displacement...

Studies have suggested an association between climate variables and circulatory diseases. The short-term effect of conditions on the incidence ischemic heart disease (IHD) over 1989-2006 period was examined for Quebec's 18 health regions. Analyses were carried out two age groups. A GAM statistical model, that blends properties generalized linear models with additive models, used to fit standardized daily hospitalization rates IHD their relationship climatic up weeks prior day admission,...

Abstract Background The impact of climate change and particularly increasing temperature on mortality has been examined for three cities in the province Québec, Canada. Methods Generalized linear Poisson regression fitted to total daily each city. Smooth parametric cubic splines humidity have used do nonlinear modeling these parameters. model, control day week non-temperature seasonal factors, a smooth function time, including delayed effects. model was then assess variation simulated future...

We investigated adults' voluntary control of 20 facial action units theoretically associated with 6 basic emotions (happiness, fear, anger, surprise, sadness, and disgust). Twenty young adults were shown video excerpts asked to reproduce them as accurately possible. Facial Action Coding System (FACS; Ekman & Friesen, 1978a) coding the productions showed that succeeded in activating 18 target actions units, although they often coactivated other units. Voluntary was clearly better for some...

Gold-rich volcanogenic massive sulfide (VMS) deposits consist of synvolcanic banded and concordant lenses adjacent stockwork feeder zones in which gold concentration g/t Au exceeds the combined Cu, Pb, Zn grades wt percent thus constitutes main commodity. The Agnico-Eagle LaRonde Penna deposit is a world-class Au-rich VMS (production, reserves resources 58.8 Mt at 4.31 Au) located eastern part Blake River Group Abitibi greenstone belt. comprises four stacked within upper member Bousquet...

This study aimed at determining the role of proximity to specific types green spaces (GSes) as well their spatial location in relationship with most morbid cardiovascular diseases (CVD) and diabetes. We measured accessibility various GS used a cross-sectional approach census Dissemination Area (DA) levels Montreal Quebec City metropolitan zones for period 2006–2011. Poisson negative binomial regression models were fitted quantify between distances CVD morbidity some risk factors (diabetes...

The Duchenne marker has been proposed as a universal of smile authenticity. However, Elfenbein, Beaupré, Levesque, and Hess (2007 ) found that, whereas Canadians typically show the when posing happiness, Gabonese do not. We therefore investigated whether is perceived authenticity by Mainland Chinese living in Quebec, Canada. results that not use to assess at all. immigrants Quebec showed sensitivity only judging smiles French-Canadian encoders, suggesting learning this cultural dialect...

Heat waves are one of the most common direct impacts anthropogenic climate change and excess mortality their apparent impact. While Turkey has experienced an increase in heat wave episodes between 1971 2016, no epidemiological studies have examined potential on public health so far. In this study Istanbul attributable to extreme 2013 2017 is presented. Total deaths were calculated using rates across different categories, including age, sex, cause death. The analysis shows that three summer...

As the health consequences of climate change (CC) will likely become more manifest in future, family physicians have to be knowledgeable about these impacts and ways which they can affect their patients. The main aim this study was propose a competency framework questionnaire used conduct needs analysis identify prioritize physicians' real educational regarding CC.A mixed method combining qualitative interview quantitative online (n = 24 physicians). assessed key beliefs related...

Abstract Objective Climate change is expected to increase global temperatures. How temperature-related mortality risk will not completely understood, and how future demographic changes affect needs be clarified. We evaluate across Canada until 2099, accounting for age groups scenarios of population growth. Methods used daily counts non-accidental 2000 2015 all 111 health regions Canada, incorporating in the study both urban rural areas. A two-part time series analysis was estimate...

Killer cell inhibitory receptors represent a family of p58/70-Ig-like proteins expressed on the surface human NK cells. Engagement class I MHC by killer turns off lytic machinery This receptor/ligand interaction results in phosphorylation intracellular tyrosine residues p58/70 proteins. Murine cells express an unrelated type II lectin-like proteins, Ly-49, that have similar functions. Ly-49A, -C, and -G2 murine receptors. However, Ly-49D functions as activation receptor dichotomy function...