- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Ocular Infections and Treatments
- Orthopedic Infections and Treatments
- Urinary Tract Infections Management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Corneal Surgery and Treatments
- Polydiacetylene-based materials and applications
- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Bacterial biofilms and quorum sensing
- Bioactive Compounds and Antitumor Agents
- Vibrio bacteria research studies
- Intensive Care Unit Cognitive Disorders
- Bacteriophages and microbial interactions
- Aquaculture disease management and microbiota
King Salman International University
2023-2024
Misr University for Science and Technology
2018-2022
The most prevalent conditions among ocular surgery and COVID-19 patients are fungal eye infections, which may cause inflammation dry eye, morbidity. Amphotericin-B drops commonly used in the treatment of infections. Lactoferrin is an iron-binding glycoprotein with broad-spectrum antimicrobial activity for conjunctivitis, inflammation. However, poor aqueous stability excessive nasolacrimal duct draining impede these agens' efficiency. aim this study was to examine effect Amphotericin-B, as...
Abstract Background Urinary tract infections (UTIs) caused by antibiotic-resistant bacteria have become a significant public health concern. The increasing ineffectiveness of antibiotics has led to renewed focus on investigating other strategies, such as bacteriophages, target specific pathogenic and prevent future resistance. Results This study reports the isolation characterization bacteriophage vB_Eco_ZCEC08 targeting uropathogenic Escherichia coli (UPEC). Phage is morphologically...
The increasing incidence of carbapenem-resistant Klebsiella pneumoniae (CRKP) strains is considered as a terrifying public health concern. This study target was to gain further insight into the virulence traits CRKP isolates in Egypt. carried out by using 43 clinical K. isolates. Antibiotic susceptibility testing, biofilm formation assay, and molecular characterization carbapenemase genes were done for all In addition, genotypic relationship between identified enterobacterial repetitive...
Background: Hypervirulent Klebsiella pneumoniae (hvKp) cause multiple dangerous infections. HvKp can be distinguished from classical K. (cKp) by hyper-mucoviscosity. Presence of genes contribute to hypervirulent phenotype as mucoviscosity-associated gene A (magA) and regulator mucoid (rmpA). Objectives: detect hvKp frequency among strains k.pneumoniae using string test phenotypically, use multiplex polymerase chain reaction for rmpA magA detection. Methodology: Fifty isolates k.pneumoniae,...
Background: Ventilator-associated pneumonia (VAP) is occurring 48-72 hours or later following endotracheal intubation.It characterized by the presence of an infiltrate, whether new progressive, signs systemic infection (fever, leukocytosis), change in sputum, and detection agent.VAP mainly acquired through either major micro aspiration oropharyngeal organisms into distal bronchi, directly via reflux from stomach oropharynx.Objectives: This study aimed to measure VAP rates, identify causative...
Background: Although hepatitis C virus is mainly hepatotropic, it infects peripheral blood mononuclear cells (PBMCs) using them as a reservoir.HCV replication in PBMCs suggested to influence the sustained virological response (SVR) of such patients.Aim work: HCV RNA Detection by real time PCR chronic patients after antiviral therapy compared that serum and if predicting relapse.Methods: Fifty-three genotype 4 infected were selected from hepatology unit, Ain Shams University Hospitals,...
Aim: to evaluate the effectiveness of fosfomycin and Diode laser treatment in experimental osteomyelitis induced by MRSA rabbits. Methods:Osteomylitis Infection was tibiae thirty rabbits injection a bacterial inoculum (7 x 10 6 CFU/ml) clinical isolate two weeks after infection, each animal assigned group: Group ( 1) include animals were left untreated (2); Fosfomycin monotherapy at 75 mg/kg body weight once daily (n_10), 3: (n = 10) treated for 2 with 940 nm .After 2-week period,...
Background: Metallo-beta-lactamase (MβL) mediated resistance is an emergency threat in health care settings, and its identification essential for treatment infection control. Objectives: this study aimed to detect the MβL prevalence Gram negative bacilli (GNB) compare phenotypic detection methods. Methodology: Ninety six (96) isolates of GNB were isolated from different clinical specimens collected patients admitted intensive units (ICU) Ain Shams Hospitals, February 2018 June 2018. Isolates...