A5035888723- Mitochondrial Function and Pathology
- Pharmaceutical Practices and Patient Outcomes
- Migraine and Headache Studies
- Cardiac Ischemia and Reperfusion
- Mesenchymal stem cell research
- Pain Management and Placebo Effect
- Tissue Engineering and Regenerative Medicine
- Cardiac electrophysiology and arrhythmias
- Healthcare Policy and Management
- Nursing Roles and Practices
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Electrospun Nanofibers in Biomedical Applications
- Emergency and Acute Care Studies
- Ion channel regulation and function
- ATP Synthase and ATPases Research
- Health Systems, Economic Evaluations, Quality of Life
- Science, Research, and Medicine
- Congenital heart defects research
- Metabolism and Genetic Disorders
- Psychosomatic Disorders and Their Treatments
- Patient Satisfaction in Healthcare
- Botulinum Toxin and Related Neurological Disorders
- Advanced MRI Techniques and Applications
- Biotechnology and Related Fields
- Nursing Diagnosis and Documentation
Boston Partners in Education
2023
University of Maryland, Baltimore
2009-2014
University of Baltimore
2009-2011
Biotechnology Institute
2009-2010
Mitofusin-2 (Mfn-2) is a dynamin-like protein that involved in the rearrangement of outer mitochondrial membrane. Research using various experimental systems has shown Mfn-2 mediator fusion, an evolutionarily conserved process responsible for surveillance homeostasis. Here, we find cardiac myocyte mitochondria lacking are pleiomorphic and have propensity to become enlarged. Consistent with underlying mild dysfunction, Mfn-2-deficient mice display modest hypertrophy accompanied by slight...
The objective of this analysis was to evaluate and report on the economic impact implementing an integrated, quality, operational improvement program chronic obstructive pulmonary disease (COPD) care from acute through post-acute settings. This initiative established in a cohort 12 hospitals Alabama sought address COPD readmission improved workflows pertaining early diagnosis, efficient transitions, patient visibility across entire episode. Implementation influenced by lean principles,...
1,057 CMS Reimbursement to home medical equipment provider (HME) for NIV (AVAPS-AE (Trilogy 100)) device, supplies and supportive care (per month) 2019 Average.CPT code E0465, E0466 $11,400 Cost per Readmission (within 30-days of initial admission)
Neurodegenerative diseases are one of the leading public health challenges next 50 years. Pharmaceutical therapies have traditionally targeted later stages neurodegenerative diseases; however, this strategy - as recent failures clinical trials for Alzheimer’s drugs highlighted has been unsuccessful. Venture capital underperformed well during time, many new companies unable to maintain growth once they reach market and produced less than desirable returns. As a result, venture capitalists...
Mitochondrial ATP generation depends on the enormous potential across inner mitochondrial membrane (ΔΨmito ~ −180 mV), among many other factors. Oxidative phosphorylation requires large ΔΨmito and when mitochondria are depolarized, oxidative becomes uncoupled production falls. Here we investigate effect of hyperglycemia (30 mM versus physiological glucose 5 mM) under photonic stress in rat ventricular myocytes. Using tetra-methyl rhodamine methyl ester (TMRM) as a fluorescence monitor...
Abstract Background Migraine affects 1.1 billion people globally and is the second leading cause of disability worldwide. In clinical trials, treatment efficacy evaluated by comparing differential responses in placebo arms. Although response preventive migraine trials has been studied, there limited research examining temporal trends. This study evaluates trend over thirty years prevention investigates association potential confounders, such as patient, treatment, characteristics on using...